Per- and Polyfluoroalkyl Substances (PFASs) Impair Lipid Metabolism in Rana nigromaculata: A Field Investigation and Laboratory Study

Quantifying Indirect Contribution from Precursors to Human Body Burden of Legacy PFASs Based on Paired Blood and One-Week Duplicate Diet

(2022) Xin Chen et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Tissue-Specific Uptake, Depuration Kinetics, and Suspected Metabolites of Three Emerging Per- and Polyfluoroalkyl Substances (PFASs) in Marine Medaka

(2022) Qi Wang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

(2022) Tingting Yan et al.   HEPATOLOGY

Natural PPARs agonists for the treatment of nonalcoholic fatty liver disease

(2022) Jiashu Pan et al.   BIOMEDICINE & PHARMACOTHERAPY

Legacy and Emerging Poly- and Perfluoroalkyl Substances in Finless Porpoises from East China Sea: Temporal Trends and Tissue-Specific Accumulation

(2021) Bo Zhang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

YAP‐TEAD mediates peroxisome proliferator‐activated receptor α‐induced hepatomegaly and liver regeneration in mice

(2021) Shicheng Fan et al.   HEPATOLOGY

Perfluorooctanoic acid induces liver and serum dyslipidemia in humanized PPARα mice fed an American diet

(2021) J.J. Schlezinger et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Fluorinated Compounds in North American Cosmetics

(2021) Heather D. Whitehead et al.   Environmental Science & Technology Letters

Binding and activity of bisphenol analogues to human peroxisome proliferator-activated receptor β/δ

(2021) Chuan-Hai Li et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Arsenic and weight loss: At a crossroad between lipogenesis and lipolysis

(2021) Somayeh Handali et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Uncovering pathophysiological changes in frontotemporal dementia using serum lipids

(2020) Katherine Phan et al.   Scientific Reports

Probiotic modulation of lipid metabolism disorders caused by perfluorobutanesulfonate pollution in zebrafish

(2020) Lianguo Chen et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance

(2020) Kay H. M. Roumans et al.   Nature Communications

Receptor-Bound Perfluoroalkyl Carboxylic Acids Dictate Their Activity on Human and Mouse Peroxisome Proliferator-Activated Receptor γ

(2020) Chuan-Hai Li et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Disturbances in Microbial and Metabolic Communication across the Gut–Liver Axis Induced by a Dioxin-like Pollutant: An Integrated Metagenomics and Metabolomics Analysis

(2020) Chenyan Hu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Health Status of Elderly People Living Near E-Waste Recycling Sites: Association of E-Waste Dismantling Activities with Legacy Perfluoroalkyl Substances (PFASs)

(2019) Tao Zhang et al.   Environmental Science & Technology Letters

It takes a village: channeling fatty acid metabolism and triacylglycerol formation via protein interactomes

(2019) Rosalind A. Coleman   JOURNAL OF LIPID RESEARCH

Tributyltin Affects Retinoid X Receptor-Mediated Lipid Metabolism in the Marine Rotifer Brachionus koreanus

(2019) Min-Chul Lee et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Ecological toxicity reduction of dinotefuran to honeybee: New perspective from an enantiomeric level

(2019) Zenglong Chen et al.   ENVIRONMENT INTERNATIONAL

Maternal Polystyrene Microplastic Exposure during Gestation and Lactation Altered Metabolic Homeostasis in the Dams and Their F1 and F2 Offspring

(2019) Ting Luo et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Inhibition of Mitochondrial Fatty Acid Oxidation Contributes to Development of Nonalcoholic Fatty Liver Disease Induced by Environmental Cadmium Exposure

(2019) Xiwei He et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate Affects Lipid Metabolism in Zebrafish Larvae via DNA Methylation Modification

(2019) Wei Guo et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Effects of environmental stressors on lipid metabolism in aquatic invertebrates

(2018) Min-Chul Lee et al.   AQUATIC TOXICOLOGY

Macrophages and lipid metabolism

(2018) Anneleen Remmerie et al.   CELLULAR IMMUNOLOGY

Effects of MCLR exposure on sex hormone synthesis and reproduction-related genes expression of testis in male Rana nigromaculata

(2018) Xiuying Jia et al.   ENVIRONMENTAL POLLUTION

Chlorinated Polyfluorinated Ether Sulfonates Exhibit Higher Activity toward Peroxisome Proliferator-Activated Receptors Signaling Pathways than Perfluorooctanesulfonate

(2018) Chuan-Hai Li et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Hepatotoxic Effects of Hexafluoropropylene Oxide Trimer Acid (HFPO-TA), A Novel Perfluorooctanoic Acid (PFOA) Alternative, on Mice

(2018) Nan Sheng et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Worldwide Distribution of Novel Perfluoroether Carboxylic and Sulfonic Acids in Surface Water

(2018) Yitao Pan et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Occurrence and Tissue Distribution of Novel Perfluoroether Carboxylic and Sulfonic Acids and Legacy Per/Polyfluoroalkyl Substances in Black-Spotted Frog (Pelophylax nigromaculatus)

(2018) Qianqian Cui et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Recent Asian origin of chytrid fungi causing global amphibian declines

(2018) Simon J. O’Hanlon et al.   SCIENCE

Liver X Receptor Inverse Agonist SR9243 Suppresses Nonalcoholic Steatohepatitis Intrahepatic Inflammation and Fibrosis

(2018) Peng Huang et al.   Biomed Research International

Differences in reproductive toxicity of TBBPA and TCBPA exposure in male Rana nigromaculata

