Eucalyptol relieves the toxicity of diisobutyl phthalate in Ctenopharyngodon idellus kidney cells through Keap1/Nrf2/HO-1 pathway: Apoptosis-autophagy crosstalk and immunoregulation

Lycopene attenuates oxidative stress, inflammation, and apoptosis by modulating Nrf2/NF-κB balance in sulfamethoxazole-induced neurotoxicity in grass carp (Ctenopharyngodon Idella)

(2022) Yu Wang et al.   FISH & SHELLFISH IMMUNOLOGY

Realgar facilitates the Nrf2-Keap1-p62 positive feedback signaling axis via MAPKs and AKT to interfere with autophagy-induced apoptosis and oxidative stress in the hippocampus

(2022) Yuan Meng et al.   BIOMEDICINE & PHARMACOTHERAPY

Umbelliferone prevents isoproterenol-induced myocardial injury by upregulating Nrf2/HO-1 signaling, and attenuating oxidative stress, inflammation, and cell death in rats

(2022) Osama Y. Althunibat et al.   BIOMEDICINE & PHARMACOTHERAPY

Cineole alleviates the BPA-inhibited NETs formation by regulating the p38 pathway-mediated programmed cell death

(2022) Lu Chen et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Distribution and ecological risk assessment of phthalic acid esters in surface sediments of three rivers in Northern Vietnam

(2022) Thuy Minh Le et al.   ENVIRONMENTAL RESEARCH

β-Defensin: An adroit saviour in teleosts

(2022) Sweta Das et al.   FISH & SHELLFISH IMMUNOLOGY

Polystyrene nanoplastics induced cardiomyocyte apoptosis and myocardial inflammation in carp by promoting ROS production

(2022) Hao Wu et al.   FISH & SHELLFISH IMMUNOLOGY

Silencing of Nrf2 in Litopenaeus vannamei, decreased the antioxidant capacity, and increased apoptosis and autophagy

(2022) Yongxiong Huang et al.   FISH & SHELLFISH IMMUNOLOGY

Microplastics: A major source of phthalate esters in aquatic environments

(2022) Yaru Cao et al.   JOURNAL OF HAZARDOUS MATERIALS

Nobiletin Induces Ferroptosis in Human Skin Melanoma Cells Through the GSK3β-Mediated Keap1/Nrf2/HO-1 Signalling Pathway

(2022) Senling Feng et al.   Frontiers in Genetics

Eucalyptol relieves imidacloprid-induced autophagy through the miR-451/Cab39/AMPK axis in Ctenopharyngodon idellus kidney cells†

(2022) Xiaojing Li et al.   AQUATIC TOXICOLOGY

The endoplasmic reticulum-mitochondrial crosstalk is involved in the mitigation mechanism of eucalyptol on imidacloprid toxicity in Ctenopharyngodon idellus kidney cells

(2022) Xiaojing Li et al.   FISH & SHELLFISH IMMUNOLOGY

Protective effects of thymol on deltamethrin-induced toxicity of Channa argus in association with the NF-κB/Nrf2/p53 pathway

(2022) Min Li et al.   AQUACULTURE

Hepcidin-1 in olive flounder (Paralichthys olivaceus): Gene expression, antimicrobial and therapeutic effects of synthetic peptides against bacterial and viral infections

(2022) Yoonhang Lee et al.   AQUACULTURE

Associations between Children's asthma and allergic symptoms and phthalates in dust in metropolitan Tianjin, China

(2022) Changqi Zhu et al.   CHEMOSPHERE

Paraquat induces apoptosis, programmed necrosis, and immune dysfunction in CIK cells via the PTEN/PI3K/AKT axis

(2022) Xu Shi et al.   FISH & SHELLFISH IMMUNOLOGY

Hazards of phthalates (PAEs) exposure: A review of aquatic animal toxicology studies

(2021) Ying Zhang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Direct Keap1-kelch inhibitors as potential drug candidates for oxidative stress-orchestrated diseases: A review on In silico perspective

(2021) Ibrahim Damilare Boyenle et al.   PHARMACOLOGICAL RESEARCH

Transcriptomic responses predict the toxic effect of parental co-exposure to dibutyl phthalate and diisobutyl phthalate on the early development of zebrafish offspring

(2021) Hui Chen et al.   AQUATIC TOXICOLOGY

Sulforaphane inhibits blue light–induced inflammation and apoptosis by upregulating the SIRT1/PGC-1α/Nrf2 pathway and autophagy in retinal pigment epithelial cells

(2021) Po-Min Yang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Phthalic Acid Esters: Natural Sources and Biological Activities

(2021) Ling Huang et al.   Toxins

Activation of Nrf2/HO-1 signaling: An important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular endothelial cells from oxidative stress

(2021) Qing Zhang et al.   Journal of Advanced Research

Dietary Taraxacum mongolicum polysaccharide ameliorates the growth, immune response, and antioxidant status in association with NF-κB, Nrf2 and TOR in Jian carp (Cyprinus carpio var. Jian)

