Activation of inflammasome signaling mediates pathology of acute P. aeruginosa pneumonia

IL-18 Induces Emphysema and Airway and Vascular Remodeling via IFN-γ, IL-17A, and IL-13

(2012) Min-Jong Kang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria

(2012) Vijay A.K. Rathinam et al.   CELL

NLRC4 Inflammasome-Mediated Production of IL-1  Modulates Mucosal Immunity in the Lung against Gram-Negative Bacterial Infection

(2012) S. Cai et al.   JOURNAL OF IMMUNOLOGY

Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

(2012) Petr Broz et al.   NATURE

Induction of Type I Interferon Signaling byPseudomonas aeruginosaIs Diminished in Cystic Fibrosis Epithelial Cells

(2011) Dane Parker et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

(2011) Greta Guarda et al.   IMMUNITY

Receptor-Interacting Protein 2 Controls Pulmonary Host Defense to Escherichia coli Infection via the Regulation of Interleukin-17A

(2011) Theivanthiran Balamayooran et al.   INFECTION AND IMMUNITY

Participation of CD11c+Leukocytes in Methicillin-Resistant Staphylococcus aureus Clearance from the Lung

(2011) Francis J. Martin et al.   INFECTION AND IMMUNITY

Interleukin-23-Mediated Inflammation in Pseudomonas aeruginosa Pulmonary Infection

(2011) Patricia J. Dubin et al.   INFECTION AND IMMUNITY

Role of Toll Interleukin-1 Receptor (IL-1R) 8, a Negative Regulator of IL-1R/Toll-Like Receptor Signaling, in Resistance to Acute Pseudomonas aeruginosa Lung Infection

(2011) Tania Véliz Rodriguez et al.   INFECTION AND IMMUNITY

Mycobacterium tuberculosis Triggers Host Type I IFN Signaling To Regulate IL-1  Production in Human Macrophages

(2011) A. Novikov et al.   JOURNAL OF IMMUNOLOGY

The Interaction between IL-18 and IL-18 Receptor Limits the Magnitude of Protective Immunity and Enhances Pathogenic Responses following Infection with Intracellular Bacteria

(2011) P. Ghose et al.   JOURNAL OF IMMUNOLOGY

IL-1  and IL-1  Recruit Different Myeloid Cells and Promote Different Stages of Sterile Inflammation

(2011) P. Rider et al.   JOURNAL OF IMMUNOLOGY

Differential effects of kidney–lung cross-talk during acute kidney injury and bacterial pneumonia

(2011) Kai Singbartl et al.   KIDNEY INTERNATIONAL

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

(2011) Yue Zhao et al.   NATURE

Streptococcus pneumoniae DNA Initiates Type I Interferon Signaling in the Respiratory Tract

(2011) D. Parker et al.   mBio

Inflammasome-dependent Pyroptosis and IL-18 Protect against Burkholderia pseudomallei Lung Infection while IL-1β Is Deleterious

(2011) Ivonne Ceballos-Olvera et al.   PLoS Pathogens

Pseudomonas aeruginosa pilin activates the inflammasome

(2010) Cecilia S. Lindestam Arlehamn et al.   CELLULAR MICROBIOLOGY

In Vivo Discrimination of Type 3 Secretion System-Positive and -Negative Pseudomonas aeruginosa via a Caspase-1-Dependent Pathway

(2010) T. Wangdi et al.   INFECTION AND IMMUNITY

IFN Regulatory Factor 3 Contributes to the Host Response during Pseudomonas aeruginosa Lung Infection in Mice

(2010) S. O. Carrigan et al.   JOURNAL OF IMMUNOLOGY

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

(2010) Edward A Miao et al.   NATURE IMMUNOLOGY

Role of Toll-like receptor 5 in the innate immune response to acute P. aeruginosa pneumonia

(2009) Amy E. Morris et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Epilysin (MMP-28) Restrains Early Macrophage Recruitment in Pseudomonas aeruginosa Pneumonia

(2009) A. M. Manicone et al.   JOURNAL OF IMMUNOLOGY

Identification of Host Cytosolic Sensors and Bacterial Factors Regulating the Type I Interferon Response to Legionella pneumophila

(2009) Kathryn M. Monroe et al.   PLoS Pathogens

Effect of IL-10 on Neutrophil Recruitment and Survival afterPseudomonas aeruginosaChallenge

(2008) Lei Sun et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Cell death in the host response to infection

(2008) K Labbé et al.   CELL DEATH AND DIFFERENTIATION

Increased mortality of ventilated patients with endotracheal Pseudomonas aeruginosa without clinical signs of infection*

(2008) Hanjing Zhuo et al.   CRITICAL CARE MEDICINE

IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

(2008) Shean J Aujla et al.   NATURE MEDICINE

Pseudomonas aeruginosa activates caspase 1 through Ipaf

(2008) E. A. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms

(2008) S. L. Fink et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA