Ectopic expression of the histone methyltransferase Ezh2 in haematopoietic stem cells causes myeloproliferative disease
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Ectopic expression of the histone methyltransferase Ezh2 in haematopoietic stem cells causes myeloproliferative disease
Authors
Keywords
-
Journal
Nature Communications
Volume 3, Issue 1, Pages -
Publisher
Springer Nature
Online
2012-01-10
DOI
10.1038/ncomms1623
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Polycomb complex PRC2 and its mark in life
- (2011) Raphaël Margueron et al. NATURE
- Clinical Effect of Point Mutations in Myelodysplastic Syndromes
- (2011) Rafael Bejar et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mechanisms controlling hematopoietic stem cell functions during normal hematopoiesis and hematological malignancies
- (2011) Matthew R. Warr et al. Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- Overexpression of the EZH2, RING1 and BMI1 genes is common in myelodysplastic syndromes: relation to adverse epigenetic alteration and poor prognostic scoring
- (2010) Feng Xu et al. ANNALS OF HEMATOLOGY
- Polycomb proteins in hematologic malignancies
- (2010) D. Martin-Perez et al. BLOOD
- Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus
- (2010) Q. Li et al. BLOOD
- Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
- (2010) D. B. Yap et al. BLOOD
- Signatures of polycomb repression and reduced H3K4 trimethylation are associated with p15INK4b DNA methylation in AML
- (2010) T. A. Paul et al. BLOOD
- Physiological Jak2V617F Expression Causes a Lethal Myeloproliferative Neoplasm with Differential Effects on Hematopoietic Stem and Progenitor Cells
- (2010) Ann Mullally et al. CANCER CELL
- Mechanistic principles of chromatin remodeling guided by siRNAs and miRNAs
- (2010) Susana Gonzalez et al. CELL CYCLE
- miR-33-mediated downregulation of p53 controls hematopoietic stem cell self-renewal
- (2010) Antonio Herrera-Merchan et al. CELL CYCLE
- Polycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer
- (2010) Martin Sauvageau et al. Cell Stem Cell
- Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes
- (2010) Gorica Nikoloski et al. NATURE GENETICS
- Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
- (2010) Ryan D Morin et al. NATURE GENETICS
- Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
- (2010) Thomas Ernst et al. NATURE GENETICS
- Molecular Signatures of Quiescent, Mobilized and Leukemia-Initiating Hematopoietic Stem Cells
- (2010) E. Camilla Forsberg et al. PLoS One
- Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas
- (2010) C. J. Sneeringer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulating the leukaemia stem cell
- (2009) Michael L. Cleary BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY
- Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells
- (2009) W. Fiskus et al. BLOOD
- EVI-1 interacts with histone methyltransferases SUV39H1 and G9a for transcriptional repression and bone marrow immortalization
- (2009) S Goyama et al. LEUKEMIA
- Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells
- (2008) W. F. Tam et al. BLOOD
- Evi-1 Is a Critical Regulator for Hematopoietic Stem Cells and Transformed Leukemic Cells
- (2008) Susumu Goyama et al. Cell Stem Cell
- An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors
- (2008) Ittai Ben-Porath et al. NATURE GENETICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search