Primary tumor–derived systemic nANGPTL4 inhibits metastasis

ANGPTL4 influences the therapeutic response of neovascular age-related macular degeneration patients by promoting choroidal neovascularization

(2022) Yu Qin et al.   JCI Insight

Novel therapeutic targets for cancer metastasis

(2020) Konstantin Stoletov et al.   Expert Review of Anticancer Therapy

Primary tumor-induced immunity eradicates disseminated tumor cells in syngeneic mouse model

(2019) Raziye Piranlioglu et al.   Nature Communications

Defining the Hallmarks of Metastasis

(2019) Danny R. Welch et al.   CANCER RESEARCH

Angiopoietin-like 4 binds neuropilins and cooperates with VEGF to induce diabetic macular edema

(2019) Akrit Sodhi et al.   JOURNAL OF CLINICAL INVESTIGATION

Variations in common diseases, hospital admissions, and deaths in middle-aged adults in 21 countries from five continents (PURE): a prospective cohort study

(2019) Gilles R Dagenais et al.   LANCET

Are 90% of deaths from cancer caused by metastases?

(2019) Hanna Dillekås et al.   Cancer Medicine

Angiopoietin-like 4 promotes osteosarcoma cell proliferation and migration and stimulates osteoclastogenesis

(2018) T. Zhang et al.   BMC CANCER

Potential impact of invasive surgical procedures on primary tumor growth and metastasis

(2018) Maria Alieva et al.   CLINICAL & EXPERIMENTAL METASTASIS

Knockdown of angiopoietin-like 4 inhibits the development of human gastric cancer

(2018) Jin-Wu Chen et al.   ONCOLOGY REPORTS

The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy

(2018) Jordan A. Krall et al.   Science Translational Medicine

A review of the multifunctionality of angiopoietin-like 4 in eye disease

(2018) Xinyue Yang et al.   BIOSCIENCE REPORTS

Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4

(2018) Ryan Kolb et al.   ONCOGENE

OTP: An automatized system for managing and processing NGS data

(2017) Eva Reisinger et al.   JOURNAL OF BIOTECHNOLOGY

Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway

(2017) Laura La Paglia et al.   PPAR Research

ANGPTL4 promotes the progression of cutaneous melanoma to brain metastasis

(2017) Sivan Izraely et al.   Oncotarget

Primary Tumors Limit Metastasis Formation through Induction of IL15-Mediated Cross-Talk between Patrolling Monocytes and NK Cells

(2017) Hiroshi Kubo et al.   Cancer Immunology Research

Hypoxia-induced ANGPTL4 sustains tumour growth and anoikis resistance through different mechanisms in scirrhous gastric cancer cell lines

(2017) Koichi Baba et al.   Scientific Reports

Significance of Tissue Expression and Serum Levels of Angiopoietin-like Protein 4 in Breast Cancer Progression: Link to NF-κB /P65 Activity and Pro-Inflammatory Cytokines

(2016) Noha M Shafik et al.   Asian Pacific Journal of Cancer Prevention

ANGPTL4-αvβ3 interaction counteracts hypoxia-induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2

(2016) Elisa Gomez Perdiguero et al.   JOURNAL OF PATHOLOGY

Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease

(2016) Frederick E. Dewey et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epidermal growth factor-induced ANGPTL4 enhances anoikis resistance and tumour metastasis in head and neck squamous cell carcinoma

(2016) Y-H Liao et al.   ONCOGENE

Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma

(2016) Ke Hu et al.   Oncotarget

Novel endogenous angiogenesis inhibitors and their therapeutic potential

(2015) Nithya Rao et al.   ACTA PHARMACOLOGICA SINICA

Angiopoietin-like 4 Increases Pulmonary Tissue Leakiness and Damage during Influenza Pneumonia

(2015) Liang Li et al.   Cell Reports

Endothelial cell-derived non-canonical Wnt ligands control vascular pruning in angiogenesis

