A systematic exploration of boceprevir-based main protease inhibitors as SARS-CoV-2 antivirals
Published 2022 View Full Article
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Title
A systematic exploration of boceprevir-based main protease inhibitors as SARS-CoV-2 antivirals
Authors
Keywords
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Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 240, Issue -, Pages 114596
Publisher
Elsevier BV
Online
2022-07-08
DOI
10.1016/j.ejmech.2022.114596
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Note: Only part of the references are listed.- Evaluation of SARS-CoV-2 Main Protease Inhibitors Using a Novel Cell-Based Assay
- (2022) Wenyue Cao et al. ACS Central Science
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- (2022) Yuying Ma et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Targeting the Main Protease of SARS‐CoV‐2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors
- (2021) Julian Breidenbach et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A drug repurposing screen identifies hepatitis C antivirals as inhibitors of the SARS-CoV2 main protease
- (2021) Jeremy D. Baker et al. PLoS One
- Bepridil is potent against SARS-CoV-2 in vitro
- (2021) Erol C. Vatansever et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SARS-CoV-2 Mpro inhibitors with antiviral activity in a transgenic mouse model
- (2021) Jingxin Qiao et al. SCIENCE
- Potent Noncovalent Inhibitors of the Main Protease of SARS-CoV-2 from Molecular Sculpting of the Drug Perampanel Guided by Free Energy Perturbation Calculations
- (2021) Chun-Hui Zhang et al. ACS Central Science
- Design, Synthesis, and Biological Evaluation of Peptidomimetic Aldehydes as Broad-Spectrum Inhibitors against Enterovirus and SARS-CoV-2
- (2021) Wenhao Dai et al. JOURNAL OF MEDICINAL CHEMISTRY
- X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease
- (2021) Sebastian Günther et al. SCIENCE
- A head-to-head comparison of the inhibitory activities of 15 peptidomimetic SARS-CoV-2 3CLpro inhibitors
- (2021) Subramanyam Vankadara et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- 3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents
- (2021) Sho Konno et al. JOURNAL OF MEDICINAL CHEMISTRY
- Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies
- (2021) Wayne Vuong et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of Di- and Trihaloacetamides as Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity
- (2021) Chunlong Ma et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- An oral SARS-CoV-2 M pro inhibitor clinical candidate for the treatment of COVID-19
- (2021) Dafydd R. Owen et al. SCIENCE
- Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332
- (2021) Yao Zhao et al. Protein & Cell
- Learning from the Past: Possible Urgent Prevention and Treatment Options for Severe Acute Respiratory Infections Caused by 2019‐nCoV
- (2020) Jared S. Morse et al. CHEMBIOCHEM
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
- (2020) David E. Gordon et al. NATURE
- Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors
- (2020) Zhenming Jin et al. NATURE
- Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur
- (2020) Zhenming Jin et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease
- (2020) Wenhao Dai et al. SCIENCE
- Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
- (2020) Linlin Zhang et al. SCIENCE
- Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease
- (2020) Chunlong Ma et al. CELL RESEARCH
- Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
- (2020) Laura Riva et al. NATURE
- Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs
- (2020) Zhe Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Malleability of the SARS-CoV-2 3CL Mpro active site cavity facilitates binding of clinical antivirals
- (2020) Daniel W. Kneller et al. STRUCTURE
- Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2
- (2020) Mohammad M. Ghahremanpour et al. ACS Medicinal Chemistry Letters
- Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease
- (2020) Lifeng Fu et al. Nature Communications
- Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease
- (2020) Alice Douangamath et al. Nature Communications
- Virology, transmission, and pathogenesis of SARS-CoV-2
- (2020) Muge Cevik et al. BMJ-British Medical Journal
- Furin Inhibitors Block SARS-CoV-2 Spike Protein Cleavage to Suppress Virus Production and Cytopathic Effects
- (2020) Ya-Wen Cheng et al. Cell Reports
- A Quick Route to Multiple Highly Potent SARS‐CoV‐2 Main Protease Inhibitors**
- (2020) Kai S. Yang et al. ChemMedChem
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