Exploring the Antitumor Potential of Copper Complexes Based on Ester Derivatives of Bis(pyrazol-1-yl)acetate Ligands

Cu(I) and Cu(II) Complexes Based on Lonidamine-Conjugated Ligands Designed to Promote Synergistic Antitumor Effects

(2022) Fabio Del Bello et al.   INORGANIC CHEMISTRY

PDI-Regulated Disulfide Bond Formation in Protein Folding and Biomolecular Assembly

(2021) Jiahui Fu et al.   MOLECULES

High copper complex stability and slow reduction kinetics as key parameters for improved activity, paraptosis induction and impact on drug-resistant cells of anticancer thiosemicarbazones

(2020) Sonja Hager et al.   ANTIOXIDANTS & REDOX SIGNALING

Synthesis and Cytotoxic Activity Evaluation of New Cu(I) Complexes of Bis(pyrazol-1-yl) Acetate Ligands Functionalized with an NMDA Receptor Antagonist

(2020) Maura Pellei et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Copper Coordination Compounds as Biologically Active Agents

(2020) Olga Krasnovskaya et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Modeling neoplastic disease with spheroids and organoids

(2020) Michele Zanoni et al.   Journal of Hematology & Oncology

Anticancer potency of copper(II) complexes of thiosemicarbazones

(2020) Narendra Kumar Singh et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Copper Complexes as Anticancer Agents Targeting Topoisomerases I and II

(2020) Caroline Molinaro et al.   Cancers

The Multifaceted Roles of Copper in Cancer: A Trace Metal Element with Dysregulated Metabolism, but Also a Target or a Bullet for Therapy

(2020) Pierre Lelièvre et al.   Cancers

X-ray structures of the high-affinity copper transporter Ctr1

(2019) Feifei Ren et al.   Nature Communications

Interactions of copper complexes with nucleic acids

(2018) Andrea Erxleben   COORDINATION CHEMISTRY REVIEWS

Novel antitumor copper(ii) complexes designed to act through synergistic mechanisms of action, due to the presence of an NMDA receptor ligand and copper in the same chemical entity

(2018) Maria Beatrice Morelli et al.   NEW JOURNAL OF CHEMISTRY

The thiosemicarbazone Me2NNMe2 induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition

(2018) Sonja Hager et al.   Cell Death & Disease

Anti-proliferative effects of copper(II) complexes with hydroxyquinoline-thiosemicarbazone ligands

(2017) Dominga Rogolino et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Endoplasmic Reticulum Stress, Unfolded Protein Response, and Cancer Cell Fate

(2017) Marco Corazzari et al.   Frontiers in Oncology

Therapeutic potential of the phosphino Cu(I) complex (HydroCuP) in the treatment of solid tumors

(2017) Valentina Gandin et al.   Scientific Reports

Metal-based drugs that break the rules

(2016) Claire S. Allardyce et al.   DALTON TRANSACTIONS

Current and future potential of metallo drugs: Revisiting DNA-binding of metal containing molecules and their diverse mechanism of action

(2016) Mehvash Zaki et al.   INORGANICA CHIMICA ACTA

Antineoplastic copper coordinated complexes (Casiopeinas) uncouple oxidative phosphorylation and induce mitochondrial permeability transition in cardiac mitochondria and cardiomyocytes

(2016) Christian Silva-Platas et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Noble metals in medicine: Latest advances

(2015) Serenella Medici et al.   COORDINATION CHEMISTRY REVIEWS

Homoleptic phosphino copper(i) complexes with in vitro and in vivo dual cytotoxic and anti-angiogenic activity

(2015) V. Gandin et al.   Metallomics

Targeting copper in cancer therapy: ‘Copper That Cancer’

(2015) Delphine Denoyer et al.   Metallomics

Cellular Transport Mechanisms of Cytotoxic Metallodrugs: An Overview beyond Cisplatin

(2014) Sarah Spreckelmeyer et al.   MOLECULES

Advances in Copper Complexes as Anticancer Agents

(2013) Carlo Santini et al.   CHEMICAL REVIEWS

ESTRA-FitEXA: A software package for EXAFS data analysis

(2012) C. Meneghini et al.   NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS

Synchrotron radiation X-ray absorption spectroscopic studies in solution and electrochemistry of a nitroimidazole conjugated heteroscorpionate copper(II) complex

(2012) Marco Giorgetti et al.   POLYHEDRON

Nitroimidazole and glucosamine conjugated heteroscorpionate ligands and related copper(ii) complexes. Syntheses, biological activity and XAS studies

(2011) Maura Pellei et al.   DALTON TRANSACTIONS

Treatment of human cancer cells with selenite or tellurite in combination with auranofin enhances cell death due to redox shift

(2009) Maria Pia Rigobello et al.   FREE RADICAL BIOLOGY AND MEDICINE

Copper in diseases and treatments, and copper-based anticancer strategies

(2009) Francesco Tisato et al.   MEDICINAL RESEARCH REVIEWS