(2014) C. Korn et al.   DEVELOPMENT

Clinical relevance and therapeutic potential of angiopoietin-like protein 4 in hepatocellular carcinoma

(2014) Kevin Tak-Pan Ng et al.   Molecular Cancer

Regulation of lipoprotein lipase by Angptl4

(2014) Wieneke Dijk et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Syndecan-4 signaling at a glance

(2013) A. Elfenbein et al.   JOURNAL OF CELL SCIENCE

ANGPTL4 is a secreted tumor suppressor that inhibits angiogenesis

(2013) E Okochi-Takada et al.   ONCOGENE

Concomitant tumor resistance

(2012) Paula Chiarella et al.   CANCER LETTERS

Emerging Roles of Angiopoietin-like 4 in Human Cancer

(2012) Ming Jie Tan et al.   MOLECULAR CANCER RESEARCH

Systematic review and meta-analysis of Endostar (rh-endostatin) combined with chemotherapy versus chemotherapy alone for treating advanced non-small cell lung cancer

(2012) Rong Biaoxue et al.   World Journal of Surgical Oncology

ANGPTL4 modulates vascular junction integrity by integrin signaling and disruption of intercellular VE-cadherin and claudin-5 clusters

(2011) R.-L. Huang et al.   BLOOD

Angiopoietin-like 4 Protein Elevates the Prosurvival Intracellular O2−:H2O2 Ratio and Confers Anoikis Resistance to Tumors

(2011) Pengcheng Zhu et al.   CANCER CELL

Protection Against Myocardial Infarction and No-Reflow Through Preservation of Vascular Integrity by Angiopoietin-Like 4

(2011) Ariane Galaup et al.   CIRCULATION

Hypoxia-inducible factor 1 alpha-activated angiopoietin-like protein 4 contributes to tumor metastasis via vascular cell adhesion molecule-1/integrin β1 signaling in human hepatocellular carcinoma

(2011) Hong Li et al.   HEPATOLOGY

Proteolytic Processing of Angiopoietin-like Protein 4 by Proprotein Convertases Modulates Its Inhibitory Effects on Lipoprotein Lipase Activity

(2011) Xia Lei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Use of the mouse aortic ring assay to study angiogenesis

(2011) Marianne Baker et al.   Nature Protocols

Expression of angiopoietin-like 4 (ANGPTL4) in human colorectal cancer: ANGPTL4 promotes venous invasion and distant metastasis

(2011) Nakayama   ONCOLOGY REPORTS

A Mouse Model of the Cornea Pocket Assay for Angiogenesis Study

(2011) Zhongshu Tang et al.   Jove-Journal of Visualized Experiments

Angiopoietin-Like 4 Interacts with Integrins β1 and β5 to Modulate Keratinocyte Migration

(2010) Yan Yih Goh et al.   AMERICAN JOURNAL OF PATHOLOGY

Expression of angiopoietin-like 4 and tenascin C but not cathepsin C mRNA predicts prognosis of oral tongue squamous cell carcinoma

(2010) Zhuomin Wang et al.   BIOMARKERS

Clinicopathological significance of angiopoietin-like protein 4 expression in oesophageal squamous cell carcinoma

(2010) K. Shibata et al.   JOURNAL OF CLINICAL PATHOLOGY

Expression of angiopoietin-like 4 in human gastric cancer: ANGPTL4 promotes venous invasion

(2010) Nakayama   ONCOLOGY REPORTS

Viral G protein-coupled receptor up-regulates Angiopoietin-like 4 promoting angiogenesis and vascular permeability in Kaposi's sarcoma

(2010) T. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activating Peroxisome Proliferator-Activated Receptor   Mutant Promotes Tumor Growth In vivo by Enhancing Angiogenesis

(2009) L. Tian et al.   CANCER RESEARCH

Vascular morphogenesis: a Wnt for every vessel?

(2009) Claudio Areias Franco et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4

(2008) David Padua et al.   CELL

Molecular Basis of Metastasis

(2008) Anne C. Chiang et al.   NEW ENGLAND JOURNAL OF MEDICINE