Bone marrow and periosteal skeletal stem/progenitor cells make distinct contributions to bone maintenance and repair

A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis

(2021) Bo Shen et al.   NATURE

Heterogeneity of murine periosteum progenitors involved in fracture healing

(2021) Brya G Matthews et al.   eLife

The characterization of distinct populations of murine skeletal cells that have different roles in B lymphopoiesis

(2021) Alanna Claire Green et al.   BLOOD

Tracing the skeletal progenitor transition during postnatal bone formation

(2021) Hui Sophie Shu et al.   Cell Stem Cell

Aged skeletal stem cells generate an inflammatory degenerative niche

(2021) Thomas H. Ambrosi et al.   NATURE

Distinct skeletal stem cell types orchestrate long bone skeletogenesis

(2021) Thomas H Ambrosi et al.   eLife

A bone-specific adipogenesis pathway in fat-free mice defines key origins and adaptations of bone marrow adipocytes with age and disease

(2021) Xiao Zhang et al.   eLife

Single‐cell transcriptomics of LepR‐positive skeletal cells reveals heterogeneous stress‐dependent stem and progenitor pools

(2021) Chunyang Mo et al.   EMBO JOURNAL

A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration

(2020) Yuki Matsushita et al.   Nature Communications

Skeletal stem cells: insights into maintaining and regenerating the skeleton

(2020) Maxwell A. Serowoky et al.   DEVELOPMENT

Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment

(2020) Leilei Zhong et al.   eLife

A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia

(2019) Ninib Baryawno et al.   CELL

The bone marrow microenvironment at single-cell resolution

(2019) Anastasia N. Tikhonova et al.   NATURE

Sox9+ messenger cells orchestrate large-scale skeletal regeneration in the mammalian rib

(2019) Stephanie T Kuwahara et al.   eLife

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life

(2019) Kyriel M. Pineault et al.   Nature Communications

Identification of Functionally Distinct Mx1+αSMA+ Periosteal Skeletal Stem Cells

(2019) Laura C. Ortinau et al.   Cell Stem Cell

Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization

(2019) Chiara Baccin et al.   NATURE CELL BIOLOGY

Periosteum contains skeletal stem cells with high bone regenerative potential controlled by Periostin

(2018) Oriane Duchamp de Lageneste et al.   Nature Communications

Discovery of a periosteal stem cell mediating intramembranous bone formation

(2018) Shawon Debnath et al.   NATURE

Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents

(2018) Robert L Zondervan et al.   Jove-Journal of Visualized Experiments

Bone marrow adipocytes promote the regeneration of stem cells and haematopoiesis by secreting SCF

(2017) Bo O. Zhou et al.   NATURE CELL BIOLOGY

Gli1 identifies osteogenic progenitors for bone formation and fracture repair

(2017) Yu Shi et al.   Nature Communications

Osteogenic potential of alpha smooth muscle actin expressing muscle resident progenitor cells

(2016) Brya G. Matthews et al.   BONE

Clec11a/osteolectin is an osteogenic growth factor that promotes the maintenance of the adult skeleton

(2016) Rui Yue et al.   eLife

Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential

(2015) Daniel L. Worthley et al.   CELL

Identification and Specification of the Mouse Skeletal Stem Cell

(2015) Charles K.F. Chan et al.   CELL

Skeletal stem cells

(2015) P. Bianco et al.   DEVELOPMENT

Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal

(2015) Melih Acar et al.   NATURE

Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity

(2015) Elise Jeffery et al.   NATURE CELL BIOLOGY

The suture provides a niche for mesenchymal stem cells of craniofacial bones

(2015) Hu Zhao et al.   NATURE CELL BIOLOGY

Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow

(2014) Bo O. Zhou et al.   Cell Stem Cell

Vasculature-Associated Cells Expressing Nestin in Developing Bones Encompass Early Cells in the Osteoblast and Endothelial Lineage

(2014) Noriaki Ono et al.   DEVELOPMENTAL CELL

Osterix Marks Distinct Waves of Primitive and Definitive Stromal Progenitors during Bone Marrow Development

(2014) Toshihide Mizoguchi et al.   DEVELOPMENTAL CELL

Homeostasis and Effector Function of Lymphopenia-Induced "Memory-Like" T Cells in Constitutively T Cell-Depleted Mice

(2014) D. Voehringer et al.   JOURNAL OF IMMUNOLOGY

Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone

(2014) Anjali P. Kusumbe et al.   NATURE

A subset of chondrogenic cells provides early mesenchymal progenitors in growing bones

(2014) Noriaki Ono et al.   NATURE CELL BIOLOGY

Periosteal cells are a major source of soft callus in bone fracture

(2013) Hiroki Murao et al.   JOURNAL OF BONE AND MINERAL METABOLISM

CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance

(2013) Adam Greenbaum et al.   NATURE

Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

(2013) Lei Ding et al.   NATURE

Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration

(2012) Dongsu Park et al.   Cell Stem Cell

Endothelial and perivascular cells maintain haematopoietic stem cells

(2012) Lei Ding et al.   NATURE

Concise Review: The Periosteum: Tapping into a Reservoir of Clinically Useful Progenitor Cells

(2012) Hana Chang et al.   Stem Cells Translational Medicine

Transcriptional Control of Adipose Lipid Handling by IRF4

(2011) Jun Eguchi et al.   Cell Metabolism

Osteoblast Precursors, but Not Mature Osteoblasts, Move into Developing and Fractured Bones along with Invading Blood Vessels

(2010) Christa Maes et al.   DEVELOPMENTAL CELL

The Essential Functions of Adipo-osteogenic Progenitors as the Hematopoietic Stem and Progenitor Cell Niche

(2010) Yoshiki Omatsu et al.   IMMUNITY

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

(2010) Simón Méndez-Ferrer et al.   NATURE

Mice expressing GFP and CreER in osteochondro progenitor cells in the periosteum

(2009) Aya Kawanami et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow

(2009) Satoru Morikawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

The Loss of Nf1 Transiently Promotes Self-Renewal but Not Tumorigenesis by Neural Crest Stem Cells

(2008) Nancy M. Joseph et al.   CANCER CELL

Embryonic origin and Hox status determine progenitor cell fate during adult bone regeneration

(2008) P. Leucht et al.   DEVELOPMENT

Efficient temporally-controlled targeted mutagenesis in smooth muscle cells of the adult mouse

(2008) Olivia Wendling et al.   GENESIS

Skeletal Cell Fate Decisions Within Periosteum and Bone Marrow During Bone Regeneration

(2008) Céline Colnot   JOURNAL OF BONE AND MINERAL RESEARCH