It takes a village: channeling fatty acid metabolism and triacylglycerol formation via protein interactomes

The metabolic capacity of lipid droplet localized acyl-CoA synthetase 3 is not sufficient to support local triglyceride synthesis independent of the endoplasmic reticulum in A431 cells

(2018) Margarete Poppelreuther et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice

(2018) Albert G. Linden et al.   JOURNAL OF LIPID RESEARCH

The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation

(2018) Lee J. Sweetlove et al.   Nature Communications

Long-chain acyl-CoA synthetase 1 interacts with key proteins that activate and direct fatty acids into niche hepatic pathways

(2018) Pamela A. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A New View into the Regulation of Purine Metabolism: The Purinosome

(2017) Anthony M. Pedley et al.   TRENDS IN BIOCHEMICAL SCIENCES

Loss of long-chain acyl-CoA synthetase isoform 1 impairs cardiac autophagy and mitochondrial structure through mechanistic target of rapamycin complex 1 activation

(2015) Trisha J. Grevengoed et al.   FASEB JOURNAL

Glycerol-3-phosphate Acyltransferase Isoform-4 (GPAT4) Limits Oxidation of Exogenous Fatty Acids in Brown Adipocytes

(2015) Daniel E. Cooper et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physiological Consequences of Compartmentalized Acyl-CoA Metabolism

(2015) Daniel E. Cooper et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-induced insulin resistance by the enhanced association of mTOR and rictor

(2014) Chongben Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Compartmentalized Acyl-CoA Metabolism in Skeletal Muscle Regulates Systemic Glucose Homeostasis

(2014) Lei O. Li et al.   DIABETES

Decoding insulin resistance and metabolic syndrome for promising therapeutic intervention

(2014) Shaodong Guo   JOURNAL OF ENDOCRINOLOGY

Increased De Novo Lipogenesis Is a Distinct Characteristic of Individuals With Nonalcoholic Fatty Liver Disease

(2013) Jennifer E. Lambert et al.   GASTROENTEROLOGY

Glycerol-3-phosphate Acyltransferase (GPAT)-1, but Not GPAT4, Incorporates Newly Synthesized Fatty Acids into Triacylglycerol and Diminishes Fatty Acid Oxidation

(2013) Angela A. Wendel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycogen and its metabolism: some new developments and old themes

(2012) Peter J. Roach et al.   BIOCHEMICAL JOURNAL

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells

(2012) Kyle J. Roux et al.   JOURNAL OF CELL BIOLOGY

Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling

(2012) C. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian Triacylglycerol Metabolism: Synthesis, Lipolysis, and Signaling

(2011) Rosalind A. Coleman et al.   CHEMICAL REVIEWS

Mitochondrial Carnitine Palmitoyltransferase 1a (CPT1a) Is Part of an Outer Membrane Fatty Acid Transfer Complex

(2011) Kwangwon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mouse Cardiac Acyl Coenzyme A Synthetase 1 Deficiency Impairs Fatty Acid Oxidation and Induces Cardiac Hypertrophy

(2011) J. M. Ellis et al.   MOLECULAR AND CELLULAR BIOLOGY

Adipose Acyl-CoA Synthetase-1 Directs Fatty Acids toward β-Oxidation and Is Required for Cold Thermogenesis

(2010) Jessica M. Ellis et al.   Cell Metabolism

Glycerol-3-Phosphate Acyltransferase 1 Deficiency in ob/ob Mice Diminishes Hepatic Steatosis but Does Not Protect Against Insulin Resistance or Obesity

(2010) A. A. Wendel et al.   DIABETES

Liver-specific Loss of Long Chain Acyl-CoA Synthetase-1 Decreases Triacylglycerol Synthesis and β-Oxidation and Alters Phospholipid Fatty Acid Composition

(2009) Lei O. Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SREBPs: physiology and pathophysiology of the SREBP family

(2008) Hitoshi Shimano   FEBS Journal

AGPAT6 Is a Novel Microsomal Glycerol-3-phosphate Acyltransferase

(2008) Yan Qun Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a novelsn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient inAgpat6−/−mice

(2008) Cynthia A. Nagle et al.   JOURNAL OF LIPID RESEARCH