Mitochondrial dynamics maintain muscle stem cell regenerative competence throughout adult life by regulating metabolism and mitophagy

Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults

(2022) Sophia Liu et al.   JAMA Network Open

Deletion of the mitochondria-shaping protein Opa1 during early thymocyte maturation impacts mature memory T cell metabolism

(2021) Mauro Corrado et al.   CELL DEATH AND DIFFERENTIATION

Grx2 Regulates Skeletal Muscle Mitochondrial Structure and Autophagy

(2021) Ava Liaghati et al.   Frontiers in Physiology

Urolithin A improves muscle function by inducing mitophagy in muscular dystrophy

(2021) Peiling Luan et al.   Science Translational Medicine

Mitochondrial fusion and fission: The fine‐tune balance for cellular homeostasis

(2021) Mary Adebayo et al.   FASEB JOURNAL

Stem cell aging in the skeletal muscle: The importance of communication

(2021) Xiaotong Hong et al.   AGEING RESEARCH REVIEWS

Control of satellite cell function in muscle regeneration and its disruption in ageing

(2021) Pedro Sousa-Victor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The cell biology of mitochondrial membrane dynamics

(2020) Marta Giacomello et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Muscle stem cell aging: identifying ways to induce tissue rejuvenation

(2020) Pedro Sousa-Victor et al.   MECHANISMS OF AGEING AND DEVELOPMENT

FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age

(2020) Laura García-Prat et al.   NATURE CELL BIOLOGY

Pathway enrichment analysis and visualization of omics data using g:Profiler, GSEA, Cytoscape and EnrichmentMap

(2019) Jüri Reimand et al.   Nature Protocols

Remodeling of epigenome and transcriptome landscapes with aging in mice reveals widespread induction of inflammatory responses

(2019) Bérénice A. Benayoun et al.   GENOME RESEARCH

ER and Nutrient Stress Promote Assembly of Respiratory Chain Supercomplexes through the PERK-eIF2α Axis

(2019) Eduardo Balsa et al.   MOLECULAR CELL

g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)

(2019) Uku Raudvere et al.   NUCLEIC ACIDS RESEARCH

Age-Related Gene Expression Signature in Rats Demonstrate Early, Late, and Linear Transcriptional Changes from Multiple Tissues

(2019) Tea Shavlakadze et al.   Cell Reports

Mitofusin gain and loss of function drive pathogenesis in Drosophila models of CMT2A neuropathy

(2018) Najla El Fissi et al.   EMBO REPORTS

Mitochondrial Dynamics at the Interface of Immune Cell Metabolism and Function

(2018) Angelika S. Rambold et al.   TRENDS IN IMMUNOLOGY

The AMPK/p27 Kip1 Axis Regulates Autophagy/Apoptosis Decisions in Aged Skeletal Muscle Stem Cells

(2018) James P. White et al.   Stem Cell Reports

Distinct metabolic states govern skeletal muscle stem cell fates during prenatal and postnatal myogenesis

(2018) Francesca Pala et al.   JOURNAL OF CELL SCIENCE

The machineries, regulation and cellular functions of mitochondrial calcium

(2018) Carlotta Giorgi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration

(2018) A. Sahu et al.   Nature Communications

Transcriptional Signatures of Aging

(2017) R. Stegeman et al.   JOURNAL OF MOLECULAR BIOLOGY

AMPK Promotes Autophagy by Facilitating Mitochondrial Fission

(2016) Chen-Song Zhang et al.   Cell Metabolism

Autophagy maintains stemness by preventing senescence

(2016) Laura García-Prat et al.   NATURE

Metabolic regulation of stem cell function in tissue homeostasis and organismal ageing

(2016) Navdeep S. Chandel et al.   NATURE CELL BIOLOGY

Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents

(2016) Dongryeol Ryu et al.   NATURE MEDICINE

NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

(2016) H. Zhang et al.   SCIENCE

AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

(2016) E. Q. Toyama et al.   SCIENCE

The Spectrum of Mitochondrial Ultrastructural Defects in Mitochondrial Myopathy

(2016) Amy E. Vincent et al.   Scientific Reports

Mitochondrial ROS Signaling in Organismal Homeostasis

(2015) Gerald S. Shadel et al.   CELL

Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization

(2015) H Li et al.   CELL DEATH AND DIFFERENTIATION

The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells

(2015) James G. Ryall et al.   Cell Stem Cell

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Induction of autophagy supports the bioenergetic demands of quiescent muscle stem cell activation

(2014) Ann H Tang et al.   EMBO JOURNAL

Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases

(2014) C. Franceschi et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Dynamics of Mitochondrial DNA Nucleoids Regulated by Mitochondrial Fission Is Essential for Maintenance of Homogeneously Active Mitochondria during Neonatal Heart Development

(2014) Takaya Ishihara et al.   MOLECULAR AND CELLULAR BIOLOGY

mTORC1 controls the adaptive transition of quiescent stem cells from G0 to GAlert

(2014) Joseph T. Rodgers et al.   NATURE

Geriatric muscle stem cells switch reversible quiescence into senescence

(2014) Pedro Sousa-Victor et al.   NATURE

Ensembl 2015

(2014) Fiona Cunningham et al.   NUCLEIC ACIDS RESEARCH

Quality matters: how does mitochondrial network dynamics and quality control impact on mtDNA integrity?

(2014) K. B. Busch et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

In Vitro-Reconstituted Nucleoids Can Block Mitochondrial DNA Replication and Transcription

(2014) Géraldine Farge et al.   Cell Reports

Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency

(2013) Sara Cogliati et al.   CELL

A Subpopulation of Adult Skeletal Muscle Stem Cells Retains All Template DNA Strands after Cell Division

(2012) Pierre Rocheteau et al.   CELL

Mitochondria as sensors and regulators of calcium signalling

(2012) Rosario Rizzuto et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial Fission, Fusion, and Stress

(2012) R. J. Youle et al.   SCIENCE

PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria

(2012) Kei Okatsu et al.   Nature Communications

Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health

(2011) David C. Chan   Annual Review of Genetics

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Parkin interacts with Klokin1 for mitochondrial import and maintenance of membrane potential

(2011) Yukiko Kuroda et al.   HUMAN MOLECULAR GENETICS

p38/MKP-1–regulated AKT coordinates macrophage transitions and resolution of inflammation during tissue repair

(2011) Eusebio Perdiguero et al.   JOURNAL OF CELL BIOLOGY

Short Telomeres and Stem Cell Exhaustion Model Duchenne Muscular Dystrophy in mdx/mTR Mice

(2010) Alessandra Sacco et al.   CELL

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

(2010) Noriyuki Matsuda et al.   JOURNAL OF CELL BIOLOGY

Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation

(2010) Daniele Merico et al.   PLoS One

Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes

(2010) Robert B. Hamanaka et al.   TRENDS IN BIOCHEMICAL SCIENCES

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Biomarker system for studying muscle, stem cells, and cancer in vivo

(2009) Koichi Nishijo et al.   FASEB JOURNAL

Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

(2009) Naotada Ishihara et al.   NATURE CELL BIOLOGY

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Preventing Mitochondrial Fission Impairs Mitochondrial Function and Leads to Loss of Mitochondrial DNA

(2008) Philippe A. Parone et al.   PLoS One