Prediction the clinical EPR effect of nanoparticles in patient-derived xenograft models

Microfluidic Reconstitution of Tumor Microenvironment for Nanomedical Applications

(2021) Hyun Jeong Oh et al.   Advanced Healthcare Materials

Patient-derived microvesicles/AIE luminogen hybrid system for personalized sonodynamic cancer therapy in patient-derived xenograft models

(2021) Yanhong Duo et al.   BIOMATERIALS

Co-clinical FDG-PET radiomic signature in predicting response to neoadjuvant chemotherapy in triple-negative breast cancer

(2021) Sudipta Roy et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

A Tumor‐Targeting Metal‐Organic Nanoparticle Constructed by Dynamic Combinatorial Chemistry toward Accurately Redressing Carcinogenic Wnt Cascade

(2021) Tianya Liu et al.   Small

Smart transformable nanoparticles for enhanced tumor theranostics

(2021) Jinjin Chen et al.   Applied Physics Reviews

Tumor‐Targeting Glycol Chitosan Nanoparticles for Cancer Heterogeneity

(2020) Ju Hee Ryu et al.   ADVANCED MATERIALS

Diversity in the Extracellular Vesicle-Derived Microbiome of Tissues According to Tumor Progression in Pancreatic Cancer

(2020) Jin-Yong Jeong et al.   Cancers

Breaking the Intracellular Redox Balance with Diselenium Nanoparticles for Maximizing Chemotherapy Efficacy on Patient-Derived Xenograft Models

(2020) Dengshuai Wei et al.   ACS Nano

Coated cationic lipid-nanoparticles entrapping miR-660 inhibit tumor growth in patient-derived xenografts lung cancer models

(2019) Massimo Moro et al.   JOURNAL OF CONTROLLED RELEASE

HALO-109–301: a Phase III trial of PEGPH20 (with gemcitabine and nab-paclitaxel) in hyaluronic acid-high stage IV pancreatic cancer

(2018) Gary J Doherty et al.   Future Oncology

Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models

(2018) Michael L Schulte et al.   NATURE MEDICINE

Effects of tumor microenvironments on targeted delivery of glycol chitosan nanoparticles

(2017) Ji Young Yhee et al.   JOURNAL OF CONTROLLED RELEASE

Tumor engraftment in patient-derived xenografts of pancreatic ductal adenocarcinoma is associated with adverse clinicopathological features and poor survival

(2017) Ilaria Pergolini et al.   PLoS One

Role of hyaluronan in pancreatic cancer biology and therapy: Once again in the spotlight

(2016) Norihiro Sato et al.   CANCER SCIENCE

To exploit the tumor microenvironment: Since the EPR effect fails in the clinic, what is the future of nanomedicine?

(2016) F. Danhier   JOURNAL OF CONTROLLED RELEASE

Patient-derived xenografts: a relevant preclinical model for drug development

(2016) Luca Pompili et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Improving nanoparticle diffusion through tumor collagen matrix by photo-thermal gold nanorods

(2016) Vahid Raeesi et al.   Nanoscale

Targeting hyaluronan for the treatment of pancreatic ductal adenocarcinoma

(2016) Norihiro Sato et al.   Acta Pharmaceutica Sinica B

Impaired Synthesis of Stromal Components in Response to Minnelide Improves Vascular Function, Drug Delivery, and Survival in Pancreatic Cancer

(2015) S. Banerjee et al.   CLINICAL CANCER RESEARCH

Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer

(2015) C. J. Whatcott et al.   CLINICAL CANCER RESEARCH

Establishment of patient-derived xenograft models and cell lines for malignancies of the upper gastrointestinal tract

(2015) Helene Damhofer et al.   Journal of Translational Medicine

A versatile gold cross-linked nanoparticle based on triblock copolymer as the carrier of doxorubicin

(2015) Sangmin Jeon et al.   RSC Advances

Capillary-Wall Collagen as a Biophysical Marker of Nanotherapeutic Permeability into the Tumor Microenvironment

(2014) K. Yokoi et al.   CANCER RESEARCH

Challenges associated with penetration of nanoparticles across cell and tissue barriers: A review of current status and future prospects

(2014) Sutapa Barua et al.   Nano Today

Patient-Derived Xenograft Models: An Emerging Platform for Translational Cancer Research

(2014) M. Hidalgo et al.   Cancer Discovery

Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology

(2013) Nicolas Bertrand et al.   ADVANCED DRUG DELIVERY REVIEWS

Challenges and Key Considerations of the Enhanced Permeability and Retention Effect for Nanomedicine Drug Delivery in Oncology

(2013) U. Prabhakar et al.   CANCER RESEARCH

Heterogeneity in nanoparticles influences biodistribution and targeting

(2013) Isaac M Adjei et al.   Nanomedicine

Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma

(2012) Paolo P. Provenzano et al.   CANCER CELL

Effect of the stability and deformability of self-assembled glycol chitosan nanoparticles on tumor-targeting efficiency

(2012) Jin Hee Na et al.   JOURNAL OF CONTROLLED RELEASE

In Vivo Targeted Delivery of Nanoparticles for Theranosis

(2011) Heebeom Koo et al.   ACCOUNTS OF CHEMICAL RESEARCH

Real-time and non-invasive optical imaging of tumor-targeting glycol chitosan nanoparticles in various tumor models

(2011) Jin Hee Na et al.   BIOMATERIALS

Targeted drug delivery to tumors: Myths, reality and possibility

(2011) You Han Bae et al.   JOURNAL OF CONTROLLED RELEASE

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

(2011) H. Cabral et al.   Nature Nanotechnology

Tumor-homing multifunctional nanoparticles for cancer theragnosis: Simultaneous diagnosis, drug delivery, and therapeutic monitoring

(2010) Kwangmeyung Kim et al.   JOURNAL OF CONTROLLED RELEASE

Of Mice and Humans: Are They the Same?--Implications in Cancer Translational Research

(2010) M. de Jong et al.   JOURNAL OF NUCLEAR MEDICINE

Combinatorial Drug Conjugation Enables Nanoparticle Dual-Drug Delivery

(2010) Santosh Aryal et al.   Small

Type IV collagen is a tumour stroma-derived biomarker for pancreas cancer

(2009) D Öhlund et al.   BRITISH JOURNAL OF CANCER

Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticles

(2009) Hae Yun Nam et al.   JOURNAL OF CONTROLLED RELEASE

Antitumor efficacy of cisplatin-loaded glycol chitosan nanoparticles in tumor-bearing mice

(2008) Jong-Ho Kim et al.   JOURNAL OF CONTROLLED RELEASE