Exploration of the underlying mechanisms of isoniazid/rifampicin‐induced liver injury in mice using an integrated proteomics and metabolomics approach

Gallic acid attenuates isoniazid and rifampicin-induced liver injury by improving hepatic redox homeostasis through influence on Nrf2 and NF-κB signalling cascades in Wistar Rats

(2021) Sukumaran Sanjay et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Antituberculosis Drugs (Rifampicin and Isoniazid) Induce Liver Injury by Regulating NLRP3 Inflammasomes

(2021) Qiang Su et al.   MEDIATORS OF INFLAMMATION

Incidence and risk factors of anti‐tuberculosis drug induced liver injury (DILI): Large cohort study involving 4652 Chinese adult tuberculosis patients

(2021) Fanrong Jiang et al.   LIVER INTERNATIONAL

Integrated metabolomics and proteomics analysis reveals energy metabolism disorders in the livers of sleep-deprived mice

(2021) Shuang Hu et al.   Journal of Proteomics

Shaping the mitochondrial inner membrane in health and disease

(2020) L. Colina‐Tenorio et al.   JOURNAL OF INTERNAL MEDICINE

PPAR-Mediated Toxicology and Applied Pharmacology

(2020) Yue Xi et al.   Cells

PPARs as Metabolic Regulators in the Liver: Lessons from Liver-Specific PPAR-Null Mice

(2020) Yaping Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bioinformatics Methods for Mass Spectrometry-Based Proteomics Data Analysis

(2020) Chen Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lipidomics: an omics discipline with a key role in nutrition

(2020) M.D. Luque de Castro et al.   TALANTA

Metabolomics describes previously unknown toxicity mechanisms of isoniazid and rifampicin

(2020) Monique Combrink et al.   TOXICOLOGY LETTERS

Tryptophan Metabolism, Inflammation, and Oxidative Stress in Patients with Neurovascular Disease

(2020) Martin Hajsl et al.   Metabolites

Ferroptosis in Liver Diseases: An Overview

(2020) Martina Maria Capelletti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Integrative proteomics-metabolomics strategy reveals the mechanism of hepatotoxicity induced by Fructus Psoraleae

(2020) Jingyi Duan et al.   Journal of Proteomics

Toxicoproteomic Profiling of hPXR Transgenic Mice Treated with Rifampicin and Isoniazid

(2020) Christopher Trent Brewer et al.   Cells

Multi-omics integration in biomedical research – A metabolomics-centric review

(2020) Maria A. Wörheide et al.   ANALYTICA CHIMICA ACTA

UPLC-MS-based urine nontargeted metabolic profiling identifies dysregulation of pantothenate and CoA biosynthesis pathway in diabetic kidney disease

(2020) Tao Ma et al.   LIFE SCIENCES

Pyridoxal isonicotinoyl hydrazone inhibition of FXR is involved in the pathogenesis of isoniazid-induced liver injury

(2020) Guoqiang Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Recurrent Topics in Mass Spectrometry-Based Metabolomics and Lipidomics—Standardization, Coverage, and Throughput

(2020) Evelyn Rampler et al.   ANALYTICAL CHEMISTRY

Lipid peroxidation aggravates anti-tuberculosis drug-induced liver injury: Evidence of ferroptosis induction

(2020) Yunzhi Pan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Metabolomics meets lipidomics: Assessing the small molecule component of metabolism

(2020) Hector Gallart‐Ayala et al.   BIOESSAYS

Integration of proteomics, lipidomics, and metabolomics reveals novel metabolic mechanisms underlying N, N-dimethylformamide induced hepatotoxicity

(2020) Lin Xu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Identification of bioactive metabolites using activity metabolomics

(2019) Markus M. Rinschen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Disorders of riboflavin metabolism

(2019) Shanti Balasubramaniam et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Integrated Proteomics, Biological Functional Assessments, and Metabolomics Reveal Toosendanin-Induced Hepatic Energy Metabolic Disorders

(2019) Xiaojing Yan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Energy metabolism modulation by biguanides in comparison with rotenone in rat liver and heart

(2019) Sabrina Heinz et al.   ARCHIVES OF TOXICOLOGY

Immunoregulatory Interplay Between Arginine and Tryptophan Metabolism in Health and Disease

(2019) Giada Mondanelli et al.   Frontiers in Immunology

FSP1 is a glutathione-independent ferroptosis suppressor

(2019) Sebastian Doll et al.   NATURE

Tryptophan Metabolism in Inflammaging: From Biomarker to Therapeutic Target

(2019) Freek J. H. Sorgdrager et al.   Frontiers in Immunology

Integrative omics for health and disease

(2018) Konrad J. Karczewski et al.   NATURE REVIEWS GENETICS

Mechanism Investigation of Rifampicin-Induced Liver Injury Using Comparative Toxicoproteomics in Mice

(2017) Ju-Hyun Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

Ferroptosis is an autophagic cell death process

(2016) Minghui Gao et al.   CELL RESEARCH

Taurine ameliorates cholesterol metabolism by stimulating bile acid production in high-cholesterol-fed rats

(2016) Shigeru Murakami et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Optimizing treatment outcome of first-line anti-tuberculosis drugs: the role of therapeutic drug monitoring

(2016) Roger K. Verbeeck et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

The tryptophan metabolism enzyme L-kynureninase is a novel inflammatory factor in psoriasis and other inflammatory diseases

(2016) Jamie L. Harden et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Hesperidin Alleviates Oxidative Stress and Upregulates the Multidrug Resistance Protein 2 in Isoniazid and Rifampicin-Induced Liver Injury in Rats

(2016) Guoqiang Zhang et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Metabolomics: beyond biomarkers and towards mechanisms

(2016) Caroline H. Johnson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Isoniazid metabolism and hepatotoxicity

(2016) Pengcheng Wang et al.   Acta Pharmaceutica Sinica B

Plasma lipidomics reveal profound perturbation of glycerophospholipids, fatty acids, and sphingolipids in diet-induced hyperlipidemia

(2015) Hua Miao et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The role of skeletal muscle in liver glutathione metabolism during acetaminophen overdose

(2015) L.M. Bilinsky et al.   JOURNAL OF THEORETICAL BIOLOGY

The inhibition of hepatic bile acids transporters Ntcp and Bsep is involved in the pathogenesis of isoniazid/rifampicin-induced hepatotoxicity

(2015) Yao Xue Guo et al.   TOXICOLOGY MECHANISMS AND METHODS

The inhibition of hepatic bile acids transporters Ntcp and Bsep is involved in the pathogenesis of isoniazid/rifampicin-induced hepatotoxicity

(2015) Yao Xue Guo et al.   TOXICOLOGY MECHANISMS AND METHODS

The human flavoproteome

(2013) Wolf-Dieter Lienhart et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Involvement of a di-leucine motif in targeting of ABCC1 to the basolateral plasma membrane of polarized epithelial cells

(2013) Yoshikazu Emi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A large-scale method to measure absolute protein phosphorylation stoichiometries

(2011) Ronghu Wu et al.   NATURE METHODS

Bile acids as regulatory molecules

(2009) Phillip B. Hylemon et al.   JOURNAL OF LIPID RESEARCH

Mitochondrial energetic metabolism: A simplified model of TCA cycle with ATP production

(2008) Christine Nazaret et al.   JOURNAL OF THEORETICAL BIOLOGY