Angiopoietin-like 4 promotes osteosarcoma cell proliferation and migration and stimulates osteoclastogenesis

HIF-2α affects proliferation and apoptosis of MG-63 osteosarcoma cells through MAPK signaling

(2017) Yuqiang Wang et al.   Molecular Medicine Reports

MicroRNA-33b Inhibits the Proliferation and Migration of Osteosarcoma Cells via Targeting Hypoxia-Inducible Factor-1α

(2017) Yong Zhou et al.   ONCOLOGY RESEARCH

Hypoxia-induced ANGPTL4 sustains tumour growth and anoikis resistance through different mechanisms in scirrhous gastric cancer cell lines

(2017) Koichi Baba et al.   Scientific Reports

Overcoming cisplatin resistance in osteosarcoma through the miR-199a-modulated inhibition of HIF-1α

(2017) Ajimu Keremu et al.   BIOSCIENCE REPORTS

Combined over-expression of the hypoxia-inducible factor 2α gene and its long non-coding RNA predicts unfavorable prognosis of patients with osteosarcoma

(2016) Wei Li et al.   PATHOLOGY RESEARCH AND PRACTICE

Prognosis value of Hypoxia-inducible factor-1α expression in patients with bone and soft tissue sarcoma: a meta-analysis

(2016) Yongjiang Li et al.   SpringerPlus

Angiopoietin-like 4 enhances metastasis and inhibits apoptosis via inducing bone morphogenetic protein 7 in colorectal cancer cells

(2015) Xuquan Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DEC2 expression is positively correlated with HIF-1 activation and the invasiveness of human osteosarcomas

(2015) Tu Hu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

X609, a novel manassantin A derivative, exhibits antitumor activity in MG-63 human osteosarcoma cells in vitro and in vivo

(2015) JI LI et al.   Molecular Medicine Reports

Regulation and clinical significance of the hypoxia-induced expression of ANGPTL4 in gastric cancer

(2015) HIROSHI KUBO et al.   Oncology Letters

Intermittent Induction of HIF-1α Produces Lasting Effects on Malignant Progression Independent of Its Continued Expression

(2015) Hyunsung Choi et al.   PLoS One

Bisphosphonates Inhibit Osteosarcoma-Mediated Osteolysis Via Attenuation of Tumor Expression of MCP-1 and RANKL

(2014) Tetsuro Ohba et al.   JOURNAL OF BONE AND MINERAL RESEARCH

ANGPTL4 regulates the metastatic potential of oral squamous cell carcinoma

(2014) Junichi Tanaka et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Angiopoietin-Like 4 Is Over-Expressed in Rheumatoid Arthritis Patients: Association with Pathological Bone Resorption

(2014) Catherine Swales et al.   PLoS One

Osteogenic tumors of bone

(2014) Jeffery T. Green et al.   SEMINARS IN DIAGNOSTIC PATHOLOGY

Regulation of lipoprotein lipase by Angptl4

(2014) Wieneke Dijk et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Skeletal Actions of Fasting-Induced Adipose Factor (FIAF)

(2013) Jian-ming Lin et al.   ENDOCRINOLOGY

Emerging Roles of Angiopoietin-like 4 in Human Cancer

(2012) Ming Jie Tan et al.   MOLECULAR CANCER RESEARCH

Predicting chemosensitivity in osteosarcoma prior to chemotherapy: An investigational study of biomarkers with immunohistochemistry

(2012) YONG CHEN et al.   Oncology Letters

Angiopoietin-like 4 (Angptl4)

(2012) Suneil K. Koliwad et al.   Adipocyte

Angiopoietin-like 4: a decade of research

(2011) Pengcheng Zhu et al.   BIOSCIENCE REPORTS

ANGPTL4 modulates vascular junction integrity by integrin signaling and disruption of intercellular VE-cadherin and claudin-5 clusters

(2011) R.-L. Huang et al.   BLOOD

Angiopoietin-like 4 Protein Elevates the Prosurvival Intracellular O2−:H2O2 Ratio and Confers Anoikis Resistance to Tumors

