Establishment of patient-derived xenograft models and cell lines for malignancies of the upper gastrointestinal tract

The conflicting roles of tumor stroma in pancreatic cancer and their contribution to the failure of clinical trials: a systematic review and critical appraisal

(2015) Maarten F. Bijlsma et al.   CANCER AND METASTASIS REVIEWS

Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States

(2014) L. Rahib et al.   CANCER RESEARCH

Blocking Hedgehog release from pancreatic cancer cells increases paracrine signaling potency

(2014) H. Damhofer et al.   JOURNAL OF CELL SCIENCE

Patient-Derived Xenograft Models: An Emerging Platform for Translational Cancer Research

(2014) M. Hidalgo et al.   Cancer Discovery

Hedgehog Signaling Pathway and Cancer Therapeutics: Progress to Date

(2013) Joshua M. Ruch et al.   DRUGS

Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine

(2013) Daniel D. Von Hoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Crosstalk of mTOR/S6K1 and Hedgehog Pathways

(2012) Yan Wang et al.   CANCER CELL

Hedgehog signalling stimulates precursor cell accumulation and impairs epithelial maturation in the murine oesophagus

(2012) Willemijn A van Dop et al.   GUT

Characterization of human pancreatic orthotopic tumor xenografts suitable for drug screening

(2011) Sandra Pérez-Torras et al.   CELLULAR ONCOLOGY

Combinatorial Chemoprevention Reveals a Novel Smoothened-Independent Role of GLI1 in Esophageal Carcinogenesis

(2010) S. Rizvi et al.   CANCER RESEARCH

Aberrant Epithelial–Mesenchymal Hedgehog Signaling Characterizes Barrett's Metaplasia

(2010) David H. Wang et al.   GASTROENTEROLOGY

Verification and Unmasking of Widely Used Human Esophageal Adenocarcinoma Cell Lines

(2010) Jurjen J. Boonstra et al.   JNCI-Journal of the National Cancer Institute

Sonic hedgehog paracrine signaling regulates metastasis and lymphangiogenesis in pancreatic cancer

(2009) J M Bailey et al.   ONCOGENE

Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis

(2009) H. Tian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

A paracrine requirement for hedgehog signalling in cancer

(2008) Robert L. Yauch et al.   NATURE