(2021) Zhe Yu et al.   AQUACULTURE

Emodin alleviates acute hypoxia-induced apoptosis in gibel carp (Carassius gibelio) by upregulating autophagy through modulation of the AMPK/mTOR pathway

(2021) Liyun Wu et al.   AQUACULTURE

Pig lung fibrosis is active in the subacute CdCl2 exposure model and exerts cumulative toxicity through the M1/M2 imbalance

(2021) Shi Xu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Exposure to imidacloprid induce oxidative stress, mitochondrial dysfunction, inflammation, apoptosis and mitophagy via NF-kappaB/JNK pathway in grass carp hepatocytes

(2021) Zhiruo Miao et al.   FISH & SHELLFISH IMMUNOLOGY

Chlorpyrifos triggers epithelioma papulosum cyprini cell pyroptosis via miR-124-3p/CAPN1 axis

(2021) Zhiying Miao et al.   JOURNAL OF HAZARDOUS MATERIALS

Occurrence, spatial distribution and ecological risk assessment of phthalate esters in water, soil and sediment from Yangtze River Delta, China

(2021) Qingqing Zhu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Occurrence of phthalic acid esters in marine organisms from Hangzhou Bay, China: Implications for human exposure

(2020) Hongmei Hu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Effects of dietary eucalyptol administration on antioxidant and inflammatory genes in common carp (Cyprinus carpio) exposed to ambient copper

(2020) Zohreh Fazelan et al.   AQUACULTURE

Sulforaphane suppresses obesity-related glomerulopathy-induced damage by enhancing autophagy via Nrf2

(2020) Yue Lu et al.   LIFE SCIENCES

Exercise protects against ethanol-induced damage in rat heart and liver through the inhibition of apoptosis and activation of Nrf2/Keap-1/HO-1 pathway

(2020) Rozita Fathi et al.   LIFE SCIENCES

DEHP-induce damage in grass carp hepatocytes and the remedy of Eucalyptol

(2020) Yuan Cui et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Inhibiting autophagy enhances sulforaphane-induced apoptosis via targeting NRF2 in esophageal squamous cell carcinoma

(2020) Zhaoming Lu et al.   Acta Pharmaceutica Sinica B

Effect of Chinese Medicine Xinmaitong on Blood Pressure in Spontaneously Hypertensive Rats

(2020) Bin Zhang et al.   Cardiology Research and Practice

H2S exposure-induced oxidative stress promotes LPS-mediated hepatocyte autophagy through the PI3K/AKT/TOR pathway

(2020) Jin-ming Guo et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Olea europaea leaf extract up-regulates Nrf2/ARE/HO-1 signaling and attenuates cyclophosphamide-induced oxidative stress, inflammation and apoptosis in rat kidney

(2019) Haifa A.S. ALHaithloul et al.   BIOMEDICINE & PHARMACOTHERAPY

Cell death: a review of the major forms of apoptosis, necrosis and autophagy

(2019) Mark S D’Arcy   CELL BIOLOGY INTERNATIONAL

Acute effects on human sperm exposed in vitro to cadmium chloride and diisobutyl phthalate

(2019) S Marchiani et al.   REPRODUCTION

Phthalate esters (PAEs) in atmospheric particles around a large shallow natural lake (Lake Chaohu, China)

(2019) Yong He et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Effects of dietary 1,8-cineole supplementation on physiological, immunological and antioxidant responses to crowding stress in rainbow trout ( Oncorhynchus mykiss )

(2018) Ali Taheri Mirghaed et al.   FISH & SHELLFISH IMMUNOLOGY

Dietary exposure to di-isobutyl phthalate increases urinary 5-methyl-2′-deoxycytidine level and affects reproductive function in adult male mice

(2017) Yitao Pan et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

5-Aminolevulinic acid with sodium ferrous citrate induces autophagy and protects cardiomyocytes from hypoxia-induced cellular injury through MAPK-Nrf-2-HO-1 signaling cascade

(2016) Mingyi Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Heme oxygenase-1 enhances autophagy in podocytes as a protective mechanism against high glucose-induced apoptosis

(2015) Chenglong Dong et al.   EXPERIMENTAL CELL RESEARCH

Self-consumption: the interplay of autophagy and apoptosis

(2014) Guillermo Mariño et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pulmonary Oxidative Stress, Inflammation and Cancer: Respirable Particulate Matter, Fibrous Dusts and Ozone as Major Causes of Lung Carcinogenesis through Reactive Oxygen Species Mechanisms

(2013) Athanasios Valavanidis et al.   International Journal of Environmental Research and Public Health

Antimicrobial Peptides for Therapeutic Applications: A Review

(2012) Min-Duk Seo et al.   MOLECULES

Cell death and production of reactive oxygen species by murine macrophages after short term exposure to phthalates

(2009) J. Naarala et al.   TOXICOLOGY LETTERS

Eucalyptus essential oil as a natural pesticide

(2008) Daizy R. Batish et al.   FOREST ECOLOGY AND MANAGEMENT