PHYOX2: a pivotal randomized study of nedosiran in primary hyperoxaluria type 1 or 2

Clinical characterization of primary hyperoxaluria type 3 in comparison with types 1 and 2

(2021) Prince Singh et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Hepatic Lactate Dehydrogenase A is an RNA Interference Target for the Treatment of All Known Types of Primary Hyperoxaluria

(2021) Gema Ariceta et al.   Kidney International Reports

A report from the European Hyperoxaluria Consortium (OxalEurope) Registry on a large cohort of patients with primary hyperoxaluria type 3

(2021) Cristina Martin-Higueras et al.   KIDNEY INTERNATIONAL

Lumasiran, an RNAi Therapeutic for Primary Hyperoxaluria Type 1

(2021) Sander F. Garrelfs et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety, pharmacodynamics, and exposure-response modeling results from a first in human phase 1 study of nedosiran in primary hyperoxaluria.

(2021) Bernd Hoppe et al.   KIDNEY INTERNATIONAL

Primary hyperoxaluria type 2 successfully treated with combined liver‐kidney transplantation after failure of isolated kidney transplantation

(2020) Arnaud Del Bello et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Endpoints for Clinical Trials in Primary Hyperoxaluria

(2020) Dawn S. Milliner et al.   Clinical Journal of the American Society of Nephrology

Reduction in urinary oxalate excretion in mouse models of Primary Hyperoxaluria by RNA interference inhibition of liver lactate dehydrogenase activity

(2019) Kyle D. Wood et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Patients with primary hyperoxaluria type 2 have significant morbidity and require careful follow-up

(2019) Sander F. Garrelfs et al.   KIDNEY INTERNATIONAL

Specific Inhibition of Hepatic Lactate Dehydrogenase Reduces Oxalate Production in Mouse Models of Primary Hyperoxaluria

(2018) Chengjung Lai et al.   MOLECULAR THERAPY

Metabolic profile and impact of diet in patients with primary hyperoxaluria

(2018) Roswitha Siener et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

An institutional experience of pre-emptive liver transplantation for pediatric primary hyperoxaluria type 1

(2016) Shirin Elizabeth Khorsandi et al.   PEDIATRIC TRANSPLANTATION

Predictors of Incident ESRD among Patients with Primary Hyperoxaluria Presenting Prior to Kidney Failure

(2015) F. Zhao et al.   Clinical Journal of the American Society of Nephrology

Phenotype-Genotype Correlations and Estimated Carrier Frequencies of Primary Hyperoxaluria

(2015) K. Hopp et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Data from a large European study indicate that the outcome of primary hyperoxaluria type 1 correlates with the AGXT mutation type

(2014) Giorgia Mandrile et al.   KIDNEY INTERNATIONAL

NALP3-mediated inflammation is a principal cause of progressive renal failure in oxalate nephropathy

(2013) Felix Knauf et al.   KIDNEY INTERNATIONAL

Primary Hyperoxaluria

(2013) Pierre Cochat et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hereditary causes of kidney stones and chronic kidney disease

(2013) Vidar O. Edvardsson et al.   PEDIATRIC NEPHROLOGY

Primary hyperoxalurias: Disorders of glyoxylate detoxification

(2012) Eduardo Salido et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Improved equations estimating GFR in children with chronic kidney disease using an immunonephelometric determination of cystatin C

(2012) George J. Schwartz et al.   KIDNEY INTERNATIONAL

An update on primary hyperoxaluria

(2012) Bernd Hoppe   Nature Reviews Nephrology

Primary hyperoxaluria Type 1: indications for screening and guidance for diagnosis and treatment

(2012) P. Cochat et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Estimating GFR Using the CKD Epidemiology Collaboration (CKD-EPI) Creatinine Equation: More Accurate GFR Estimates, Lower CKD Prevalence Estimates, and Better Risk Predictions

(2010) Andrew S. Levey et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Excellent renal function and reversal of nephrocalcinosis 8 years after isolated liver transplantation in an infant with primary hyperoxaluria type 1

(2010) Mónica Galanti et al.   PEDIATRIC NEPHROLOGY

Genotype–phenotype correlation in primary hyperoxaluria type 1: the p.Gly170Arg AGXT mutation is associated with a better outcome

(2009) Jérôme Harambat et al.   KIDNEY INTERNATIONAL