Novel endogenous angiogenesis inhibitors and their therapeutic potential

The endogenous zinc finger transcription factor, ZNF24, modulates the angiogenic potential of human microvascular endothelial cells

(2015) Di Jia et al.   FASEB JOURNAL

TAp73 promotes cell survival upon genotoxic stress by inhibiting p53 activity

(2015) Dongshi Chen et al.   Oncotarget

Isthmin targets cell-surface GRP78 and triggers apoptosis via induction of mitochondrial dysfunction

(2014) M Chen et al.   CELL DEATH AND DIFFERENTIATION

TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation

(2014) Ivano Amelio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rho GAPs and GEFs

(2014) Jaap D van Buul et al.   Cell Adhesion & Migration

ING4 regulates JWA in angiogenesis and their prognostic value in melanoma patients

(2013) J Lu et al.   BRITISH JOURNAL OF CANCER

JWA inhibits melanoma angiogenesis by suppressing ILK signaling and is an independent prognostic biomarker for melanoma

(2013) Jing Lu et al.   CARCINOGENESIS

JWA suppresses tumor angiogenesis via Sp1-activated matrix metalloproteinase-2 and its prognostic significance in human gastric cancer

(2013) Yansu Chen et al.   CARCINOGENESIS

Venous malformation-causative TIE2 mutations mediate an AKT-dependent decrease in PDGFB

(2013) Melanie Uebelhoer et al.   HUMAN MOLECULAR GENETICS

Zinc finger protein 191 deficiency attenuates vascular smooth muscle cell proliferation, migration, and intimal hyperplasia after endovascular arterial injury

(2013) Lei Lv et al.   JOURNAL OF VASCULAR SURGERY

TAp73 enhances the pentose phosphate pathway and supports cell proliferation

(2013) Wenjing Du et al.   NATURE CELL BIOLOGY

VEGF and Notch in Tip and Stalk Cell Selection

(2013) R. Blanco et al.   Cold Spring Harbor Perspectives in Medicine

Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited

(2012) Karl H. Plate et al.   ACTA NEUROPATHOLOGICA

SOCS3 is an endogenous inhibitor of pathologic angiogenesis

(2012) A. Stahl et al.   BLOOD

Transcriptional repression of VEGF by ZNF24: mechanistic studies and vascular consequences in vivo

(2012) D. Jia et al.   BLOOD

PRAF3 induces apoptosis and inhibits migration and invasion in human esophageal squamous cell carcinoma

(2012) Guo-Zhen Shi et al.   BMC CANCER

TNFα and SOCS3 regulate IRS-1 to increase retinal endothelial cell apoptosis

(2012) Youde Jiang et al.   CELLULAR SIGNALLING

GPR56 in cancer progression: current status and future perspective

(2012) Liquan Yang et al.   Future Oncology

CHIP functions as a novel suppressor of tumour angiogenesis with prognostic significance in human gastric cancer

(2012) Shouyu Wang et al.   GUT

Isthmin inhibits glioma growth through antiangiogenesis in vivo

(2012) Bangqing Yuan et al.   JOURNAL OF NEURO-ONCOLOGY

p53 mutations in cancer

(2012) Patricia A. J. Muller et al.   NATURE CELL BIOLOGY

Systematic review and meta-analysis of Endostar (rh-endostatin) combined with chemotherapy versus chemotherapy alone for treating advanced non-small cell lung cancer

(2012) Rong Biaoxue et al.   World Journal of Surgical Oncology

Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting

(2011) Min Ni et al.   BIOCHEMICAL JOURNAL

GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

(2011) L. Yang et al.   CANCER RESEARCH

Carboxyl terminus of Hsp70-interacting protein (CHIP) contributes to human glioma oncogenesis

(2011) Tao Xu et al.   CANCER SCIENCE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

FKBPL and Peptide Derivatives: Novel Biological Agents That Inhibit Angiogenesis by a CD44-Dependent Mechanism

(2011) A. Valentine et al.   CLINICAL CANCER RESEARCH

Zinc finger transcription factor 191, directly binding to β-catenin promoter, promotes cell proliferation of hepatocellular carcinoma

(2011) Guoyuan Liu et al.   HEPATOLOGY

The C-terminus of Hsp70-Interacting Protein Promotes Met Receptor Degradation

(2011) Kang Won Jang et al.   Journal of Thoracic Oncology

ARHGAP18, a GTPase-activating protein for RhoA, controls cell shape, spreading, and motility

