Intestinal mucin is a chaperone of multivalent copper

Helical self-assembly of a mucin segment suggests an evolutionary origin for von Willebrand factor tubules

(2022) Gabriel Javitt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Principles and practice of determining metal–protein affinities

(2021) Tessa R. Young et al.   BIOCHEMICAL JOURNAL

Trefoil Factor Family (TFF) Peptides and their Different Roles in the Mucosal Innate Immune Defense and More: An Update

(2021) Werner Hoffmann   CURRENT MEDICINAL CHEMISTRY

The Relationship between Mucins and Ulcerative Colitis: A Systematic Review

(2021) Esther Bankole et al.   Journal of Clinical Medicine

The mutational constraint spectrum quantified from variation in 141,456 humans

(2020) Konrad J. Karczewski et al.   NATURE

Copper Homeostasis in Mammals, with Emphasis on Secretion and Excretion. A Review

(2020) Maria C. Linder   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Copper metabolism as a unique vulnerability in cancer

(2020) Vinit C. Shanbhag et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Assembly Mechanism of Mucin and von Willebrand Factor Polymers

(2020) Gabriel Javitt et al.   CELL

Mucus barrier, mucins and gut microbiota: the expected slimy partners?

(2020) Paola Paone et al.   GUT

The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis

(2019) Xianchi Dong et al.   BLOOD

X-ray structures of the high-affinity copper transporter Ctr1

(2019) Feifei Ren et al.   Nature Communications

Copper Transport and Disease: What Can We Learn from Organoids?

(2019) Hannah Pierson et al.   Annual Review of Nutrition

Intestinal Gel-Forming Mucins Polymerize by Disulfide-Mediated Dimerization of D3 Domains

(2019) Gabriel Javitt et al.   JOURNAL OF MOLECULAR BIOLOGY

Copper trafficking in eukaryotic systems: current knowledge from experimental and computational efforts

(2019) Alessandra Magistrato et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Redox active metals in neurodegenerative diseases

(2019) Karla Acevedo et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

The Impact of Dietary Transition Metals on Host-Bacterial Interactions

(2018) Christopher A. Lopez et al.   Cell Host & Microbe

Defensins, lectins, mucins, and secretory immunoglobulin A: microbe-binding biomolecules that contribute to mucosal immunity in the human gut

(2016) Phoom Chairatana et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Kβ Valence to Core X-ray Emission Studies of Cu(I) Binding Proteins with Mixed Methionine – Histidine Coordination. Relevance to the Reactivity of the M- and H-sites of Peptidylglycine Monooxygenase

(2016) Vlad Martin-Diaconescu et al.   INORGANIC CHEMISTRY

Ceruloplasmin and other copper binding components of blood plasma and their functions: an update

(2016) M. C. Linder   Metallomics

Intestinal MUC2 Mucin Supramolecular Topology by Packing and Release Resting on D3 Domain Assembly

(2014) Harriet E. Nilsson et al.   JOURNAL OF MOLECULAR BIOLOGY

Tracking metal ions through a Cu/Ag efflux pump assigns the functional roles of the periplasmic proteins

(2014) K. N. Chacon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbial-induced meprin   cleavage in MUC2 mucin and a functional CFTR channel are required to release anchored small intestinal mucus

(2014) A. Schutte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluation of quantitative probes for weaker Cu(i) binding sites completes a set of four capable of detecting Cu(i) affinities from nanomolar to attomolar

(2013) Zhiguang Xiao et al.   Metallomics

Charting the travels of copper in eukaryotes from yeast to mammals

(2012) Tracy Nevitt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Thermodynamic study of Cu2+ binding to the DAHK and GHK peptides by isothermal titration calorimetry (ITC) with the weaker competitor glycine

(2011) Ana Trapaidze et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Coordination chemistry of copper proteins: How nature handles a toxic cargo for essential function

(2011) Jeffrey T. Rubino et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Mucin dynamics and enteric pathogens

(2011) Michael A. McGuckin et al.   NATURE REVIEWS MICROBIOLOGY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Copper Metallochaperones

(2010) Nigel J. Robinson et al.   Annual Review of Biochemistry

The Cardiac Copper Chaperone Proteins Sco1 and CCS are Up-Regulated, but Cox 1 and Cox4 are Down-Regulated, by Copper Deficiency

(2010) Jean Getz et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Copper binds the carboxy-terminus of trefoil protein 1 (TFF1), favoring its homodimerization and motogenic activity

(2010) Alessandra Tosco et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ctr1 Is an Apical Copper Transporter in Mammalian Intestinal Epithelial Cellsin VivoThat Is Controlled at the Level of Protein Stability

(2010) Yasuhiro Nose et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein-folding location can regulate manganese-binding versus copper- or zinc-binding

(2008) Steve Tottey et al.   NATURE