Metabolomics Reveal Nanoplastic-Induced Mitochondrial Damage in Human Liver and Lung Cells

Bioeffects of Inhaled Nanoplastics on Neurons and Alteration of Animal Behaviors through Deposition in the Brain

(2022) Xiaoyan Liu et al.   NANO LETTERS

Toxic effects of nanoplastics with different sizes and surface charges on epithelial-to-mesenchymal transition in A549 cells and the potential toxicological mechanism

(2022) Gulinare Halimu et al.   JOURNAL OF HAZARDOUS MATERIALS

Absorption, distribution, metabolism, excretion and toxicity of microplastics in the human body and health implications

(2022) Pengfei Wu et al.   JOURNAL OF HAZARDOUS MATERIALS

Nanoplastics impact on marine biota: A review

(2021) Joanna M. Gonçalves et al.   ENVIRONMENTAL POLLUTION

Continuous Dermal Exposure to Triclocarban Perturbs the Homeostasis of Liver–Gut Axis in Mice: Insights from Metabolic Interactions and Microbiome Shifts

(2021) Hongna Zhang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Microplastics and human health

(2021) A. Dick Vethaak et al.   SCIENCE

The Kidney-Related Effects of Polystyrene Microplastics on Human Kidney Proximal Tubular Epithelial Cells HK-2 and Male C57BL/6 Mice

(2021) Yung-Li Wang et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Tissue distribution of polystyrene nanoplastics in mice and their entry, transport, and cytotoxicity to GES-1 cells

(2021) Yunfei Ding et al.   ENVIRONMENTAL POLLUTION

AOP Report: Uncoupling of Oxidative Phosphorylation Leading to Growth Inhibition via Decreased Cell Proliferation

(2021) You Song et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Systematic toxicity evaluation of polystyrene nanoplastics on mice and molecular mechanism investigation about their internalization into Caco-2 cells

(2021) Dihui Xu et al.   JOURNAL OF HAZARDOUS MATERIALS

MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights

(2021) Zhiqiang Pang et al.   NUCLEIC ACIDS RESEARCH

Maternal exposure to polystyrene nanoplastics causes brain abnormalities in progeny

(2021) Bohyeon Jeong et al.   JOURNAL OF HAZARDOUS MATERIALS

A Review of Microplastics in Table salt, Drinking Water, and Air: Direct Human Exposure

(2020) Qun Zhang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Mitochondrial TCA cycle metabolites control physiology and disease

(2020) Inmaculada Martínez-Reyes et al.   Nature Communications

Toxicity of Microplastics and Nanoplastics in Mammalian Systems

(2020) Cheryl Qian Ying Yong et al.   International Journal of Environmental Research and Public Health

Large-scale Targeted Metabolomics Method for Metabolite Profiling of Human Samples

(2020) Guodong Cao et al.   ANALYTICA CHIMICA ACTA

Photodegradation Elevated the Toxicity of Polystyrene Microplastics to Grouper (Epinephelus moara) through Disrupting Hepatic Lipid Homeostasis

(2020) Xiao Wang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Mitochondria and T2D: Role of Autophagy, ER Stress, and Inflammasome

(2020) Milagros Rocha et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

In situ surface-enhanced Raman spectroscopy for detecting microplastics and nanoplastics in aquatic environments

(2020) Lulu Lv et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Polystyrene nanoplastics cause growth inhibition, morphological damage and physiological disturbance in the marine microalga Platymonas helgolandica

(2020) Shuyu Wang et al.   MARINE POLLUTION BULLETIN

Ion mobility collision cross-section atlas for known and unknown metabolite annotation in untargeted metabolomics

(2020) Zhiwei Zhou et al.   Nature Communications

Microplastic digestion generates fragmented nanoplastics in soils and damages earthworm spermatogenesis and coelomocyte viability

(2020) Jin Il Kwak et al.   JOURNAL OF HAZARDOUS MATERIALS

Recent advances in toxicological research of nanoplastics in the environment: A review

(2019) Maocai Shen et al.   ENVIRONMENTAL POLLUTION

Integration of Metabolomics and Lipidomics Reveals Metabolic Mechanisms of Triclosan-Induced Toxicity in Human Hepatocytes

(2019) Hongna Zhang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Exploring the protective effects of Danqi Tongmai tablet on acute myocardial ischemia rats by comprehensive metabolomics profiling

(2019) Zhenwei Li et al.   PHYTOMEDICINE

Nanoplastics Decrease the Toxicity of a Complex PAH Mixture but Impair Mitochondrial Energy Production in Developing Zebrafish

(2019) Rafael Trevisan et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Targeted metabolomics reveals differential biological effects of nanoplastics and nanoZnO in human lung cells

(2019) Swee Ling Lim et al.   Nanotoxicology

Energy metabolism controls phenotypes by protein efficiency and allocation

(2019) Yu Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoplastics: From tissue accumulation to cell translocation into Mytilus galloprovincialis hemocytes. resilience of immune cells exposed to nanoplastics and nanoplastics plus Vibrio splendidus combination

(2019) M. Sendra et al.   JOURNAL OF HAZARDOUS MATERIALS

Review on plastic wastes in marine environment – Biodegradation and biotechnological solutions

(2019) Ganesh Kumar A. et al.   MARINE POLLUTION BULLETIN

Potential health impact of environmental micro‐ and nanoplastics pollution

(2019) Xiaoru Chang et al.   JOURNAL OF APPLIED TOXICOLOGY

Internalization and toxicity: A preliminary study of effects of nanoplastic particles on human lung epithelial cell

(2019) Mingkai Xu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Turning microplastics into nanoplastics through digestive fragmentation by Antarctic krill

(2018) Amanda L. Dawson et al.   Nature Communications

Mass spectrometry-based metabolomics reveals the mechanism of ambient fine particulate matter and its components on energy metabolic reprogramming in BEAS-2B cells

(2018) Yuanyuan Song et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Cytotoxic effects of commonly used nanomaterials and microplastics on cerebral and epithelial human cells

(2017) Gabriella F. Schirinzi et al.   ENVIRONMENTAL RESEARCH

The emerging role and targetability of the TCA cycle in cancer metabolism

(2017) Nicole M. Anderson et al.   Protein & Cell

Are There Nanoplastics in Your Personal Care Products?

(2017) Laura M. Hernandez et al.   Environmental Science & Technology Letters

Polystyrene nanoparticles internalization in human gastric adenocarcinoma cells

(2016) Maurizio Forte et al.   TOXICOLOGY IN VITRO

The impact of debris on marine life

(2015) S.C. Gall et al.   MARINE POLLUTION BULLETIN

Differential bioreactivity of neutral, cationic and anionic polystyrene nanoparticles with cells from the human alveolar compartment: robust response of alveolar type 1 epithelial cells

(2015) Pakatip Ruenraroengsak et al.   Particle and Fibre Toxicology

Fumarate induces redox-dependent senescence by modifying glutathione metabolism

(2015) Liang Zheng et al.   Nature Communications

Molecular mechanisms of the microsomal mixed function oxidases and biological and pathological implications

(2015) Arthur I. Cederbaum   Redox Biology

The endoplasmic reticulum–mitochondria connection: One touch, multiple functions

(2013) Saverio Marchi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging

(2013) Ana P. Gomes et al.   CELL

The Proto-oncometabolite Fumarate Binds Glutathione to Amplify ROS-Dependent Signaling

(2013) Lucas B. Sullivan et al.   MOLECULAR CELL

Synthetic polymers in the marine environment: A rapidly increasing, long-term threat

(2008) Charles James Moore   ENVIRONMENTAL RESEARCH

Systems biology: Metabonomics

(2008) Jeremy K. Nicholson et al.   NATURE