Atroposelective Access to 1,3‐Oxazepine‐Containing Bridged Biaryls via Carbene‐Catalyzed Desymmetrization of Imines

Catalytic atroposelective synthesis of axially chiral benzonitriles via chirality control during bond dissociation and CN group formation

(2022) Ya Lv et al.   Nature Communications

Atroposelective Construction of Nine‐Membered Carbonate Bridged Biaryls

(2022) Shiqi Jia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Carbene‐Catalyzed Oxidation of Functionalized Aldimines as 1,4‐Dipoles

(2021) Guanjie Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carbene‐Catalyzed Activation of Remote Nitrogen Atoms of (benz)imidazole‐derived aldimines for Enantioselective Synthesis of Heterocycles

(2021) Xing Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N‐Heterocyclic Carbene‐Catalyzed Atroposelective Annulation for Access to Thiazine Derivatives with C‐N Axial Chirality

(2021) Tingting Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NHC‐Catalyzed Desymmetrization of N‐Aryl Maleimides Leading to the Atroposelective Synthesis of N‐Aryl Succinimides

(2021) Soumen Barik et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Axially Chiral Benzothiophene/Benzofuran‐Fused Biaryls by N‐Heterocyclic Carbene Catalyzed Arene Formation

(2021) Chun‐Lin Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Synthesis of Silicon‐Stereogenic Dihydrodibenzosilines: Silicon Central‐to‐Axial Chirality Relay

(2021) Yonghong Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in Catalytic Asymmetric Construction of Atropisomers

(2021) Jun Kee Cheng et al.   CHEMICAL REVIEWS

Atroposelective Synthesis of Axially Chiral 4-Aryl α-Carbolines via N-Heterocyclic Carbene Catalysis

(2021) Rui Ma et al.   ORGANIC LETTERS

Carbene‐Catalyzed Asymmetric Construction of Atropisomers

(2021) Runjiang Song et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Progress toward the Construction of Axially Chiral Molecules Catalyzed by an N-heterocyclic Carbene

(2021) Jiaming Wang et al.   ACS Catalysis

Understanding chemical reactivity using the activation strain model

(2020) Pascal Vermeeren et al.   Nature Protocols

Organocatalytic asymmetric N-sulfonyl amide C-N bond activation to access axially chiral biaryl amino acids

(2020) Guanjie Wang et al.   Nature Communications

Bifunctional N-Heterocyclic Carbenes Derived from l-Pyroglutamic Acid and Their Applications in Enantioselective Organocatalysis

(2020) Xiang-Yu Chen et al.   ACCOUNTS OF CHEMICAL RESEARCH

N ‐Heterocyclic carbene organocatalysis: activation modes and typical reactive intermediates

(2020) Xingkuan Chen et al.   CHINESE JOURNAL OF CHEMISTRY

N-Heterocyclic Carbene Catalysis Exploiting Oxidative Imine Umpolung for the Generation of Imidoyl Azoliums

(2020) Tamal Kanti Das et al.   JOURNAL OF ORGANIC CHEMISTRY

Atroposelective Ring Opening of Cyclic Diaryliodonium Salts with Bulky Anilines Controlled by a Chiral Cobalt(III) Anion

(2020) Zhenhua Gu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Reductive Amination/Ring-Closing Cascade: Direct Synthesis of Enantioenriched Biaryl-Bridged NH Lactams

(2020) Yao Zhang et al.   ORGANIC LETTERS

N-Heterocyclic Carbene-Based Catalysis Enabling Cross-Coupling Reactions

(2020) Hirohisa Ohmiya   ACS Catalysis

Enantioselective N-heterocyclic carbene catalysis exploiting imine umpolung

(2019) Jared E. M. Fernando et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene-Catalyzed Umpolung of Imines for the Enantioselective Synthesis of Dihydroquinoxalines

(2019) Tamal Kanti Das et al.   ACS Catalysis

Synthesis of Bridged Biaryl Atropisomers via Sequential Cu- and Pd-Catalyzed Asymmetric Ring Opening and Cyclization

(2019) Xiaoping Xue et al.   ORGANIC LETTERS

NHC-Catalyzed Atroposelective Acylation of Phenols: Access to Enantiopure NOBIN Analogs by Desymmetrization

(2019) Shenci Lu et al.   ORGANIC LETTERS

NHC-catalyzed atropoenantioselective synthesis of axially chiral biaryl amino alcohols via a cooperative strategy

(2019) Gongming Yang et al.   Nature Communications

Atroposelective Arene Formation by Carbene-Catalyzed Formal [4+2] Cycloaddition

(2019) Ke Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diastereo- and Atroposelective Synthesis of Bridged Biaryls Bearing an Eight-Membered Lactone through an Organocatalytic Cascade

(2019) Shenci Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Construction of Axially Chiral Compounds via Asymmetric Organocatalysis

(2018) Yong-Bin Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

A continuing challenge: N-heterocyclic carbene-catalyzed syntheses of γ-butyrolactones

(2018) Kathleen J. R. Murauski et al.   CHEMICAL SOCIETY REVIEWS

Carbene-catalyzed aerobic oxidation of isoquinolinium salts: efficient synthesis of isoquinolinones