(2011) Pengcheng Zhu et al.   CANCER CELL

ANGPTL4 Induction by Prostaglandin E2 under Hypoxic Conditions Promotes Colorectal Cancer Progression

(2011) S.-H. Kim et al.   CANCER RESEARCH

Hypoxia-inducible factor 1 alpha-activated angiopoietin-like protein 4 contributes to tumor metastasis via vascular cell adhesion molecule-1/integrin β1 signaling in human hepatocellular carcinoma

(2011) Hong Li et al.   HEPATOLOGY

Proteolytic Processing of Angiopoietin-like Protein 4 by Proprotein Convertases Modulates Its Inhibitory Effects on Lipoprotein Lipase Activity

(2011) Xia Lei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reciprocal osteoblastic and osteoclastic modulation in co-cultured MG63 osteosarcoma cells and human osteoclast precursors

(2011) João Costa-Rodrigues et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs

(2011) H Zhang et al.   ONCOGENE

Expression of angiopoietin-like 4 (ANGPTL4) in human colorectal cancer: ANGPTL4 promotes venous invasion and distant metastasis

(2011) Nakayama   ONCOLOGY REPORTS

Downregulation of S100A4 expression by RNA interference suppresses cell growth and invasion in human colorectal cancer cells

(2011) LIYONG HUANG et al.   ONCOLOGY REPORTS

Expression of angiopoietin-like 4 and tenascin C but not cathepsin C mRNA predicts prognosis of oral tongue squamous cell carcinoma

(2010) Zhuomin Wang et al.   BIOMARKERS

Hypoxia and hypoglycaemia in Ewing's sarcoma and osteosarcoma: regulation and phenotypic effects of Hypoxia-Inducible Factor

(2010) Helen J Knowles et al.   BMC CANCER

Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4

(2010) Helen J. Knowles et al.   FASEB JOURNAL

Clinicopathological significance of angiopoietin-like protein 4 expression in oesophageal squamous cell carcinoma

(2010) K. Shibata et al.   JOURNAL OF CLINICAL PATHOLOGY

Expression of angiopoietin-like 4 in human gastric cancer: ANGPTL4 promotes venous invasion

(2010) Nakayama   ONCOLOGY REPORTS

Different atrophy-hypertrophy transcription pathways in muscles affected by severe and mild spinal muscular atrophy

(2009) Caterina Millino et al.   BMC Medicine

Activating Peroxisome Proliferator-Activated Receptor   Mutant Promotes Tumor Growth In vivo by Enhancing Angiogenesis

(2009) L. Tian et al.   CANCER RESEARCH

Molecular characterization of commonly used cell lines for bone tumor research: A trans-European EuroBoNet effort

(2009) Laura Ottaviano et al.   GENES CHROMOSOMES & CANCER

Proteasome inhibition with bortezomib suppresses growth and induces apoptosis in osteosarcoma

(2009) Yuriy Shapovalov et al.   INTERNATIONAL JOURNAL OF CANCER

Angiopoietin-like 4 (ANGPTL4, Fasting-induced Adipose Factor) Is a Direct Glucocorticoid Receptor Target and Participates in Glucocorticoid-regulated Triglyceride Metabolism

(2009) Suneil K. Koliwad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acquisition of anoikis resistance reveals a synoikis-like survival style in BEL7402 hepatoma cells

(2008) Zhiyong Zhang et al.   CANCER LETTERS

TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4

(2008) David Padua et al.   CELL

Hypoxia Markers in Human Osteosarcoma: An Exploratory Study

(2008) Hiroo Mizobuchi et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Hypoxia-inducible factor is expressed in giant cell tumour of bone and mediates paracrine effects of hypoxia on monocyte–osteoclast differentiation via induction of VEGF

(2008) HJ Knowles et al.   JOURNAL OF PATHOLOGY

Novel therapeutic strategy for osteosarcoma targeting osteoclast differentiation, bone-resorbing activity, and apoptosis pathway

(2008) T. Akiyama et al.   MOLECULAR CANCER THERAPEUTICS