Malleability of the SARS-CoV-2 3CL Mpro active site cavity facilitates binding of clinical antivirals

Title
Malleability of the SARS-CoV-2 3CL Mpro active site cavity facilitates binding of clinical antivirals
Authors
Keywords
room temperature X-ray crystallography, SARS-CoV-2, 3CL main protease, 3CL M, protease inhibitor, hepatitis C clinical drugs, enzyme kinetics, drug design, repurposing clinical drugs
Journal
STRUCTURE
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2020-10-24
DOI
10.1016/j.str.2020.10.007

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