Disrupting metformin adaptation of liver cancer cells by targeting the TOMM34 / ATP5B axis
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Title
Disrupting metformin adaptation of liver cancer cells by targeting the
TOMM34
/
ATP5B
axis
Authors
Keywords
-
Journal
EMBO Molecular Medicine
Volume -, Issue -, Pages -
Publisher
EMBO
Online
2022-11-02
DOI
10.15252/emmm.202216082
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Note: Only part of the references are listed.- Inhibition of NPC1L1 disrupts adaptive responses of drug‐tolerant persister cells to chemotherapy
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- (2021) Hai-Ning Chen et al. GUT
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- (2021) Alexis A. Jourdain et al. MOLECULAR CELL
- A Biochemical and Structural Understanding of TOM Complex Interactions and Implications for Human Health and Disease
- (2021) Ashley S. Pitt et al. Cells
- Innate immune response orchestrates phosphoribosyl pyrophosphate synthetases to support DNA repair
- (2021) Rui Liu et al. Cell Metabolism
- Metformin in Combination With Chemoradiotherapy in Locally Advanced Non–Small Cell Lung Cancer
- (2021) Theodoros Tsakiridis et al. JAMA Oncology
- The Multifaceted ATPase Inhibitory Factor 1 (IF1) in Energy Metabolism Reprogramming and Mitochondrial Dysfunction: A New Player in Age-Associated Disorders?
- (2021) Emilia Gore et al. ANTIOXIDANTS & REDOX SIGNALING
- Thyroid hormone inhibits hepatocellular carcinoma progression via induction of differentiation and metabolic reprogramming
- (2020) Marta Anna Kowalik et al. JOURNAL OF HEPATOLOGY
- BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis
- (2020) Qiang Chen et al. Advanced Science
- Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1
- (2020) Stéphanie Herkenne et al. Cell Metabolism
- AMPK activation by metformin promotes survival of dormant ER+ breast cancer cells
- (2020) Riley A Hampsch et al. CLINICAL CANCER RESEARCH
- Defining the Substrate Spectrum of the TIM22 Complex Identifies Pyruvate Carrier Subunits as Unconventional Cargos
- (2020) Ridhima Gomkale et al. CURRENT BIOLOGY
- Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis
- (2020) Zhen Cai et al. MOLECULAR CELL
- Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma
- (2019) Yufeng Shi et al. NATURE
- Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma
- (2019) Jingwen Jiang et al. Autophagy
- Metformin in breast cancer: preclinical and clinical evidence
- (2019) Anindita De et al. CURRENT PROBLEMS IN CANCER
- Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepatocellular carcinoma
- (2019) Ram C. Shankaraiah et al. ONCOGENE
- Acquired resistance to HER2-targeted therapies creates vulnerability to ATP synthase inhibition
- (2019) Molly Gale et al. CANCER RESEARCH
- Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK
- (2019) Yu Wang et al. Cell Reports
- Mitochondrial protein import regulates cytosolic protein homeostasis and neuronal integrity
- (2018) Wei Liu et al. Autophagy
- Oxidative Phosphorylation as an Emerging Target in Cancer Therapy
- (2018) Thomas M. Ashton et al. CLINICAL CANCER RESEARCH
- Mitochondria and the dynamic control of stem cell homeostasis
- (2018) Pawel Lisowski et al. EMBO REPORTS
- Circular RNA cSMARCA5 inhibits growth and metastasis in hepatocellular carcinoma
- (2018) Jian Yu et al. JOURNAL OF HEPATOLOGY
- The Effects of Metformin and Weight Loss on Biomarkers Associated With Breast Cancer Outcomes
- (2018) Ruth E Patterson et al. JNCI-Journal of the National Cancer Institute
- Mitochondrial dynamics in adaptive and maladaptive cellular stress responses
- (2018) Verónica Eisner et al. NATURE CELL BIOLOGY
- Cell-Autonomous Metabolic Reprogramming in Hypoxia
- (2018) Luana Schito et al. TRENDS IN CELL BIOLOGY
