Microplastics and di (2-ethylhexyl) phthalate synergistically induce apoptosis in mouse pancreas through the GRP78/CHOP/Bcl-2 pathway activated by oxidative stress

The antagonistic effect of selenium on lead-induced apoptosis and necroptosis via P38/JNK/ERK pathway in chicken kidney

(2022) Zhiruo Miao et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

TMT induces apoptosis and necroptosis in mouse kidneys through oxidative stress-induced activation of the NLRP3 inflammasome

(2022) Xiao-Jing Liu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Tea polyphenols alleviates acetochlor-induced apoptosis and necroptosis via ROS/MAPK/NF-κB signaling in Ctenopharyngodon idellus kidney cells

(2022) Xia Zhao et al.   AQUATIC TOXICOLOGY

Polystyrene nanoplastics induced cardiomyocyte apoptosis and myocardial inflammation in carp by promoting ROS production

(2022) Hao Wu et al.   FISH & SHELLFISH IMMUNOLOGY

Selenoprotein K protects skeletal muscle from damage and is required for satellite cells-mediated myogenic differentiation

(2022) Shengchen Wang et al.   Redox Biology

MiR-1656 targets GPX4 to trigger pyroptosis in broilers kidney tissues by activating NLRP3 inflammasome under Se deficiency

(2022) Xuedie Gu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Polystyrene microplastics lead to pyroptosis and apoptosis of ovarian granulosa cells via NLRP3/Caspase-1 signaling pathway in rats

(2021) Junyu Hou et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Polystyrene microplastics induce blood–testis barrier disruption regulated by the MAPK-Nrf2 signaling pathway in rats

(2021) Shengda Li et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Rosmarinic acid attenuates acrylamide induced apoptosis of BRL-3A cells by inhibiting oxidative stress and endoplasmic reticulum stress

(2021) Zhuang Hong et al.   FOOD AND CHEMICAL TOXICOLOGY

Effects of microplastics (MPs) and tributyltin (TBT) alone and in combination on bile acids and gut microbiota crosstalk in mice

(2021) Ping Jiang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Adverse effect of polystyrene microplastics (PS-MPs) on tube formation and viability of human umbilical vein endothelial cells

(2021) Hee-Seop Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

Polystyrene microplastics trigger hepatocyte apoptosis and abnormal glycolytic flux via ROS-driven calcium overload

(2021) Siwen Li et al.   JOURNAL OF HAZARDOUS MATERIALS

Microplastics as an emerging source of particulate air pollution: A critical review

(2021) Srinidhi Sridharan et al.   JOURNAL OF HAZARDOUS MATERIALS

Polystyrene microplastics-induced ROS overproduction disrupts the skeletal muscle regeneration by converting myoblasts into adipocytes

(2021) Wang Shengchen et al.   JOURNAL OF HAZARDOUS MATERIALS

Impact of high salt diets on CHOP-mediated apoptosis and renal fibrosis in a rat model

(2021) Tooka Khadive et al.   MOLECULAR BIOLOGY REPORTS

New insights into crosstalk between apoptosis and necroptosis co-induced by chlorothalonil and imidacloprid in Ctenopharyngodon idellus kidney cells

(2021) Xiaojing Li et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Cadmium induces endoplasmic reticulum stress-mediated apoptosis in pig pancreas via the increase of Th1 cells

(2021) Hao Wu et al.   TOXICOLOGY

Exposure to Stearate Activates the IRE1α/XBP-1 Pathway in 3T3-L1 Adipocytes

(2021) Yoshihiro Takeda et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

H2S exposure induces cell death in the broiler thymus via the ROS-initiated JNK/MST1/FOXO1 pathway

(2021) Qianru Chi et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

The novel role of the aquaporin water channel in lycopene preventing DEHP-induced renal ionic homeostasis disturbance in mice

(2021) Fu-Wei Jiang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Exposure to DEHP induces testis toxicity and injury through the ROS/mTOR/NLRP3 signaling pathway in immature rats

(2021) Yifan Hong et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Pig lung fibrosis is active in the subacute CdCl2 exposure model and exerts cumulative toxicity through the M1/M2 imbalance

(2021) Shi Xu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Exposure to imidacloprid induce oxidative stress, mitochondrial dysfunction, inflammation, apoptosis and mitophagy via NF-kappaB/JNK pathway in grass carp hepatocytes

(2021) Zhiruo Miao et al.   FISH & SHELLFISH IMMUNOLOGY

Lycopene Preventing DEHP-Induced Renal Cell Damage Is Targeted by Aryl Hydrocarbon Receptor

(2021) Mu-Zi Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Distribution and sedimentation of microplastics in Taihu Lake

(2021) Qiji Zhang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Occurrence, distribution and affecting factors of microplastics in agricultural soils along the lower reaches of Yangtze River, China

(2021) Lu Cao et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Chronic cadmium exposure induces epithelial mesenchymal transition in prostate cancer cells through a TGF-β-independent, endoplasmic reticulum stress induced pathway

(2021) Weirong Hu et al.   TOXICOLOGY LETTERS

Potential environmental risk assessment of di-2-ethylhexyl phthalate emissions from a municipal solid waste landfill leachate

