CircFAT1 regulates retinal pigment epithelial cell pyroptosis and autophagy via mediating m6A reader protein YTHDF2 expression in diabetic retinopathy

Gypenoside XVII alleviates early diabetic retinopathy by regulating Müller cell apoptosis and autophagy in db/db mice

(2021) Yun Luo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Circular RNA hsa_circ_0072309 promotes tumorigenesis and invasion by regulating the miR-607/FTO axis in non-small cell lung carcinoma

(2021) Wei-Lie Mo et al.   Aging-US

Inhibition of autophagy‐dependent pyroptosis attenuates cerebral ischaemia/reperfusion injury

(2021) Hui Liu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway

(2021) Lujia Feng et al.   Autophagy

The Function and Therapeutic Potential of Circular RNA in Cardiovascular Diseases

(2021) Kai Wang et al.   CARDIOVASCULAR DRUGS AND THERAPY

Role of pyroptosis in diabetic retinopathy and its therapeutic implications

(2021) Abdullah Al Mamun et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The potential role of m6A RNA methylation in diabetic retinopathy

(2021) Nidhi Kumari et al.   EXPERIMENTAL EYE RESEARCH

Relative Contribution of Different Mitochondrial Oxidative Phosphorylation Components to the Retinal Pigment Epithelium Barrier Function: Implications for RPE-Related Retinal Diseases

(2021) Michael H. Guerra et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

KAT1 triggers YTHDF2-mediated ITGB1 mRNA instability to alleviate the progression of diabetic retinopathy

(2021) Ying Qi et al.   PHARMACOLOGICAL RESEARCH

Identification of MDM2, YTHDF2 and DDX21 as potential biomarkers and targets for treatment of type 2 diabetes

(2021) Junyi Zheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

GDF-11 Protects the Traumatically Injured Spinal Cord by Suppressing Pyroptosis and Necroptosis via TFE3-Mediated Autophagy Augmentation

(2021) Yu Xu et al.   Oxidative Medicine and Cellular Longevity

circACTR2: A Novel Mechanism Regulating High Glucose-Induced Fibrosis in Renal Tubular Cells via Pyroptosis

(2020) Si Wen et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

N6-methyladenine RNA modification (m6A): an emerging regulator of metabolic diseases.

(2020) Hui Zhong et al.   CURRENT DRUG TARGETS

Overexpression of METTL3 attenuates high-glucose induced RPE cell pyroptosis by regulating miR-25-3p/PTEN/Akt signaling cascade through DGCR8

(2020) Xu Zha et al.   Aging-US

Exosomes derived from mmu_circ_0000250-modified adipose-derived mesenchymal stem cells promote wound healing in diabetic mice by inducing miR-128-3p/SIRT1-mediated autophagy

(2020) Rongfeng Shi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Inhibition of hsa_circ_0002570 suppresses high-glucose–induced angiogenesis and inflammation in retinal microvascular endothelial cells through miR-1243/angiomotin axis

(2020) Guodan Liu et al.   CELL STRESS & CHAPERONES

Palbinone alleviates diabetic retinopathy in STZ-induced rats by inhibiting NLRP3 inflammatory activity

(2020) Qiang Shi et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Interaction between N6-methyladenosine (m6A) modification and noncoding RNAs in cancer

(2020) Yi Chen et al.   Molecular Cancer

Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells

(2020) Zhiwei Zhou et al.   SCIENCE

High Glucose Induces the Loss of Retinal Pericytes Partly via NLRP3-Caspase-1-GSDMD-Mediated Pyroptosis

(2020) Jinhua Gan et al.   Biomed Research International

PG545 alleviates diabetic retinopathy by promoting retinal Müller cell autophagy to inhibit the inflammatory response

(2020) Ying Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

FTO regulates ocular angiogenesis via m6A-YTHDF2-dependent mechanism

(2020) Kun Shan et al.   EXPERIMENTAL EYE RESEARCH

circRNA_0084043 contributes to the progression of diabetic retinopathy via sponging miR-140-3p and inducing TGFA gene expression in retinal pigment epithelial cells

(2020) Ying Li et al.   GENE

Inflammasome and Mitophagy Connection in Health and Disease

(2020) Jae-Min Yuk et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MD1 deletion exaggerates cardiomyocyte autophagy induced by heart failure with preserved ejection fraction through ROS/MAPK signalling pathway

(2020) Hong‐Jie Yang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Circ-ADAM9 targeting PTEN and ATG7 promotes autophagy and apoptosis of diabetic endothelial progenitor cells by sponging mir-20a-5p

(2020) Ding Tian et al.   Cell Death & Disease

Baicalein Attenuates Pyroptosis and Endoplasmic Reticulum Stress Following Spinal Cord Ischemia-Reperfusion Injury via Autophagy Enhancement

(2020) Chenyu Wu et al.   Frontiers in Pharmacology

Eicosanoids and Oxidative Stress in Diabetic Retinopathy

(2020) Mong-Heng Wang et al.   Antioxidants

Circular RNAs: Potential Star Molecules Involved in Diabetic Retinopathy

(2020) Miao He et al.   CURRENT EYE RESEARCH

Circular RNA COL1A2 promotes angiogenesis via regulating miR-29b/VEGF axis in diabetic retinopathy

(2020) Jing Zou et al.   LIFE SCIENCES

CircMEG3 inhibits telomerase activity by reducing Cbf5 in human liver cancer stem cells

(2020) Xiaoxue Jiang et al.   Molecular Therapy-Nucleic Acids

lncRNA H19 prevents endothelial–mesenchymal transition in diabetic retinopathy

(2019) Anu A. Thomas et al.   DIABETOLOGIA

Oxidative Stress and Microvascular Alterations in Diabetic Retinopathy: Future Therapies

(2019) María L. Rodríguez et al.   Oxidative Medicine and Cellular Longevity

Downregulation of circRNA DMNT3B contributes to diabetic retinal vascular dysfunction through targeting miR-20b-5p and BAMBI

(2019) Ke Zhu et al.   EBioMedicine

Use of smartphones for detecting diabetic retinopathy: a protocol for a scoping review of diagnostic test accuracy studies

(2019) Choon Han Tan et al.   BMJ Open

Targeting AMPK in Diabetes and Diabetic Complications: Energy homeostasis, Autophagy and Mitochondrial health

(2018) Y. V. Madhavi et al.   CURRENT MEDICINAL CHEMISTRY

Glucose is involved in the dynamic regulation of m6A in patients with type 2 diabetes

(2018) Ying Yang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Endogenous insulin signaling in the RPE contributes to the maintenance of rod photoreceptor function in diabetes

(2018) Matthew J. Tarchick et al.   EXPERIMENTAL EYE RESEARCH

Autophagy in Diabetic Retinopathy

(2016) Michelino Di Rosa et al.   Current Neuropharmacology

GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

(2016) Lorenzo Sborgi et al.   EMBO JOURNAL

Modulation of inflammation by autophagy: Consequences for human disease

(2015) Romana T. Netea-Maier et al.   Autophagy

Regulation of autophagy by transforming growth factor-β (TGF-β) signaling

(2010) Hiroshi I. Suzuki et al.   Autophagy