Astragaloside IV regulates the ferroptosis signaling pathway via the Nrf2/SLC7A11/GPX4 axis to inhibit PM2.5-mediated lung injury in mice

Sipeimine ameliorates PM2.5-induced lung injury by inhibiting ferroptosis via the PI3K/Akt/Nrf2 pathway: A network pharmacology approach

(2022) Yilan Wang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Astragaloside IV Protects from PM2.5-Induced Lung Injury by Regulating Autophagy via Inhibition of PI3K/Akt/mTOR Signaling in vivo and in vitro

(2021) Caixia Pei et al.   Journal of Inflammation Research

Melatonin protects against PM2.5-induced lung injury by inhibiting ferroptosis of lung epithelial cells in a Nrf2-dependent manner

(2021) Fan Guohua et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Ferrostatin-1 alleviates lipopolysaccharide-induced acute lung injury via inhibiting ferroptosis

(2020) Pengfei Liu et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Independent and Combined Effects of Heatwaves and PM2.5 on Preterm Birth in Guangzhou, China: A Survival Analysis

(2020) Qiong Wang et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Lipid peroxidation and ferroptosis: The role of GSH and GPx4

(2020) Fulvio Ursini et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nrf2 inhibits ferroptosis and protects against acute lung injury due to intestinal ischemia reperfusion via regulating SLC7A11 and HO-1

(2020) Hui Dong et al.   Aging-US

Identification of two novel prenylated flavonoids in mulberry leaf and their bioactivities

(2020) Lingrong Wen et al.   FOOD CHEMISTRY

Ginkgetin derived from Ginkgo biloba leaves enhances the therapeutic effect of cisplatin via ferroptosis-mediated disruption of the Nrf2/HO-1 axis in EGFR wild-type non-small-cell lung cancer

(2020) Jian-Shu Lou et al.   PHYTOMEDICINE

Astragaloside IV alleviates PM2.5-induced lung injury in rats by modulating TLR4/MyD88/NF-κB signalling pathway

(2020) Yongcan Wu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

ROS-Responsive Nanoparticles for Suppressing the Cytotoxicity and Immunogenicity Caused by PM2.5 Particulates

(2019) Yixian Zhang et al.   BIOMACROMOLECULES

The Role of Astragaloside IV against Cerebral Ischemia/Reperfusion Injury: Suppression of Apoptosis via Promotion of P62-LC3-Autophagy

(2019) Yi Zhang et al.   MOLECULES

ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway

(2019) Bo Chu et al.   NATURE CELL BIOLOGY

ATF3 promotes erastin-induced ferroptosis by suppressing system Xc–

(2019) Liyuan Wang et al.   CELL DEATH AND DIFFERENTIATION

PM2.5 induces ferroptosis in human endothelial cells through iron overload and redox imbalance

(2019) Yan Wang et al.   ENVIRONMENTAL POLLUTION

PM2.5 induces EMT and promotes CSC properties by activating Notch pathway in vivo and vitro

(2019) Yunxia Wang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Particulate matter-induced senescence of skin keratinocytes involves oxidative stress-dependent epigenetic modifications

(2019) Yea Seong Ryu et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Ferroptosis caused by cysteine insufficiency and oxidative insult

(2019) Junichi Fujii et al.   FREE RADICAL RESEARCH

Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis

(2019) Lian-Jiu Su et al.   Oxidative Medicine and Cellular Longevity

ROS-mediated autophagy increases intracellular iron levels and ferroptosis by ferritin and transferrin receptor regulation

(2019) Eunhee Park et al.   Cell Death & Disease

Peroxiredoxin-1 regulates lipid peroxidation in corneal endothelial cells

(2019) Matthew Lovatt et al.   Redox Biology

Erastin Inhibits Septic Shock and Inflammatory Gene Expression via Suppression of the NF-κB Pathway

(2019) Byung Moo Oh et al.   Journal of Clinical Medicine

Brain mitochondrial iron accumulates in Huntington's disease, mediates mitochondrial dysfunction, and can be removed pharmacologically

(2018) Sonal Agrawal et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ferroptosis-inducing agents compromise in vitro human islet viability and function

(2018) Antonio Bruni et al.   Cell Death & Disease

YiQiFuMai lyophilized injection attenuates particulate matter-induced acute lung injury in mice via TLR4-mTOR-autophagy pathway

(2018) Yuanli Xia et al.   BIOMEDICINE & PHARMACOTHERAPY

Outdoor Particulate Matter Exposure and Lung Cancer: A Systematic Review and Meta-Analysis

(2018) Ghassan B. Hamra et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Increased Iron Levels and Decreased Tissue Integrity in Hippocampus of Alzheimer's Disease Detected in vivo with Magnetic Resonance Imaging

(2018) Erika P. Raven et al.   JOURNAL OF ALZHEIMERS DISEASE

Astragaloside IV Attenuates Acetaminophen-Induced Liver Injuries in Mice by Activating the Nrf2 Signaling Pathway

(2018) Lei Li et al.   MOLECULES

Polyphenols from Acorn Leaves (Quercus liaotungensis) Protect Pancreatic Beta Cells and Their Inhibitory Activity against α-Glucosidase and Protein Tyrosine Phosphatase 1B

(2018) Jing Xu et al.   MOLECULES

Prolonged PM2.5 exposure elevates risk of oxidative stress-driven nonalcoholic fatty liver disease by triggering increase of dyslipidemia

(2018) Min-Xuan Xu et al.   FREE RADICAL BIOLOGY AND MEDICINE

PM2.5-induced lung inflammation in mice: Differences of inflammatory response in macrophages and type II alveolar cells

(2017) Miao He et al.   JOURNAL OF APPLIED TOXICOLOGY

NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis

(2017) Samantha W. Alvarez et al.   NATURE

Cysteine Dioxygenase 1 Mediates Erastin-Induced Ferroptosis in Human Gastric Cancer Cells

(2017) Shihui Hao et al.   NEOPLASIA

Insulin sensitizers prevent fine particulate matter-induced vascular insulin resistance and changes in endothelial progenitor cell homeostasis

(2016) Petra Haberzettl et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Retraction: Decline in NRF2-regulated Antioxidants in Chronic Obstructive Pulmonary Disease Lungs Due to Loss of Its Positive Regulator, DJ-1; Heightened Endoplasmic Reticulum Stress in the Lungs of Patients with Chronic Obstructive Pulmonary Disease: The Role of Nrf2-Regulated Proteasomal Activity

(2016)   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Development of two fine particulate matter standard reference materials (

(2016) Michele M. Schantz et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

Inhibitory Effects of Astragaloside IV on Bleomycin-Induced Pulmonary Fibrosis in Rats Via Attenuation of Oxidative Stress and Inflammation

(2016) Wei-Na Yu et al.   INFLAMMATION

Elemental characterization and source apportionment of PM 10 and PM 2.5 in the western coastal area of central Taiwan

(2016) Chin-Yu Hsu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Differences in allergic inflammatory responses between urban PM2.5 and fine particle derived from desert-dust in murine lungs

(2016) Miao He et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Glutaminolysis and Transferrin Regulate Ferroptosis

(2015) Minghui Gao et al.   MOLECULAR CELL

Usnic acid protects LPS-induced acute lung injury in mice through attenuating inflammatory responses and oxidative stress

(2014) Zu-Qing Su et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Transcriptional responses of neonatal mouse lung to hyperoxia by Nrf2 status

(2013) Sharon A. McGrath-Morrow et al.   CYTOKINE

The role of iron and reactive oxygen species in cell death

(2013) Scott J Dixon et al.   Nature Chemical Biology

Endotoxin in concentrated coarse and fine ambient particles induces acute systemic inflammation in controlled human exposures

(2013) Behrooz Behbod et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

The Cystine/Glutamate Antiporter System xc− in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities

(2012) Jan Lewerenz et al.   ANTIOXIDANTS & REDOX SIGNALING

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

System xc- cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS

(2011) Richard J Bridges et al.   BRITISH JOURNAL OF PHARMACOLOGY

In vitrotoxicology of ambient particulate matter: Correlation of cellular effects with particle size and components

(2011) Alexandra Kroll et al.   ENVIRONMENTAL TOXICOLOGY

Role of sulforaphane in the anti-initiating mechanism of lung carcinogenesis in vivo by modulating the metabolic activation and detoxification of benzo(a)pyrene

(2010) D. Kalpana Deepa Priya et al.   BIOMEDICINE & PHARMACOTHERAPY

Roles of oxidative stress in signaling and inflammation induced by particulate matter

(2010) Flavia Mazzoli-Rocha et al.   CELL BIOLOGY AND TOXICOLOGY