(2018) Guanjie Wang et al.   GREEN CHEMISTRY

Design and Synthesis of Chiral oxa-Spirocyclic Ligands for Ir-Catalyzed Direct Asymmetric Reduction of Bringmann’s Lactones with Molecular H2

(2018) Gen-Qiang Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of 4-Difluoromethylquinolines by NHC-Catalyzed Umpolung of Imines

(2018) Atanu Patra et al.   ORGANIC LETTERS

Enantioselective [3+3] atroposelective annulation catalyzed by N-heterocyclic carbenes

(2018) Changgui Zhao et al.   Nature Communications

Enhanced Reactivity by Torsional Strain of Cyclic Diaryliodonium in Cu-Catalyzed Enantioselective Ring-Opening Reaction

(2018) Kun Zhao et al.   Chem

Enantioselective N-Heterocyclic Carbene-Catalyzed Kinetic Resolution of Anilides

(2018) Jianbo Bie et al.   ORGANIC LETTERS

Oxidative NHC Catalysis for the Generation of Imidoyl Azoliums: Synthesis of Benzoxazoles

(2018) Atanu Patra et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Enantioselective Tautomerization of Metastable Enamines

(2017) Jingjing Liu et al.   ORGANIC LETTERS

Access to Amide from Aldimine via Aerobic Oxidative Carbene Catalysis and LiCl as Cooperative Lewis Acid

(2017) Guanjie Wang et al.   ORGANIC LETTERS

Cooperative Catalysis and Activation with N-Heterocyclic Carbenes

(2016) Michael H. Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonbiaryl and Heterobiaryl Atropisomers: Molecular Templates with Promise for Atropselective Chemical Transformations

(2015) Elango Kumarasamy et al.   CHEMICAL REVIEWS

N-Heterocyclic carbene catalysed redox isomerisation of esters to functionalised benzaldehydes

(2015) Lisa Candish et al.   Chemical Science

The activation strain model and molecular orbital theory

(2015) Lando P. Wolters et al.   Wiley Interdisciplinary Reviews-Computational Molecular Science

On the Mechanism of N-Heterocyclic Carbene-Catalyzed Reactions Involving Acyl Azoliums

(2014) Jessada Mahatthananchai et al.   ACCOUNTS OF CHEMICAL RESEARCH

Asymmetric Catalysis on the Nanoscale: The Organocatalytic Approach to Helicenes

(2014) Lisa Kötzner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Kinetic Resolution of 1,1′-Biaryl-2,2′-Diols and Amino Alcohols through NHC-Catalyzed Atroposelective Acylation

(2014) Shenci Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates

(2014) Dixit Parmar et al.   CHEMICAL REVIEWS

The activation strain model and molecular orbital theory: understanding and designing chemical reactions

(2014) Israel Fernández et al.   CHEMICAL SOCIETY REVIEWS

Enantioselective Synthesis and Enhanced Circularly Polarized Luminescence of S-Shaped Double Azahelicenes

(2014) Kyosuke Nakamura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An overview of N-heterocyclic carbenes

(2014) Matthew N. Hopkinson et al.   NATURE

Enantioselective Sulfonation of Enones with Sulfonyl Imines by Cooperative N-Heterocyclic-Carbene/Thiourea/Tertiary-Amine Multicatalysis

(2013) Zhichao Jin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Acyl anion free N-heterocyclic carbene organocatalysis

(2013) Sarah J. Ryan et al.   CHEMICAL SOCIETY REVIEWS

A photoisomerization-coupled asymmetric Stetter reaction: application to the total synthesis of three diastereomers of (−)-cephalimysin A

(2013) Stephen P. Lathrop et al.   Chemical Science

A Continuum of Progress: Applications of N-Hetereocyclic Carbene Catalysis in Total Synthesis

(2012) Javier Izquierdo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic umpolung: N-heterocyclic carbenes and beyond

(2012) Xavier Bugaut et al.   CHEMICAL SOCIETY REVIEWS

Isolable Analogues of the Breslow Intermediate Derived from Chiral Triazolylidene Carbenes

(2012) Daniel A. DiRocco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Extending NHC-Catalysis: Coupling Aldehydes with Unconventional Reaction Partners

(2011) Akkattu T. Biju et al.   ACCOUNTS OF CHEMICAL RESEARCH

Employing homoenolates generated by NHC catalysis in carbon–carbon bond-forming reactions: state of the art

(2011) Vijay Nair et al.   CHEMICAL SOCIETY REVIEWS

Efficient Organocatalytic Cross-Aldol Reaction between Aliphatic Aldehydes through Their Functional Differentiation

(2011) Taichi Kano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cooperative Lewis acid/N-heterocyclic carbene catalysis

(2011) Daniel T. Cohen et al.   Chemical Science

NHC Catalyzed Oxidations of Aldehydes to Esters: Chemoselective Acylation of Alcohols in Presence of Amines

(2010) Suman De Sarkar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Route to 5-Methyl- and 5,7-Dimethyl-6,7-dihydro-5H-dibenz[c,e]azepine: Secondary Amines with Switchable Axial Chirality

(2009) Silvain L. Pira et al.   ORGANIC LETTERS

Addition of N-Heterocyclic Carbenes to Imines: Phenoxide Assisted Deprotonation of an Imidazolium Moiety and Generation of Breslow Intermediates Derived from Imines

(2008) Stevan Simonovic et al.   ORGANIC LETTERS