Secondary brain injury after polystyrene microplastic-induced intracerebral hemorrhage is associated with inflammation and pyroptosis

From properties to toxicity: Comparing microplastics to other airborne microparticles

(2022) Simon Wieland et al.   JOURNAL OF HAZARDOUS MATERIALS

Persistent activation of Nrf2 in a p62-dependent non-canonical manner aggravates lead-induced kidney injury by promoting apoptosis and inhibiting autophagy

(2022) Cai-Yu Lian et al.   Journal of Advanced Research

Polystyrene microplastics up-regulates liver glutamine and glutamate synthesis and promotes autophagy-dependent ferroptosis and apoptosis in the cerebellum through the liver-brain axis

(2022) Kai Yin et al.   ENVIRONMENTAL POLLUTION

Polystyrene microplastics lead to pyroptosis and apoptosis of ovarian granulosa cells via NLRP3/Caspase-1 signaling pathway in rats

(2021) Junyu Hou et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Environmentally relevant concentration of sulfamethoxazole-induced oxidative stress-cascaded damages in the intestine of grass carp and the therapeutic application of exogenous lycopene

(2021) Yu Wang et al.   ENVIRONMENTAL POLLUTION

ROS-Induced Hepatotoxicity under Cypermethrin: Involvement of the Crosstalk between Nrf2/Keap1 and NF-κB/iκB-α Pathways Regulated by Proteasome

(2021) Hongjing Zhao et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Polystyrene microplastics induce apoptosis via ROS-mediated p53 signaling pathway in zebrafish

(2021) Sathisaran Umamaheswari et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Effect of microplastics on aquatic biota: A hormetic perspective

(2021) Tao Sun et al.   ENVIRONMENTAL POLLUTION

Photolytic degradation elevated the toxicity of polylactic acid microplastics to developing zebrafish by triggering mitochondrial dysfunction and apoptosis

(2021) Xingli Zhang et al.   JOURNAL OF HAZARDOUS MATERIALS

Glyphosate damages blood-testis barrier via NOX1-triggered oxidative stress in rats: Long-term exposure as a potential risk for male reproductive health

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Secondary PVC microplastics are more toxic than primary PVC microplastics to Oryzias melastigma embryos

(2021) Bin Xia et al.   JOURNAL OF HAZARDOUS MATERIALS

Epigenetic regulator BRD4 is involved in cadmium-induced acute kidney injury via contributing to lysosomal dysfunction, autophagy blockade and oxidative stress

(2021) Zhong-Gui Gong et al.   JOURNAL OF HAZARDOUS MATERIALS

Activation of pyroptosis and ferroptosis is involved in the hepatotoxicity induced by polystyrene microplastics in mice

(2021) Yingwen Mu et al.   CHEMOSPHERE

Nanoplastics Cause Neurobehavioral Impairments, Reproductive and Oxidative Damages, and Biomarker Responses in Zebrafish: Throwing up Alarms of Wide Spread Health Risk of Exposure

(2020) Sreeja Sarasamma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

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(2020) Marta Giacomello et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Global Perspective on Microplastics

(2020) Robert C. Hale et al.   JOURNAL OF GEOPHYSICAL RESEARCH-OCEANS

Micro-sized Microplastics Lead to Hyperactive Swimming Behaviour in Adult Zebrafish

(2020) Qiqing Chen et al.   AQUATIC TOXICOLOGY

Mechanism and regulation of pyroptosis-mediated in cancer cell death

(2020) Jianwei Ruan et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Toxicity comparison of nano-sized and micron-sized microplastics to Goldfish Carassius auratus Larvae

(2020) Hui Yang et al.   JOURNAL OF HAZARDOUS MATERIALS

AMPK, Mitochondrial Function, and Cardiovascular Disease

(2020) Shengnan Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NLRP3 inflammasome mediates 2,5-hexanedione-induced neurotoxicity through regulation of macrophage infiltration in rats

(2020) Ruixue Huang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Exposure to polystyrene microplastics induced gene modulated biological responses in zebrafish (Danio rerio)

(2020) Sathisaran Umamaheswari et al.   CHEMOSPHERE

The interactions between microplastic polyvinyl chloride and marine diatoms: Physiological, morphological, and growth effects

(2020) Shuai Wang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Neurotoxic potential of polystyrene nanoplastics in primary cells originating from mouse brain

(2020) Byung-Kwon Jung et al.   NEUROTOXICOLOGY

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(2020) Allan Peter Davis et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial Fusion: The Machineries In and Out