(2021) Paweł Wowkonowicz et al.   PeerJ

Bladder cancer: total antioxidant capacity and pharmacotherapy with vitamin-E

(2020) Hamid Mazdak et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

Environmentally-relevant exposure to diethylhexyl phthalate (DEHP) alters regulation of double-strand break formation and crossover designation leading to germline dysfunction in Caenorhabditis elegans

(2020) Luciann Cuenca et al.   PLoS Genetics

Calreticulin regulated intrinsic apoptosis through mitochondria-dependent and independent pathways mediated by ER stress in arsenite exposed HT-22 cells

(2020) Xiaotong Wang et al.   CHEMOSPHERE

Endolysosomal Targeting of Mitochondria Is Integral to BAX-Mediated Mitochondrial Permeabilization during Apoptosis Signaling

(2020) Tim Sen Wang et al.   DEVELOPMENTAL CELL

Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats

(2020) Ru An et al.   TOXICOLOGY

VEGF-A promotes angiogenesis after acute myocardial infarction through increasing ROS production and enhancing ER stress-mediated autophagy

(2019) Jiang Zou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Methylmercury exposure induces ROS/Akt inactivation-triggered endoplasmic reticulum stress-regulated neuronal cell apoptosis

(2019) Yao-Pang Chung et al.   TOXICOLOGY

eIF2α-CHOP-BCl-2/JNK and IRE1α-XBP1/JNK signaling promote apoptosis and inflammation and support the proliferation of Newcastle disease virus

(2019) Yanrong Li et al.   Cell Death & Disease

Single and mixture toxicity of strobilurin and SDHI fungicides to Xenopus tropicalis embryos

(2018) Siyu Wu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Down-regulation of GRP78 alleviates lipopolysaccharide-induced acute kidney injury

(2018) Jinlong Teng et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

Di (2-ethylhexyl) phthalate (DEHP) alters proliferation and uterine gland numbers in the uteri of adult exposed mice

(2018) Kadeem A. Richardson et al.   REPRODUCTIVE TOXICOLOGY

Gestational di-(2-ethylhexyl) phthalate exposure causes fetal intrauterine growth restriction through disturbing placental thyroid hormone receptor signaling

(2018) Zhen Yu et al.   TOXICOLOGY LETTERS

Evidence that the Great Pacific Garbage Patch is rapidly accumulating plastic

(2018) L. Lebreton et al.   Scientific Reports

Association Between Diethylhexyl Phthalate Exposure and Thyroid Function: A Meta-Analysis

(2018) Min Joo Kim et al.   THYROID

Simulated digestion of polystyrene foam enhances desorption of diethylhexyl phthalate (DEHP) and In vitro estrogenic activity in a size-dependent manner

(2018) Scott Coffin et al.   ENVIRONMENTAL POLLUTION

Cigarette smoke extract and isoprene resulted in the induction of apoptosis and autophagy in human placenta choriocarcinoma JEG-3 cells

(2017) Hae-Miru Lee et al.   ENVIRONMENTAL TOXICOLOGY

GRP78 silencing enhances hyperoxia-induced alveolar epithelial cell apoptosis via CHOP pathway

(2017) Hong-Yan Lu et al.   Molecular Medicine Reports

Production, use, and fate of all plastics ever made

(2017) Roland Geyer et al.   Science Advances

The Role of the PERK/eIF2α/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum Stress

(2016) W. Rozpedek et al.   CURRENT MOLECULAR MEDICINE

Effects of uterine and lactational exposure to di-(2-ethylhexyl) phthalate on spatial memory and NMDA receptor of hippocampus in mice

(2015) Yuhua Dai et al.   HORMONES AND BEHAVIOR

Gestational exposure to di(2-ethylhexyl) phthalate (DEHP) impairs pancreatic β-cell function in F1 rat offspring

(2015) P. Rajesh et al.   TOXICOLOGY LETTERS

Leaching of the plasticizer di(2-ethylhexyl)phthalate (DEHP) from plastic containers and the question of human exposure

(2014) Hanno C. Erythropel et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

H2O2 inhibits the growth of human pulmonary fibroblast cells by inducing cell death, GSH depletion and G1 phase arrest

(2013) WOO HYUN PARK   Molecular Medicine Reports

CHOP Potentially Co-Operates with FOXO3a in Neuronal Cells to Regulate PUMA and BIM Expression in Response to ER Stress

(2012) Arindam P. Ghosh et al.   PLoS One

The role of the IRE1 pathway in PBDE-47-induced toxicity in human neuroblastoma SH-SY5Y cells in vitro

(2012) Chunyang Jiang et al.   TOXICOLOGY LETTERS

Translational Pausing Ensures Membrane Targeting and Cytoplasmic Splicing of XBP1u mRNA

(2011) K. Yanagitani et al.   SCIENCE

Oxidative Stress, Redox Homeostasis and Cellular Stress Response in Ménière’s Disease: Role of Vitagenes

(2010) Vittorio Calabrese et al.   NEUROCHEMICAL RESEARCH

PCAF interacts with XBP-1S and mediates XBP-1S-dependent transcription

(2010) Q. J. Lew et al.   NUCLEIC ACIDS RESEARCH

Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement

(2009) Evanthia Diamanti-Kandarakis et al.   ENDOCRINE REVIEWS