Interleukin-15 enhances the proliferation, stimulatory phenotype, and antitumor effector functions of human gamma delta T cells

CD56-positive lymphocyte infiltration in relation to human papillomavirus association and prognostic significance in oropharyngeal squamous cell carcinoma

(2016) Steffen Wagner et al.   INTERNATIONAL JOURNAL OF CANCER

CD19 CAR–T cells of defined CD4+:CD8+ composition in adult B cell ALL patients

(2016) Cameron J. Turtle et al.   JOURNAL OF CLINICAL INVESTIGATION

Bisphosphonates for cancer treatment: Mechanisms of action and lessons from clinical trials

(2016) Heleen H. Van Acker et al.   PHARMACOLOGY & THERAPEUTICS

Acute myeloid leukemia-Major progress over four decades and glimpses into the future

(2015) Hagop Kantarjian   AMERICAN JOURNAL OF HEMATOLOGY

Gamma Delta T Cell Reconstitution Is Associated with Fewer Infections and Improved Event-Free Survival after Hematopoietic Stem Cell Transplantation for Pediatric Leukemia

(2015) Ross Perko et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

   T-cell reconstitution after HLA-haploidentical hematopoietic transplantation depleted of TCR-  +/CD19+ lymphocytes

(2015) I. Airoldi et al.   BLOOD

Immunotherapy in acute myeloid leukemia

(2015) Dolores A. Grosso et al.   CANCER

Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential

(2015) Padmanee Sharma et al.   CELL

The promise of γδ T cells and the γδ T cell receptor for cancer immunotherapy

(2015) Mateusz Legut et al.   Cellular & Molecular Immunology

Interleukin-15: New kid on the block for antitumor combination therapy

(2015) Johan M.J. Van den Bergh et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Memory T cell–driven differentiation of naive cells impairs adoptive immunotherapy

(2015) Christopher A. Klebanoff et al.   JOURNAL OF CLINICAL INVESTIGATION

Redistribution, Hyperproliferation, Activation of Natural Killer Cells and CD8 T Cells, and Cytokine Production During First-in-Human Clinical Trial of Recombinant Human Interleukin-15 in Patients With Cancer

(2015) Kevin C. Conlon et al.   JOURNAL OF CLINICAL ONCOLOGY

The prognostic landscape of genes and infiltrating immune cells across human cancers

(2015) Andrew J Gentles et al.   NATURE MEDICINE

The Role of Gamma Delta T Cells in Haematopoietic Stem Cell Transplantation

(2015) L. Minculescu et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory

(2015) Giacomo Oliveira et al.   Science Translational Medicine

γδ T cells and epigenetic drugs: A useful merger in cancer immunotherapy?

(2015) Jaydeep Bhat et al.   OncoImmunology

Empowering gamma delta T cells with antitumor immunity by dendritic cell-based immunotherapy

(2015) Heleen H Van Acker et al.   OncoImmunology

Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15

(2014) Y. Xu et al.   BLOOD

Direct involvement of CD56 in cytokine-induced killer–mediated lysis of CD56+ hematopoietic target cells

(2014) Rut Valgardsdottir et al.   EXPERIMENTAL HEMATOLOGY

Vaccination with tumor cells expressing IL-15 and IL-15Rα inhibits murine breast and prostate cancer

(2014) J C Morris et al.   GENE THERAPY

Human    Thymocytes Are Functionally Immature and Differentiate into Cytotoxic Type 1 Effector T Cells upon IL-2/IL-15 Signaling

(2014) J. C. Ribot et al.   JOURNAL OF IMMUNOLOGY

Management of older or unfit patients with acute myeloid leukemia

(2014) R B Walter et al.   LEUKEMIA

Clinical Applications of Gamma Delta T Cells with Multivalent Immunity

(2014) Drew C. Deniger et al.   Frontiers in Immunology

γδ T cells for cancer immunotherapy

(2014) Jonathan PH Fisher et al.   OncoImmunology

Stress-related and homeostatic cytokines regulate Vγ9Vδ2 T-cell surveillance of mevalonate metabolism