- The Effects of Metformin and Weight Loss on Biomarkers Associated With Breast Cancer Outcomes
- (2018) Ruth E Patterson et al. JNCI-Journal of the National Cancer Institute
- Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer
- (2018) Simon R. Lord et al. Cell Metabolism
- Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis
- (2018) Bo Zhou et al. CELL RESEARCH
- Overexpression of heat shock protein HSP90AA1 and translocase of the outer mitochondrial membrane TOM34 in HCV-induced hepatocellular carcinoma: A pilot study
- (2018) Eman A. Toraih et al. CLINICAL BIOCHEMISTRY
- Human stress-inducible Hsp70 has a high propensity to form ATP-dependent antiparallel dimers that are differentially regulated by co-chaperone binding
- (2018) Filip Trcka et al. MOLECULAR & CELLULAR PROTEOMICS
- Expression of TOMM34 and Its Clinicopathological Correlations in Urothelial Carcinoma of the Bladder
- (2018) Mohamed A. H. Ahmed et al. PATHOLOGY & ONCOLOGY RESEARCH
- Impact of Diabetes, Insulin, and Metformin Use on the Outcome of Patients With Human Epidermal Growth Factor Receptor 2–Positive Primary Breast Cancer: Analysis From the ALTTO Phase III Randomized Trial
- (2017) Amir Sonnenblick et al. JOURNAL OF CLINICAL ONCOLOGY
- Highly sensitive and specific Alu-based quantification of human cells among rodent cells
- (2017) Kodai Funakoshi et al. Scientific Reports
- Metformin as an adjuvant treatment for cancer: a systematic review and meta-analysis
- (2016) C. Coyle et al. ANNALS OF ONCOLOGY
- Metformin Targets Central Carbon Metabolism and Reveals Mitochondrial Requirements in Human Cancers
- (2016) Xiaojing Liu et al. Cell Metabolism
- NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism
- (2016) Chia-Lin Chen et al. Cell Metabolism
- Mitophagy receptors sense stress signals and couple mitochondrial dynamic machinery for mitochondrial quality control
- (2016) Hao Wu et al. FREE RADICAL BIOLOGY AND MEDICINE
- The phenomenon of acquired resistance to metformin in breast cancer cells: The interaction of growth pathways and estrogen receptor signaling
- (2016) Alexander M. Scherbakov et al. IUBMB LIFE
- ATP5A1 and ATP5B are highly expressed in glioblastoma tumor cells and endothelial cells of microvascular proliferation
- (2015) Guiyan Xu et al. JOURNAL OF NEURO-ONCOLOGY
- The Assembly and Intermolecular Properties of the Hsp70-Tomm34-Hsp90 Molecular Chaperone Complex
- (2014) Filip Trcka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Proteogenomic characterization of human colon and rectal cancer
- (2014) Bing Zhang et al. NATURE
- Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides
- (2014) Kıvanç Birsoy et al. NATURE
- Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis
- (2014) William W Wheaton et al. eLife
- TOMM34 expression in early invasive breast cancer: a biomarker associated with poor outcome
- (2012) Mohammed A. Aleskandarany et al. BREAST CANCER RESEARCH AND TREATMENT
- Metformin in cancer: translational challenges
- (2012) Ryan J O Dowling et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Investigating Metformin for Cancer Prevention and Treatment: The End of the Beginning
- (2012) Michael N. Pollak Cancer Discovery
- Cancer mortality reduction and metformin: a retrospective cohort study in type 2 diabetic patients
- (2011) S. Bo et al. DIABETES OBESITY & METABOLISM
- Sorafenib suppresses postsurgical recurrence and metastasis of hepatocellular carcinoma in an orthotopic mouse model
- (2010) Yu-Xiong Feng et al. HEPATOLOGY
- Metformin and Pathologic Complete Responses to Neoadjuvant Chemotherapy in Diabetic Patients With Breast Cancer
- (2009) Sao Jiralerspong et al. JOURNAL OF CLINICAL ONCOLOGY
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