The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity

Smad7 and Smad6 bind to discrete regions of Pellino-1 via their MH2 domains to mediate TGF-β1-induced negative regulation of IL-1R/TLR signaling

(2010) Youn Sook Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulatory T cells: immune suppression and beyond

(2010) Yisong Y Wan   Cellular & Molecular Immunology

The roles of c-rel and interleukin-2 in tolerance: a molecular explanation of self-nonself discrimination

(2010) Hsiou-Chi Liou et al.   IMMUNOLOGY AND CELL BIOLOGY

Regulation of the IL-21 Gene by the NF- B Transcription Factor c-Rel

(2010) G. Chen et al.   JOURNAL OF IMMUNOLOGY

T Cell Activation

(2009) Jennifer E. Smith-Garvin et al.   Annual Review of Immunology

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Regulation of Th17 cell differentiation and EAE induction by MAP3K NIK

(2009) W. Jin et al.   BLOOD

c-Rel phenocopies PKCθ but not Bcl-10 in regulating CD8+T-cell activationversustolerance

(2009) Elissa K. Deenick et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Molecular orchestration of differentiation and function of regulatory T cells

(2009) L.-F. Lu et al.   GENES & DEVELOPMENT

NF- B1 p105 Regulates T Cell Homeostasis and Prevents Chronic Inflammation

(2009) M. Chang et al.   JOURNAL OF IMMUNOLOGY

New Insights into the Molecular Basis of T Cell Anergy: Anergy Factors, Avoidance Sensors, and Epigenetic Imprinting

(2009) A. D. Wells   JOURNAL OF IMMUNOLOGY

Ubiquitylation in innate and adaptive immunity

(2009) Vijay G. Bhoj et al.   NATURE

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production

(2009) Mikyoung Chang et al.   NATURE IMMUNOLOGY

Selectivity of the NF- B Response

(2009) R. Sen et al.   Cold Spring Harbor Perspectives in Biology

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

Negative regulation of lymphocyte development and function by the Cbl family of proteins

(2008) Fang Huang et al.   IMMUNOLOGICAL REVIEWS

Mechanisms of regulatory T-cell suppression – a diverse arsenal for a moving target

(2008) Dorothy K. Sojka et al.   IMMUNOLOGY

cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination

(2008) Mathieu J.M. Bertrand et al.   MOLECULAR CELL

The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling

(2008) Paul N. Moynagh   TRENDS IN IMMUNOLOGY

The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1

(2007) Alban Ordureau et al.   BIOCHEMICAL JOURNAL