(2018) Hangjun Zhang et al.   ENVIRONMENTAL POLLUTION

Subchronic Hepatotoxicity Effects of 6:2 Chlorinated Polyfluorinated Ether Sulfonate (6:2 Cl-PFESA), a Novel Perfluorooctane Sulfonate (PFOS) Alternative, on Adult Male Mice

(2018) Hongxia Zhang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

SREBP-1 and LXRα pathways mediated Cu-induced hepatic lipid metabolism in zebrafish Danio rerio

(2018) Ya-Xiong Pan et al.   CHEMOSPHERE

Lipid accumulation responses in the liver of Rana nigromaculata induced by perfluorooctanoic acid (PFOA)

(2018) Hangjun Zhang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Occurrence and seasonal variations of per- and polyfluoroalkyl substances (PFASs) including fluorinated alternatives in rivers, drain outlets and the receiving Bohai Sea of China

(2017) Hong Chen et al.   ENVIRONMENTAL POLLUTION

First Report on the Occurrence and Bioaccumulation of Hexafluoropropylene Oxide Trimer Acid: An Emerging Concern

(2017) Yitao Pan et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Atmospheric chlorinated polyfluorinated ether sulfonate and ionic perfluoroalkyl acids in 2006 to 2014 in Dalian, China

(2017) Wei Liu et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

The impact of exposure to environmental contaminant on hepatocellular lipid metabolism

(2017) Zongguang Hui et al.   GENE

Lipid droplets and liver disease: from basic biology to clinical implications

(2017) Nina L. Gluchowski et al.   Nature Reviews Gastroenterology & Hepatology

Perfluoroalkyl acids-induced liver steatosis: Effects on genes controlling lipid homeostasis

(2017) Kaberi P. Das et al.   TOXICOLOGY

Chronic perfluorooctane sulfonate (PFOS) exposure induces hepatic steatosis in zebrafish

(2016) Jiangfei Cheng et al.   AQUATIC TOXICOLOGY

Novel Chlorinated Polyfluorinated Ether Sulfonates and Legacy Per-/Polyfluoroalkyl Substances: Placental Transfer and Relationship with Serum Albumin and Glomerular Filtration Rate

(2016) Yitao Pan et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Metabolomics Reveals that Aryl Hydrocarbon Receptor Activation by Environmental Chemicals Induces Systemic Metabolic Dysfunction in Mice

(2015) Limin Zhang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Identification of Novel Polyfluorinated Ether Sulfonates as PFOS Alternatives in Municipal Sewage Sludge in China

(2015) Ting Ruan et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Perfluoroalkyl and polyfluoroalkyl substances in consumer products

(2015) Matthias Kotthoff et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Environmental pollutants directly affect the liver X receptor alpha activity: Kinetic and thermodynamic characterization of binding

(2015) Matteo Mozzicafreddo et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Pesticide concentrations in frog tissue and wetland habitats in a landscape dominated by agriculture

(2015) Kelly L. Smalling et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Obesogenic effects of endocrine disruptors, what do we know from animal and human studies?

(2014) Marijke de Cock et al.   ENVIRONMENT INTERNATIONAL

Effect of Body Condition on Tissue Distribution of Perfluoroalkyl Substances (PFASs) in Arctic Fox (Vulpes lagopus)

(2014) Camilla Bakken Aas et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

PFOS induced lipid metabolism disturbances in BALB/c mice through inhibition of low density lipoproteins excretion

(2014) Ling Wang et al.   Scientific Reports

Effects of perfluorooctanesulfonate and perfluorobutanesulfonate on the growth and sexual development of Xenopus laevis

(2013) Qin-Qin Lou et al.   ECOTOXICOLOGY

First Report of a Chinese PFOS Alternative Overlooked for 30 Years: Its Toxicity, Persistence, and Presence in the Environment

(2013) Siwen Wang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Structure-Based Investigation on the Interaction of Perfluorinated Compounds with Human Liver Fatty Acid Binding Protein

(2013) Lianying Zhang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Activation of Liver X receptors in the heart leads to accumulation of intracellular lipids and attenuation of ischemia–reperfusion injury

(2012) Peng Lei et al.   BASIC RESEARCH IN CARDIOLOGY

Perfluoroalkyl substances in human milk: A first survey in Italy

(2012) Andrea Barbarossa et al.   ENVIRONMENT INTERNATIONAL

Serum Perfluorooctanoate (PFOA) and Perfluorooctane Sulfonate (PFOS) Concentrations and Liver Function Biomarkers in a Population with Elevated PFOA Exposure

(2012) Valentina Gallo et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

A New Class of Selective and Potent 7-Dehydrocholesterol Reductase Inhibitors

(2012) Aline Horling et al.   JOURNAL OF MEDICINAL CHEMISTRY

Hepatocellular hypertrophy and cell proliferation in Sprague–Dawley rats from dietary exposure to potassium perfluorooctanesulfonate results from increased expression of xenosensor nuclear receptors PPARα and CAR/PXR

(2012) Clifford R. Elcombe et al.   TOXICOLOGY

The Complex and Important Cellular and Metabolic Functions of Saturated Fatty Acids

(2010) Philippe Legrand et al.   LIPIDS

Structural Insight into PPARγ Activation Through Covalent Modification with Endogenous Fatty Acids

(2008) Tsuyoshi Waku et al.   JOURNAL OF MOLECULAR BIOLOGY