(2014) Georg Gruenbacher et al.   OncoImmunology

Ex vivo characterization of γδ T-cell repertoire in patients after adoptive transfer of Vγ9Vδ2 T cells expressing the interleukin-2 receptor β-chain and the common γ-chain

(2013) Takamichi Izumi et al.   CYTOTHERAPY

The use of endogenous T cells for adoptive transfer

(2013) Cassian Yee   IMMUNOLOGICAL REVIEWS

CD56 marks human dendritic cell subsets with cytotoxic potential

(2013) Dessie Roothans et al.   OncoImmunology

Tumor cell recognition by γδ T lymphocytes

(2013) Daniel V. Correia et al.   OncoImmunology

Human plasmacytoid dendritic cells are equipped with antigen-presenting and tumoricidal capacities

(2012) J. Tel et al.   BLOOD

IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors

(2012) N. Cieri et al.   BLOOD

Human cord blood γδ T cells expressing public Vγ2 chains dominate the response to bisphosphonate plus interleukin-15

(2012) Cristiana Cairo et al.   IMMUNOLOGY

Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15

(2012) Aaron M Ring et al.   NATURE IMMUNOLOGY

Interleukin-15-Induced CD56+ Myeloid Dendritic Cells Combine Potent Tumor Antigen Presentation with Direct Tumoricidal Potential

(2012) Sébastien Anguille et al.   PLoS One

IL-15 administered by continuous infusion to rhesus macaques induces massive expansion of CD8+ T effector memory population in peripheral blood

(2011) M. C. Sneller et al.   BLOOD

Clinical evaluation of autologous gamma delta T cell-based immunotherapy for metastatic solid tumours

(2011) A J Nicol et al.   BRITISH JOURNAL OF CANCER

γδ T-APCs: a novel tool for immunotherapy?

(2011) Bernhard Moser et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

How tumors might withstand γδ T-cell attack

(2011) Aude-Hélène Capietto et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A human memory T cell subset with stem cell–like properties

(2011) Luca Gattinoni et al.   NATURE MEDICINE

Interleukin-15 biology and its therapeutic implications in cancer

(2011) Jason C. Steel et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A phase I study of adoptive immunotherapy for recurrent non-small-cell lung cancer patients with autologous γδ T cells☆☆☆

(2010) Jun Nakajima et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

Naturally Activated V 4    T Cells Play a Protective Role in Tumor Immunity through Expression of Eomesodermin

(2010) W. He et al.   JOURNAL OF IMMUNOLOGY

IL-15 produced and trans-presented by DCs underlies homeostatic competition between CD8 and    T cells in vivo

(2009) J.-s. Do et al.   BLOOD

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

(2009) H. Dohner et al.   BLOOD

Large scale expansion of Vγ9Vδ2 T lymphocytes from human peripheral blood mononuclear cells after a positive selection using MACS “TCR γ/δ + T cell isolation kit”

(2009) Samuel Salot et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Chemokine Receptors Expression and Migration Potential of Tumor-infiltrating and Peripheral-expanded Vγ9Vδ2 T Cells From Renal Cell Carcinoma Patients

(2009) Emilie Viey et al.   JOURNAL OF IMMUNOTHERAPY

Peripheral blood monocytes are responsible for γδ T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP

(2008) Anke J. Roelofs et al.   BRITISH JOURNAL OF HAEMATOLOGY

Phase-I study of Innacell γδ™, an autologous cell-therapy product highly enriched in γ9δ2 T lymphocytes, in combination with IL-2, in patients with metastatic renal cell carcinoma

(2008) Jaafar Bennouna et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Isopentenyl Pyrophosphate-Activated CD56+    T Lymphocytes Display Potent Antitumor Activity toward Human Squamous Cell Carcinoma

(2008) A. A.Z. Alexander et al.   CLINICAL CANCER RESEARCH

Twelve immunotherapy drugs that could cure cancers

(2008) Martin A. ‘Mac’ Cheever   IMMUNOLOGICAL REVIEWS