(2020) Song Gao et al.   TRENDS IN CELL BIOLOGY

TREM-1 Exacerbates Neuroinflammatory Injury via NLRP3 Inflammasome-Mediated Pyroptosis in Experimental Subarachnoid Hemorrhage

(2020) Pengfei Xu et al.   Translational Stroke Research

In vitro chemical and physical toxicities of polystyrene microfragments in human-derived cells

(2020) Daheui Choi et al.   JOURNAL OF HAZARDOUS MATERIALS

Role and Mechanisms of Cytokines in the Secondary Brain Injury After Intracerebral Hemorrhage

(2019) Huimin Zhu et al.   PROGRESS IN NEUROBIOLOGY

Acute toxic effects of polyethylene microplastic on adult zebrafish

(2019) Chu Wa Mak et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Microplastic ingestion cause intestinal lesions in the intertidal fish Girella laevifrons

(2019) C. Ahrendt et al.   MARINE POLLUTION BULLETIN

Fiery Cell Death: Pyroptosis in the Central Nervous System

(2019) Brienne A. McKenzie et al.   TRENDS IN NEUROSCIENCES

Melatonin prevents Drp1-mediated mitochondrial fission in diabetic hearts through SIRT1-PGC1α pathway

(2018) Mingge Ding et al.   JOURNAL OF PINEAL RESEARCH

Targeting the NLRP3 inflammasome in inflammatory diseases

(2018) Matthew S. J. Mangan et al.   NATURE REVIEWS DRUG DISCOVERY

Programmed Cell Death after Intracerebral Hemorrhage

(2018) Tobias Bobinger et al.   Current Neuropharmacology

Marine microplastics bound dioxin-like chemicals: Model explanation and risk assessment

(2018) Qiqing Chen et al.   JOURNAL OF HAZARDOUS MATERIALS

The mitochondrial UPR: mechanisms, physiological functions and implications in ageing

(2017) Tomer Shpilka et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial energetics in the kidney

(2017) Pallavi Bhargava et al.   Nature Reviews Nephrology

Interactions of microplastic debris throughout the marine ecosystem

(2017) Tamara S. Galloway et al.   Nature Ecology & Evolution

Uptake and Accumulation of Polystyrene Microplastics in Zebrafish (Danio rerio) and Toxic Effects in Liver

(2016) Yifeng Lu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

343 Mitochondrial dysfunction activates the AMPK signaling and autophagy to promote cell survival

(2016) B. Zhao et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Mitofusins, from Mitochondria to Metabolism

(2016) Emilie Schrepfer et al.   MOLECULAR CELL

ROS-Mediated NLRP3 Inflammasome Activation in Brain, Heart, Kidney, and Testis Ischemia/Reperfusion Injury

(2016) Letteria Minutoli et al.   Oxidative Medicine and Cellular Longevity

Early Erythrolysis in the Hematoma After Experimental Intracerebral Hemorrhage

(2016) Ge Dang et al.   Translational Stroke Research

Molecular mechanisms regulating NLRP3 inflammasome activation

(2015) Eun-Kyeong Jo et al.   Cellular & Molecular Immunology

MicroRNA-223 regulates inflammation and brain injury via feedback to NLRP3 inflammasome after intracerebral hemorrhage

(2015) Zhao Yang et al.   MOLECULAR IMMUNOLOGY

NLRP3 inflammasome contributes to inflammation after intracerebral hemorrhage

(2013) Qingyi Ma et al.   ANNALS OF NEUROLOGY

Insulin Stimulates Mitochondrial Fusion and Function in Cardiomyocytes via the Akt-mTOR-NF B-Opa-1 Signaling Pathway

(2013) V. Parra et al.   DIABETES

Policy: Classify plastic waste as hazardous

(2013) Chelsea M. Rochman et al.   NATURE

Inflammation in intracerebral hemorrhage: From mechanisms to clinical translation

(2013) Yu Zhou et al.   PROGRESS IN NEUROBIOLOGY

Thrombin and hemin as central factors in the mechanisms of intracerebral hemorrhage–induced secondary brain injury and as potential targets for intervention

(2012) Ranjith Babu et al.   Neurosurgical Focus

Molecular Pathophysiology of Cerebral Hemorrhage

(2011) Jaroslaw Aronowski et al.   STROKE

Ac-YVAD-CMK Decreases Blood–Brain Barrier Degradation by Inhibiting Caspase-1 Activation of Interleukin-1β in Intracerebral Hemorrhage Mouse Model

(2009) Bihua Wu et al.   Translational Stroke Research

AMPK and PPARδ Agonists Are Exercise Mimetics

(2008) Vihang A. Narkar et al.   CELL