(2011) Masao Maeda et al.   MOLECULAR BIOLOGY OF THE CELL

MULTIMERIN2 impairs tumor angiogenesis and growth by interfering with VEGF-A/VEGFR2 pathway

(2011) E Lorenzon et al.   ONCOGENE

Breaking the ‘harmony’ of TNF-α signaling for cancer treatment

(2011) S P Sasi et al.   ONCOGENE

5-Lipoxygenase Metabolite 4-HDHA Is a Mediator of the Antiangiogenic Effect of  -3 Polyunsaturated Fatty Acids

(2011) P. Sapieha et al.   Science Translational Medicine

Isthmin exerts pro-survival and death-promoting effect on endothelial cells through alphavbeta5 integrin depending on its physical state

(2011) Y Zhang et al.   Cell Death & Disease

Characterization of the target DNA sequence for the DNA-binding domain of zinc finger protein 191

(2010) H. Wang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

New member of the guanosine triphosphatase activating protein family in the human epididymis

(2010) X. Li et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

The transcriptional repression of platelet-derived growth factor receptor-β by the zinc finger transcription factor ZNF24

(2010) Jianzhong Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Stress-induced premature senescence mediated by a novel gene, SENEX, results in an anti-inflammatory phenotype in endothelial cells

(2010) P. R. Coleman et al.   BLOOD

Targeting plasma membrane GRP78 for cancer growth inhibition

(2010) Steve Schwarze et al.   CANCER BIOLOGY & THERAPY

FKBPL Regulates Estrogen Receptor Signaling and Determines Response to Endocrine Therapy

(2010) H. D. McKeen et al.   CANCER RESEARCH

Hypoxia and Hypoxia-Inducible Factors: Master Regulators of Metastasis

(2010) X. Lu et al.   CLINICAL CANCER RESEARCH

ZFP191 is required by oligodendrocytes for CNS myelination

(2010) S. Y. B. Howng et al.   GENES & DEVELOPMENT

Loss of SOCS3 expression is associated with an increased risk of recurrent disease in breast carcinoma

(2010) Mingzhen Ying et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

(2010) S. A. Forbes et al.   NUCLEIC ACIDS RESEARCH

The Chaperone-Dependent Ubiquitin Ligase CHIP Targets HIF-1α for Degradation in the Presence of Methylglyoxal

(2010) Carla Figueira Bento et al.   PLoS One

Alterations in the steroid hormone receptor co-chaperone FKBPL are associated with male infertility: a case-control study

(2010) Olaf Sunnotel et al.   Reproductive Biology and Endocrinology

CHIP functions an E3 ubiquitin ligase of Runx1

(2009) Yu Shang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Isthmin is a novel secreted angiogenesis inhibitor that inhibits tumour growth in mice

(2009) Wei Xiang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Genetic Alterations and Oncogenic Pathways Associated with Breast Cancer Subtypes

(2009) X. Hu et al.   MOLECULAR CANCER RESEARCH

The ubiquitin ligase CHIP acts as an upstream regulator of oncogenic pathways

(2009) Masashi Kajiro et al.   NATURE CELL BIOLOGY

JWA regulates melanoma metastasis by integrin αVβ3 signaling

(2009) J Bai et al.   ONCOGENE

The ADP and ATP transport in mitochondria and its carrier

(2008) Martin Klingenberg   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

A Novel FK506-Like Binding Protein Interacts with the Glucocorticoid Receptor and Regulates Steroid Receptor Signaling

(2008) Hayley D. McKeen et al.   ENDOCRINOLOGY

Differential roles of PDGFR-α and PDGFR-β in angiogenesis and vessel stability

(2008) Junhang Zhang et al.   FASEB JOURNAL

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

(2008) R. Tomasini et al.   GENES & DEVELOPMENT

Tumor Cavitation: Impact on Objective Response Evaluation in Trials of Angiogenesis Inhibitors in Non–Small-Cell Lung Cancer

(2008) Simon J. Crabb et al.   JOURNAL OF CLINICAL ONCOLOGY

Chaperone-dependent stabilization and degradation of p53 mutants

(2008) P Muller et al.   ONCOGENE

Hyaluronan-mediated CD44 activation of RhoGTPase signaling and cytoskeleton function promotes tumor progression

(2008) Lilly Y.W. Bourguignon   SEMINARS IN CANCER BIOLOGY

Expression of the transcription factor Zfp191 during embryonic development in the mouse

(2007) Olfa Khalfallah et al.   GENE EXPRESSION PATTERNS