Sulforaphane inhibits blue light–induced inflammation and apoptosis by upregulating the SIRT1/PGC-1α/Nrf2 pathway and autophagy in retinal pigment epithelial cells

Mitochondria as Potential Targets and Initiators of the Blue Light Hazard to the Retina

(2019) Jin-Xin Tao et al.   Oxidative Medicine and Cellular Longevity

Intracellular sensing of viral genomes and viral evasion

(2019) Hyun-Cheol Lee et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Retinal pigment epithelial cells as a therapeutic tool and target against retinopathies

(2018) Barbara Pavan et al.   DRUG DISCOVERY TODAY

Removal of the blue component of light significantly decreases retinal damage after high intensity exposure

(2018) Javier Vicente-Tejedor et al.   PLoS One

PGC-1α Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis

(2018) Kai Kaarniranta et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro

(2018) Peng Lei et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration

(2018) Szabolcs Felszeghy et al.   Redox Biology

p62 links the autophagy pathway and the ubiqutin–proteasome system upon ubiquitinated protein degradation

(2016) Wei Jing Liu et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

SIRT1 exerts protective effects against paraquat-induced injury in mouse type II alveolar epithelial cells by deacetylating NRF2 in vitro

(2016) YING-WEI DING et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Lycopene inhibits ICAM-1 expression and NF-κB activation by Nrf2-regulated cell redox state in human retinal pigment epithelial cells

(2016) Po-Min Yang et al.   LIFE SCIENCES

Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD

(2014) Sayak K Mitter et al.   Autophagy

CO-releasing molecules and increased heme oxygenase-1 induce protein S-glutathionylation to modulate NF-κB activity in endothelial cells

(2014) Po-Yen Yeh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Carbon Monoxide Induces Heme Oxygenase-1 to Modulate STAT3 Activation in Endothelial Cells via S-Glutathionylation

(2014) Yan-Chang Yang et al.   PLoS One

Nrf2 signaling is impaired in the aging RPE given an oxidative insult

(2013) Mira M. Sachdeva et al.   EXPERIMENTAL EYE RESEARCH

Blue LED light exposure develops intracellular reactive oxygen species, lipid peroxidation, and subsequent cellular injuries in cultured bovine retinal pigment epithelial cells

(2013) T. Nakanishi-Ueda et al.   FREE RADICAL RESEARCH

Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process

(2013) Antero Salminen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Is sunlight exposure a risk factor for age-related macular degeneration? A systematic review and meta-analysis

(2012) Guo-Yuan Sui et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Monocyte Chemoattractant Protein 1, Intercellular Adhesion Molecule 1, and Vascular Cell Adhesion Molecule 1 in Exudative Age-Related Macular Degeneration

(2010) Jost B. Jonas   ARCHIVES OF OPHTHALMOLOGY

Age-related macular degeneration: genetic and clinical findings

(2010) Haris Kokotas et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

The Retinal Pigment Epithelium in Health and Disease

(2010) J. R. Sparrrow et al.   CURRENT MOLECULAR MEDICINE

Involvement of All-trans-retinal in Acute Light-induced Retinopathy of Mice

(2009) Akiko Maeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sunlight Exposure, Antioxidants, and Age-Related Macular Degeneration

(2008) Astrid E. Fletcher   ARCHIVES OF OPHTHALMOLOGY

Curcumin protects retinal cells from light-and oxidant stress-induced cell death

(2008) Md Nawajes A. Mandal et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cinnamaldehyde inhibits the tumor necrosis factor-α-induced expression of cell adhesion molecules in endothelial cells by suppressing NF-κB activation: Effects upon IκB and Nrf2

(2008) Being-Chyuan Liao et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY