Differential bioreactivity of neutral, cationic and anionic polystyrene nanoparticles with cells from the human alveolar compartment: robust response of alveolar type 1 epithelial cells

Complementary analysis of the hard and soft protein corona: sample preparation critically effects corona composition

(2015) S. Winzen et al.   Nanoscale

Critical Determinants of Uptake and Translocation of Nanoparticles by the Human Pulmonary Alveolar Epithelium

(2014) Andrew J. Thorley et al.   ACS Nano

Endosomal Escape: A Bottleneck in Intracellular Delivery

(2014) Harshad K. Shete et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Imaging Single Nanoparticle Interactions with Human Lung Cells Using Fast Ion Conductance Microscopy

(2014) Pavel Novak et al.   NANO LETTERS

Mimicking exposures to acute and lifetime concentrations of inhaled silver nanoparticles by two different in vitro approaches

(2014) Fabian Herzog et al.   Beilstein Journal of Nanotechnology

Low Dose of Amino-Modified Nanoparticles Induces Cell Cycle Arrest

(2013) Jong Ah Kim et al.   ACS Nano

Cell Membranes Open “Doors” for Cationic Nanoparticles/Biomolecules: Insights into Uptake Kinetics

(2013) Jiaqi Lin et al.   ACS Nano

Nano-sized and micro-sized polystyrene particles affect phagocyte function

(2013) B. Prietl et al.   CELL BIOLOGY AND TOXICOLOGY

Type 2 alveolar cells are stem cells in adult lung

(2013) Christina E. Barkauskas et al.   JOURNAL OF CLINICAL INVESTIGATION

New perspectives in nanomedicine

(2013) Andrew J. Thorley et al.   PHARMACOLOGY & THERAPEUTICS

Comprehensive Analysis of the Effects of CdSe Quantum Dot Size, Surface Charge, and Functionalization on Primary Human Lung Cells

(2012) Amber Nagy et al.   ACS Nano

Lipid-based carriers: manufacturing and applications for pulmonary route

(2012) Chiraz Jaafar-Maalej et al.   Expert Opinion on Drug Delivery

PEGylated Polyplex With Optimized PEG Shielding Enhances Gene Introduction in Lungs by Minimizing Inflammatory Responses

(2012) Satoshi Uchida et al.   MOLECULAR THERAPY

Functional interaction between charged nanoparticles and cardiac tissue: a new paradigm for cardiac arrhythmia?

(2012) Michele Miragoli et al.   Nanomedicine

Screening of different metal oxide nanoparticles reveals selective toxicity and inflammatory potential of silica nanoparticles in lung epithelial cells and macrophages

(2012) A. Panas et al.   Nanotoxicology

Proof of concept for next-generation nanoparticle drugs in humans

(2012) Cormac Sheridan   NATURE BIOTECHNOLOGY

Action of polystyrene nanoparticles of different sizes on lysosomal function and integrity

(2012) Eleonore Fröhlich et al.   Particle and Fibre Toxicology

Effect of Carbon Coating on the Physico-chemical Properties and Toxicity of Copper and Nickel Nanoparticles

(2012) Shalini Minocha et al.   Small

Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung

(2011) G McLachlan et al.   GENE THERAPY

Versatile cationic lipids for siRNA delivery

(2011) Jeff Sparks et al.   JOURNAL OF CONTROLLED RELEASE

Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA

(2011) Ditte Krohn Jensen et al.   JOURNAL OF CONTROLLED RELEASE

A Simulation Study on Nanoscale Holes Generated by Gold Nanoparticles on Negative Lipid Bilayers

(2011) Jia-Qi Lin et al.   LANGMUIR

Differential modulation of apoptotic gene expression by N-acetyl-l-cysteine in Leydig cells stimulated persistently with hCG in vivo

(2011) Archana Aggarwal et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Influence of Cationic Lipid Composition on Gene Silencing Properties of Lipid Nanoparticle Formulations of siRNA in Antigen-Presenting Cells

(2011) Genc Basha et al.   MOLECULAR THERAPY

Delivery of siRNA to the Mouse Lung via a Functionalized Lipopolyamine

(2011) Kevin J Polach et al.   MOLECULAR THERAPY

Respiratory epithelial cytotoxicity and membrane damage (holes) caused by amine-modified nanoparticles

(2011) Pakatip Ruenraroengsak et al.   Nanotoxicology

Innate Immune Responses to Bacterial Ligands in the Peripheral Human Lung – Role of Alveolar Epithelial TLR Expression and Signalling

(2011) Andrew J. Thorley et al.   PLoS One

Cellular Uptake, Cytotoxicity, and Innate Immune Response of Silica−Titania Hollow Nanoparticles Based on Size and Surface Functionality

(2010) Wan-Kyu Oh et al.   ACS Nano

Formation, characterization, and fate of inhaled drug nanoparticles

(2010) Jian Zhang et al.   ADVANCED DRUG DELIVERY REVIEWS

Nanoparticles: molecular targets and cell signalling

(2010) Francelyne Marano et al.   ARCHIVES OF TOXICOLOGY

Biocompatibility of polymer grafted core/shell iron/carbon nanoparticles

(2010) Qingxin Mu et al.   BIOMATERIALS

Micro- and nanocarrier-mediated lung targeting

(2010) Balak D Kurmi et al.   Expert Opinion on Drug Delivery

Endosomal escape pathways for delivery of biologicals

(2010) Amir K. Varkouhi et al.   JOURNAL OF CONTROLLED RELEASE

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells

(2010) Sourav Bhattacharjee et al.   Particle and Fibre Toxicology

Mechanisms of Alveolar Epithelial Translocation of a Defined Population of Nanoparticles

(2009) Nazanin R. Yacobi et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The role of nanoparticle concentration-dependent induction of cellular stress in the internalization of non-toxic cationic magnetoliposomes

(2009) Stefaan J.H. Soenen et al.   BIOMATERIALS

Antioxidant neuroprotection against ethanol-induced apoptosis in HN2-5 cells

(2009) Dhara S. Sheth et al.   BRAIN RESEARCH

Cationic surface modification of PLG nanoparticles offers sustained gene delivery to pulmonary epithelial cells

(2009) Abdulgader Baoum et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Cationic Nanoparticles Induce Nanoscale Disruption in Living Cell Plasma Membranes

(2009) Jiumei Chen et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

Immortalization of Human Alveolar Epithelial Cells to Investigate Nanoparticle Uptake

(2008) Sarah J. Kemp et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Biodegradable polymeric nanocarriers for pulmonary drug delivery

(2008) Erik Rytting et al.   Expert Opinion on Drug Delivery

The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles

(2008) Ning Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Polystyrene nanoparticle trafficking across alveolar epithelium

(2008) Nazanin R. Yacobi et al.   Nanomedicine-Nanotechnology Biology and Medicine

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

(2008) M. Lundqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA