Epigenetic and Transcriptional Regulation of IRAK-M Expression in Macrophages

Induction of Siglec-1 by Endotoxin Tolerance Suppresses the Innate Immune Response by Promoting TGF-β1 Production

(2016) Yin Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Subclinical-Dose Endotoxin Sustains Low-Grade Inflammation and Exacerbates Steatohepatitis in High-Fat Diet–Fed Mice

(2016) Honghui Guo et al.   JOURNAL OF IMMUNOLOGY

Sirtuins Link Inflammation and Metabolism

(2016) Vidula T. Vachharajani et al.   Journal of Immunology Research

Chronic Toxicity and Carcinogenicity Studies of the Long-Acting GLP-1 Receptor Agonist Dulaglutide in Rodents

(2015) Richard A. Byrd et al.   ENDOCRINOLOGY

Coordinated Regulation of miR-155 and miR-146a Genes during Induction of Endotoxin Tolerance in Macrophages

(2015) Christina Doxaki et al.   JOURNAL OF IMMUNOLOGY

IRAK-M Deficiency Promotes the Development of Type 1 Diabetes in NOD Mice

(2014) Q. Tan et al.   DIABETES

Epigenetic coordination of acute systemic inflammation: potential therapeutic targets

(2014) Vidula Vachharajani et al.   Expert Review of Clinical Immunology

A Distal Locus Element Mediates IFN-γ Priming of Lipopolysaccharide-Stimulated TNF Gene Expression

(2014) Nancy A. Chow et al.   Cell Reports

Transcriptional Regulation and Its Misregulation in Disease

(2013) Tong Ihn Lee et al.   CELL

Training innate immunity: the changing concept of immunological memory in innate host defence

(2013) Mihai G. Netea   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Akt2 Deficiency Protects from Acute Lung Injury via Alternative Macrophage Activation and miR-146a Induction in Mice

(2013) E. Vergadi et al.   JOURNAL OF IMMUNOLOGY

Targeted disruption of the EZH2–EED complex inhibits EZH2-dependent cancer

(2013) Woojin Kim et al.   Nature Chemical Biology

PPAR Agonist-Induced Reduction of Mcp1 in Atherosclerotic Plaques of Obese, Insulin-Resistant Mice Depends on Adiponectin-Induced Irak3 Expression

(2013) Maarten Hulsmans et al.   PLoS One

Transcription of Tnfaip3 Is Regulated by NF-κB and p38 via C/EBPβ in Activated Macrophages

(2013) Ting-Yu Lai et al.   PLoS One

The E3 Ubiquitin Ligase Neuregulin Receptor Degradation Protein 1 (Nrdp1) Promotes M2 Macrophage Polarization by Ubiquitinating and Activating Transcription Factor CCAAT/Enhancer-binding Protein β (C/EBPβ)

(2012) Shuo Ye et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interleukin 1 Receptor–Associated Kinase M Impairs Host Defense During Pneumococcal Pneumonia

(2012) Gerritje J. W. van der Windt et al.   JOURNAL OF INFECTIOUS DISEASES

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(2012) Jacobien Hoogerwerf et al.   MOLECULAR MEDICINE

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

(2012) Laurens Kruidenier et al.   NATURE

Interleukin-1 Receptor-Associated Kinase-3 Is a Key Inhibitor of Inflammation in Obesity and Metabolic Syndrome

(2012) Maarten Hulsmans et al.   PLoS One

Interleukin-1 Receptor-Associated Kinase 2- and Protein Kinase D1-Dependent Regulation of IRAK-Monocyte Expression by CpG DNA

(2012) Young-In Kim et al.   PLoS One

Ectopic expression of the histone methyltransferase Ezh2 in haematopoietic stem cells causes myeloproliferative disease

(2012) A. Herrera-Merchan et al.   Nature Communications

Interleukin-1 receptor-associated kinase-M suppresses systemic lupus erythematosus

(2011) M. Lech et al.   ANNALS OF THE RHEUMATIC DISEASES

IL-13 dampens human airway epithelial innate immunity through induction of IL-1 receptor–associated kinase M

(2011) Qun Wu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

NAD+-dependent SIRT1 Deacetylase Participates in Epigenetic Reprogramming during Endotoxin Tolerance

(2011) Tie Fu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

Facultative heterochromatin formation at the IL-1 beta promoter in LPS tolerance and sepsis

(2010) Barbara K. Yoza et al.   CYTOKINE

UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis

(2010) Shayesta Seenundun et al.   EMBO JOURNAL

Tumor-Induced Tolerance and Immune Suppression Depend on the C/EBPβ Transcription Factor

(2010) Ilaria Marigo et al.   IMMUNITY

Maintaining Cell Identity through Global Control of Genomic Organization

(2010) Gioacchino Natoli   IMMUNITY

SMAD4 Is Required for Development of Maximal Endotoxin Tolerance

(2010) H. Pan et al.   JOURNAL OF IMMUNOLOGY

Gene-Specific Epigenetic Regulation in Serious Infections with Systemic Inflammation

(2010) Charles E. McCall et al.   Journal of Innate Immunity

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Biochemical mechanisms of gene regulation by polycomb group protein complexes

(2009) Jürg Müller et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Dynamic and Selective Nucleosome Repositioning during Endotoxin Tolerance

(2009) Mohamed El Gazzar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adiponectin Promotes Endotoxin Tolerance in Macrophages by Inducing IRAK-M Expression

(2009) Vassiliki Zacharioudaki et al.   JOURNAL OF IMMUNOLOGY

Critical Role of IL-1 Receptor-Associated Kinase-M in Regulating Chemokine-Dependent Deleterious Inflammation in Murine Influenza Pneumonia

(2009) M. Seki et al.   JOURNAL OF IMMUNOLOGY

Differential Role for c-Rel and C/EBP /  in TLR-Mediated Induction of Proinflammatory Cytokines

(2009) Y.-C. Lu et al.   JOURNAL OF IMMUNOLOGY

A CREB-C/EBP  cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair

(2009) D. Ruffell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA