Irisin and ALCAT1 mediated aerobic exercise-alleviated oxidative stress and apoptosis in skeletal muscle of mice with myocardial infarction

Pharmacological inhibition of ALCAT1 mitigates amyotrophic lateral sclerosis by attenuating SOD1 protein aggregation

(2022) Xueling Liu et al.   Molecular Metabolism

Mechanisms of muscle atrophy and hypertrophy: implications in health and disease

(2021) Roberta Sartori et al.   Nature Communications

Systemic oxidative stress is associated with lower aerobic capacity and impaired skeletal muscle energy metabolism in heart failure patients

(2021) Takashi Yokota et al.   Scientific Reports

Exercise Training Enhances Myocardial Mitophagy and Improves Cardiac Function via Irisin/FNDC5-PINK1/Parkin Pathway in MI Mice

(2021) Hangzhuo Li et al.   Biomedicines

Aerobic exercise and resistance exercise alleviate skeletal muscle atrophy through IGF-1/IGF-1R-PI3K/Akt pathway in mice with myocardial infarction

(2021) Lili Feng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The Roles of FGF21 and ALCAT1 in Aerobic Exercise-Induced Cardioprotection of Postmyocardial Infarction Mice

(2021) Wenyan Bo et al.   Oxidative Medicine and Cellular Longevity

Sarcopenia and Heart Failure

(2020) Francesco Curcio et al.   Nutrients

Impacts of rat hind-limb Fndc5/Irisin overexpression upon muscle and adipose tissue metabolism

(2020) Wesam Farrash et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Inhibition of xanthine oxidase in the acute phase of myocardial infarction prevents skeletal muscle abnormalities and exercise intolerance

(2020) Hideo Nambu et al.   CARDIOVASCULAR RESEARCH

The effect of nutrition and exercise training on irisin and semaphorin-3E levels in obese patients

(2020) Gülay Sezgin et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Aerobic exercise alleviates oxidative stress-induced apoptosis in kidneys of myocardial infarction mice by inhibiting ALCAT1 and activating FNDC5/Irisin signaling pathway

(2020) Fangnan Wu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Muscle Wasting and Sarcopenia in Heart Failure—The Current State of Science

(2020) Alessia Lena et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exercise as a Therapeutic Strategy for Sarcopenia in Heart Failure: Insights into Underlying Mechanisms

(2020) Jinkyung Cho et al.   Cells

Cardiolipin remodeling by ALCAT1 links mitochondrial dysfunction to Parkinson’s diseases

(2019) Chengjie Song et al.   AGING CELL

Irisin attenuates oxidized low‐density lipoprotein impaired angiogenesis through AKT/mTOR/S6K1/Nrf2 pathway

(2019) Min Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

ALCAT1 Overexpression Affects Supercomplex Formation and Increases ROS in Respiring Mitochondria

(2019) Bettina Rieger et al.   Oxidative Medicine and Cellular Longevity

Interval exercise training increases LIF expression and prevents myocardial infarction-induced skeletal muscle atrophy in rats

(2018) Dandan Jia et al.   LIFE SCIENCES

Effects of different types of exercise on skeletal muscle atrophy, antioxidant capacity and growth factors expression following myocardial infarction

(2018) Mengxin Cai et al.   LIFE SCIENCES

Exercise training decreases NADPH oxidase activity and restores skeletal muscle mass in heart failure rats

(2017) Telma F. Cunha et al.   JOURNAL OF APPLIED PHYSIOLOGY

Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy

(2017) Musarrat Maisha Reza et al.   Nature Communications

Benefits of lifelong exercise training on left ventricular function after myocardial infarction

(2017) Martijn FH Maessen et al.   European Journal of Preventive Cardiology

Redox control of skeletal muscle atrophy

(2016) Scott K. Powers et al.   FREE RADICAL BIOLOGY AND MEDICINE

Irisin, a novel myokine is an independent predictor for sarcopenia and carotid atherosclerosis in dialysis patients

(2015) Mi Jung Lee et al.   ATHEROSCLEROSIS

Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes

(2015) T.-Y. Liu et al.   CLINICAL SCIENCE

ALCAT1 controls mitochondrial etiology of fatty liver diseases, linking defective mitophagy to steatosis

(2015) Li Wang et al.   HEPATOLOGY

Irisin, a Novel Myokine, Regulates Glucose Uptake in Skeletal Muscle Cells via AMPK

(2015) Hye Jeong Lee et al.   MOLECULAR ENDOCRINOLOGY

Fibronectin type III domain containing 5 expression in skeletal muscle in chronic heart failure-relevance of inflammatory cytokines

(2015) Yae Matsuo et al.   Journal of Cachexia Sarcopenia and Muscle

Leptin administration activates irisin-induced myogenesis via nitric oxide-dependent mechanisms, but reduces its effect on subcutaneous fat browning in mice

(2014) A Rodríguez et al.   INTERNATIONAL JOURNAL OF OBESITY

AICAR stimulation metabolome widely mimics electrical contraction in isolated rat epitrochlearis muscle

(2013) Licht Miyamoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The effects of chronic muscle use and disuse on cardiolipin metabolism

(2012) Olga Ostojić et al.   JOURNAL OF APPLIED PHYSIOLOGY

Ablation of ALCAT1 Mitigates Hypertrophic Cardiomyopathy through Effects on Oxidative Stress and Mitophagy

(2012) X. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

Exercise Training Prevents Oxidative Stress and Ubiquitin-Proteasome System Overactivity and Reverse Skeletal Muscle Atrophy in Heart Failure

(2012) Telma F. Cunha et al.   PLoS One

Lysocardiolipin acyltransferase 1 (ALCAT1) controls mitochondrial DNA fidelity and biogenesis through modulation of MFN2 expression

(2012) J. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiolipin Remodeling by ALCAT1 Links Oxidative Stress and Mitochondrial Dysfunction to Obesity

(2010) Jia Li et al.   Cell Metabolism

The microsomal cardiolipin remodeling enzyme acyl-CoA lysocardiolipin acyltransferase is an acyltransferase of multiple anionic lysophospholipids

(2008) Yang Zhao et al.   JOURNAL OF LIPID RESEARCH