A newly synthesized 17-epi-NeuroProtectin D1/17-epi-Protectin D1: Authentication and functional regulation of Inflammation-Resolution

Cerebrospinal Fluid Profile of Lipid Mediators in Alzheimer’s Disease

(2022) Khanh V. Do et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Intranasal delivery of pro-resolving lipid mediators rescues memory and gamma oscillation impairment in AppNL-G-F/NL-G-F mice

(2022) Ceren Emre et al.   Communications Biology

A Systematic Review of the Impact of the First Year of COVID-19 on Obesity Risk Factors: A Pandemic Fueling a Pandemic?

(2022) Natasha Faye Daniels et al.   Current Developments in Nutrition

Neuroprotectin D1 Attenuates Blast Overpressure Induced Reactive Microglial Cells in the Cochlea

(2021) José David Ríos et al.   LARYNGOSCOPE

Immunomodulatory lipid mediator profiling of cerebrospinal fluid following surgery in older adults

(2021) Niccolò Terrando et al.   Scientific Reports

Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice

(2021) Sangsu Bang et al.   Nature Communications

In Vitro Biosynthetic Pathway Investigations of Neuroprotectin D1 (NPD1) and Protectin DX (PDX) by Human 12-Lipoxygenase, 15-Lipoxygenase-1, and 15-Lipoxygenase-2

(2021) Wan-Chen Tsai et al.   BIOCHEMISTRY

Protectin D1 reduces imiquimod-induced psoriasiform skin inflammation

(2021) Kyung-Duck Park et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Human leukocytes selectively convert 4S,5S-epoxy-resolvin to resolvin D3, resolvin D4, and a cys-resolvin isomer

(2021) Ashley E. Shay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pro‐resolving mediator protectin D1 promotes epimorphic regeneration by controlling immune cell function in vertebrates

(2020) Mai Nguyen‐Chi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Distinct Profiles of Specialized Pro-resolving Lipid Mediators and Corresponding Receptor Gene Expression in Periodontal Inflammation

(2020) Brittney Ferguson et al.   Frontiers in Immunology

Dexamethasone, pro‐resolving lipid mediators and resolution of inflammation in COVID‐19

(2020) Evangelos Andreakos et al.   ALLERGY

Pseudomonas aeruginosa Lipoxygenase LoxA Contributes to Lung Infection by Altering the Host Immune Lipid Signaling

(2019) Eric Morello et al.   Frontiers in Microbiology

Rapid Metabolization of Protectin D1 by β-Oxidation of Its Polar Head Chain

(2019) Laurence Balas et al.   JOURNAL OF MEDICINAL CHEMISTRY

GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain

(2018) Sangsu Bang et al.   JOURNAL OF CLINICAL INVESTIGATION

Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators

(2018) Charles N. Serhan et al.   JOURNAL OF CLINICAL INVESTIGATION

Leukotriene biosynthetic enzymes as therapeutic targets

(2018) Jesper Z. Haeggström   JOURNAL OF CLINICAL INVESTIGATION

Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer’s Disease

(2018) Ju Youn Lee et al.   Nature Communications

Synthesis of protectin D1 analogs: novel pro-resolution and radiotracer agents

(2018) J. E. Tungen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cutting Edge: Human Vagus Produces Specialized Proresolving Mediators of Inflammation with Electrical Stimulation Reducing Proinflammatory Eicosanoids

(2018) Charles N. Serhan et al.   JOURNAL OF IMMUNOLOGY

Crystal Structure of Aspirin-Acetylated Human Cyclooxygenase-2: Insight into the Formation of Products with Reversed Stereochemistry

(2016) Michael J. Lucido et al.   BIOCHEMISTRY

Dihydroxylated E,E,Z-docosatrienes. An overview of their synthesis and biological significance

(2016) Laurence Balas et al.   PROGRESS IN LIPID RESEARCH

Role of omega-3 PUFA-derived mediators, the protectins, in influenza virus infection

(2015) Yumiko Imai   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Synthesis of the 16S,17S-Epoxyprotectin Intermediate in the Biosynthesis of Protectins by Human Macrophages

(2015) Marius Aursnes et al.   JOURNAL OF NATURAL PRODUCTS

Human milk proresolving mediators stimulate resolution of acute inflammation

(2015) H Arnardottir et al.   Mucosal Immunology

Neuroprotectin/protectin D1: endogenous biosynthesis and actions on diabetic macrophages in promoting wound healing and innervation impaired by diabetes

(2014) Song Hong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Total Synthesis of Neuroprotectin D1 Analogues Derived from Omega-6 Docosapentaenoic Acid (DPA) and Adrenic Acid (AdA) from a Common Pivotal, Late-Stage Intermediate

(2014) Gandrath Dayaker et al.   JOURNAL OF ORGANIC CHEMISTRY

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza

(2013) Masayuki Morita et al.   CELL

Novel aspirin-triggered neuroprotectin D1 attenuates cerebral ischemic injury after experimental stroke

(2012) Nicolas G. Bazan et al.   EXPERIMENTAL NEUROLOGY

Dysregulated synthesis of protectin D1 in eosinophils from patients with severe asthma

(2012) Jun Miyata et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Stereocontrolled total synthesis of Neuroprotectin D1/Protectin D1 and its aspirin-triggered stereoisomer

(2012) Nicos A. Petasis et al.   TETRAHEDRON LETTERS

Resolvins and Protectins in Inflammation Resolution

(2011) Charles N. Serhan et al.   CHEMICAL REVIEWS

Novel Proresolving Aspirin-Triggered DHA Pathway

(2011) Charles N. Serhan et al.   CHEMISTRY & BIOLOGY

Resolving TRPV1- and TNF- -Mediated Spinal Cord Synaptic Plasticity and Inflammatory Pain with Neuroprotectin D1

(2011) C.-K. Park et al.   JOURNAL OF NEUROSCIENCE