Transcriptional Profiling of Th2 Cells Identifies Pathogenic Features Associated with Asthma

Differential gene expression analysis of peripheral blood mononuclear cells reveals novel test for early detection of pancreatic cancer

(2017) Michael J. Baine et al.   Cancer Biomarkers

eQTL of bronchial epithelial cells and bronchial alveolar lavage deciphers GWAS-identified asthma genes

(2015) X. Li et al.   ALLERGY

Interleukin-25 and mucosal T cells in noneosinophilic and eosinophilic chronic rhinosinusitis

(2015) Tomohisa Iinuma et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Taking T Cell Priming Down a Notch: Signaling through Notch Receptors Enhances T Cell Sensitivity to Antigen

(2015) Timothy J. Thauland et al.   IMMUNITY

Allergen-Induced Asthmatic Responses Modified by a GATA3-Specific DNAzyme

(2015) Norbert Krug et al.   NEW ENGLAND JOURNAL OF MEDICINE

PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation

(2015) Nikolaos Patsoukis et al.   Nature Communications

The differential characterization of GPR55 receptor in human peripheral blood reveals a distinctive expression in monocytes and NK cells and a proinflammatory role in these innate cells

(2014) Valerio Chiurchiù et al.   INTERNATIONAL IMMUNOLOGY

Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype

(2014) Manuel A.R. Ferreira et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Transcriptional Profile of Tuberculosis Antigen–Specific T Cells Reveals Novel Multifunctional Features

(2014) Cecilia Lindestam Arlehamn et al.   JOURNAL OF IMMUNOLOGY

Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex

(2014) Alex A Pollen et al.   NATURE BIOTECHNOLOGY

A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

(2014)   NATURE BIOTECHNOLOGY

Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility

(2014) Grégory Seumois et al.   NATURE IMMUNOLOGY

The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex

(2014) Emily B Heikamp et al.   NATURE IMMUNOLOGY

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

(2014) A. P. Patel et al.   SCIENCE

Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types

(2014) D. A. Jaitin et al.   SCIENCE

Allergic diseases and asthma: a global public health concern and a call to action

(2014) Ruby Pawankar   World Allergy Organization Journal

Narrative Review: The Role of Th2 Immune Pathway Modulation in the Treatment of Severe Asthma and Its Phenotypes

(2013) Stewart J. Levine   ANNALS OF INTERNAL MEDICINE

Transcriptome sequencing (RNA-Seq) of human endobronchial biopsies: asthmaversuscontrols

(2013) Ching Yong Yick et al.   EUROPEAN RESPIRATORY JOURNAL

NF-κB: roles and regulation in different CD4+T-cell subsets

(2013) Hyunju Oh et al.   IMMUNOLOGICAL REVIEWS

Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1

(2013) Chuan Wu et al.   NATURE

Pathogenic memory type Th2 cells in allergic inflammation

(2013) Yusuke Endo et al.   TRENDS IN IMMUNOLOGY

Prostaglandin E2 promotes Th1 differentiation via synergistic amplification of IL-12 signalling by cAMP and PI3-kinase

(2013) Chengcan Yao et al.   Nature Communications

Transcriptome analysis reveals upregulation of bitter taste receptors in severe asthmatics

(2012) Christina Orsmark-Pietras et al.   EUROPEAN RESPIRATORY JOURNAL

Allergic Rhinitis and its Impact on Asthma (ARIA): Achievements in 10 years and future needs

(2012) J. Bousquet et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The ConsensusPathDB interaction database: 2013 update

(2012) Atanas Kamburov et al.   NUCLEIC ACIDS RESEARCH

Protein Kinase CK2 Triggers Cytosolic Zinc Signaling Pathways by Phosphorylation of Zinc Channel ZIP7

(2012) K. M. Taylor et al.   Science Signaling

The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation

(2011) Ruoning Wang et al.   IMMUNITY

Eomesodermin Controls Interleukin-5 Production in Memory T Helper 2 Cells through Inhibition of Activity of the Transcription Factor GATA3

(2011) Yusuke Endo et al.   IMMUNITY

Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development

(2011) Gerritje J.W. van der Windt et al.   IMMUNITY

Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice

(2011) Sarah R. Walmsley et al.   JOURNAL OF CLINICAL INVESTIGATION

Coordinate Regulation of GATA-3 and Th2 Cytokine Gene Expression by the RNA-Binding Protein HuR

(2011) C. Stellato et al.   JOURNAL OF IMMUNOLOGY

Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ TH2 cells

(2011) Sabina A Islam et al.   NATURE IMMUNOLOGY

The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity

(2011) Mikyoung Chang et al.   NATURE IMMUNOLOGY

L-α-Lysophosphatidylinositol meets GPR55: a deadly relationship

(2011) Ruth A. Ross   TRENDS IN PHARMACOLOGICAL SCIENCES

Upregulation of IL17RB during Natural Allergen Exposure in Patients with Seasonal Allergic Rhinitis

(2011) Yuri Matsumoto et al.   ALLERGOLOGY INTERNATIONAL

Zinc signals promote IL-2-dependent proliferation of T cells

(2010) Jennifer Kaltenberg et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interferons Direct Th2 Cell Reprogramming to Generate a Stable GATA-3+T-bet+ Cell Subset with Combined Th2 and Th1 Cell Functions

(2010) Ahmed N. Hegazy et al.   IMMUNITY

A novel subset of CD4+TH2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma

(2010) Yui-Hsi Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chemokine Receptor 4 Plays a Key Role in T Cell Recruitment into the Airways of Asthmatic Patients

(2010) P. Vijayanand et al.   JOURNAL OF IMMUNOLOGY

Molecular Determinants of T Cell Epitope Recognition to the Common Timothy Grass Allergen

(2010) C. Oseroff et al.   JOURNAL OF IMMUNOLOGY

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

IL25 elicits a multipotent progenitor cell population that promotes TH2 cytokine responses

(2010) Steven A. Saenz et al.   NATURE

Role of GD3-CLIPR-59 Association in Lymphoblastoid T Cell Apoptosis Triggered by CD95/Fas

(2010) Maurizio Sorice et al.   PLoS One

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Essential role of the RNA-binding protein HuR in progenitor cell survival in mice

(2009) Mallika Ghosh et al.   JOURNAL OF CLINICAL INVESTIGATION

Zinc transporter ZIP8 (SLC39A8) and zinc influence IFN-γ expression in activated human T cells

(2009) Tolunay B. Aydemir et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Prostaglandin E2–EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion

(2009) Chengcan Yao et al.   NATURE MEDICINE

The NF- B Family of Transcription Factors and Its Regulation

(2009) A. Oeckinghaus et al.   Cold Spring Harbor Perspectives in Biology

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

ConsensusPathDB—a database for integrating human functional interaction networks

(2008) Atanas Kamburov et al.   NUCLEIC ACIDS RESEARCH