Design and synthesis of novel benzimidazole derivatives as potential Pseudomonas aeruginosa anti-biofilm agents inhibiting LasR: Evidence from comprehensive molecular dynamics simulation and in vitro investigation

Accurate determination of protein:ligand standard binding free energies from molecular dynamics simulations

(2022) Haohao Fu et al.   Nature Protocols

A phage-encoded anti-activator inhibits quorum sensing in Pseudomonas aeruginosa

(2021) Megha Shah et al.   MOLECULAR CELL

Benchmark of Popular Free Energy Approaches Revealing the Inhibitors Binding to SARS-CoV-2 Mpro

(2021) Son Tung Ngo et al.   Journal of Chemical Information and Modeling

AutoDock Vina 1.2.0: New Docking Methods, Expanded Force Field, and Python Bindings

(2021) Jerome Eberhardt et al.   Journal of Chemical Information and Modeling

Beyond Risk: Bacterial Biofilms and Their Regulating Approaches

(2020) Musa Hassan Muhammad et al.   Frontiers in Microbiology

Combining antibiotics with antivirulence compounds can have synergistic effects and reverse selection for antibiotic resistance in Pseudomonas aeruginosa

(2020) Chiara Rezzoagli et al.   PLOS BIOLOGY

An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor

(2019) Jon E. Paczkowski et al.   ACS Chemical Biology

Mosloflavone attenuates the quorum sensing controlled virulence phenotypes and biofilm formation in Pseudomonas aeruginosa PAO1: In vitro, in vivo and in silico approach

(2019) Sairengpuii Hnamte et al.   MICROBIAL PATHOGENESIS

Mechanism of agonism and antagonism of the Pseudomonas aeruginosa quorum sensing regulator QscR with non-native ligands

(2018) Christina L. Wysoczynski-Horita et al.   MOLECULAR MICROBIOLOGY

Quercetin is an effective inhibitor of quorum sensing, biofilm formation and virulence factors inPseudomonas aeruginosa

(2016) J. Ouyang et al.   JOURNAL OF APPLIED MICROBIOLOGY

Cellular Effects of Pyocyanin, a Secreted Virulence Factor of Pseudomonas aeruginosa

(2016) Susan Hall et al.   Toxins

Targeting quorum sensing by designing azoline derivatives to inhibit the N-hexanoyl homoserine lactone-receptor CviR: Synthesis as well as biological and theoretical evaluations

(2015) Alejandro Bucio-Cano et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Susceptibility to echinocandins of Candida spp. strains isolated in Italy assessed by European Committee for Antimicrobial Susceptibility Testing and Clinical Laboratory Standards Institute broth microdilution methods

(2015) Maria Teresa Montagna et al.   BMC MICROBIOLOGY

Antimicrobial resistance: a global multifaceted phenomenon

(2015) Francesca Prestinaci et al.   Pathogens and Global Health

Active Efflux Influences the Potency of Quorum Sensing Inhibitors inPseudomonas aeruginosa

(2014) Joseph D. Moore et al.   CHEMBIOCHEM

Identification of lactobacilli with inhibitory effect on biofilm formation by pathogenic bacteria on stainless steel surfaces

(2014) Fatma Ait Ouali et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Responses of Pseudomonas aeruginosa to antimicrobials

(2014) Yuji Morita et al.   Frontiers in Microbiology

Prevention of quorum-sensing-mediated biofilm development and virulence factors production in Vibrio spp. by curcumin

(2013) Issac Abraham Sybiya Vasantha Packiavathy et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Exploiting Quorum Sensing To Confuse Bacterial Pathogens

(2013) B. LaSarre et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Pseudomonas aeruginosa: new insights into pathogenesis and host defenses

(2013) Shaan L. Gellatly et al.   Pathogens and Disease

2-Aminobenzimidazole Derivatives Strongly Inhibit and DispersePseudomonas aeruginosaBiofilms

(2012) Reto Frei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nucleotide, c-di-GMP, c-di-AMP, cGMP, cAMP, (p)ppGpp signaling in bacteria and implications in pathogenesis

(2012) Dimpy Kalia et al.   CHEMICAL SOCIETY REVIEWS

Synthesis and biological activity of novel barbituric and thiobarbituric acid derivatives against non-alcoholic fatty liver disease

(2011) Liang Ma et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Prevalence of virulence genes among bulgarian nosocomial and cystic fibrosis isolates of Pseudomonas aeruginosa

(2010) Ivan Mitov et al.   BRAZILIAN JOURNAL OF MICROBIOLOGY

Quorum sensing-dependent virulence during Pseudomonas aeruginosa colonisation and pneumonia in mechanically ventilated patients

(2010) T. Kohler et al.   THORAX

Molecular Basis for the Recognition of Structurally Distinct Autoinducer Mimics by the Pseudomonas aeruginosa LasR Quorum-Sensing Signaling Receptor

(2009) Yaozhong Zou et al.   CHEMISTRY & BIOLOGY

Principles of assessing bacterial susceptibility to antibiotics using the agar diffusion method

(2008) B. Bonev et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY