Hepatic Lactate Dehydrogenase A is an RNA Interference Target for the Treatment of All Known Types of Primary Hyperoxaluria

Endpoints for Clinical Trials in Primary Hyperoxaluria

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The current state and future directions of RNAi-based therapeutics

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Reduction in urinary oxalate excretion in mouse models of Primary Hyperoxaluria by RNA interference inhibition of liver lactate dehydrogenase activity

(2019) Kyle D. Wood et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Specific Inhibition of Hepatic Lactate Dehydrogenase Reduces Oxalate Production in Mouse Models of Primary Hyperoxaluria

(2018) Chengjung Lai et al.   MOLECULAR THERAPY

Hereditary lactate dehydrogenase M-subunit deficiency with late-developing pustular psoriasis-like lesions

(2016) Naoko Takeo et al.   JOURNAL OF DERMATOLOGY

The Regulation and Function of Lactate Dehydrogenase A: Therapeutic Potential in Brain Tumor

(2015) Cara J. Valvona et al.   BRAIN PATHOLOGY

Pustular psoriasis-like lesions associated with hereditary lactate dehydrogenase M subunit deficiency without interleukin-36 receptor antagonist mutation: long-term follow-up of two cases

(2015) T. Ito et al.   BRITISH JOURNAL OF DERMATOLOGY

Predictors of Incident ESRD among Patients with Primary Hyperoxaluria Presenting Prior to Kidney Failure

(2015) F. Zhao et al.   Clinical Journal of the American Society of Nephrology

Asialoglycoprotein receptor mediated hepatocyte targeting — Strategies and applications

(2015) Anisha A. D'Souza et al.   JOURNAL OF CONTROLLED RELEASE

Comprehensive review on lactate metabolism in human health

(2014) M. Adeva-Andany et al.   MITOCHONDRION

Primary hyperoxalurias: diagnosis and treatment

(2014) Efrat Ben-Shalom et al.   PEDIATRIC NEPHROLOGY

Small-molecule inhibitors of human LDH5

(2013) Carlotta Granchi et al.   Future Medicinal Chemistry

Targeting lactate metabolism for cancer therapeutics

(2013) Joanne R. Doherty et al.   JOURNAL OF CLINICAL INVESTIGATION

Primary Hyperoxaluria

(2013) Pierre Cochat et al.   NEW ENGLAND JOURNAL OF MEDICINE

An update on primary hyperoxaluria

(2012) Bernd Hoppe   Nature Reviews Nephrology