Production of MHCII ‐expressing classical monocytes increases during aging in mice and humans

Effects of sex and aging on the immune cell landscape as assessed by single-cell transcriptomic analysis

(2021) Zhaohao Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aged healthy mice acquire clonal hematopoiesis mutations

(2021) Desmond Wai Loon Chin et al.   BLOOD

Monocytes present age‐related changes in phospholipid concentration and decreased energy metabolism

(2020) Mario Saare et al.   AGING CELL

Lineage tracing on transcriptional landscapes links state to fate during differentiation

(2020) Caleb Weinreb et al.   SCIENCE

Long Noncoding RNA AW112010 Promotes the Differentiation of Inflammatory T Cells by Suppressing IL-10 Expression through Histone Demethylation

(2020) Xiaoming Yang et al.   JOURNAL OF IMMUNOLOGY

Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging

(2019) Ya-Hsuan Ho et al.   Cell Stem Cell

The Ontogeny of Monocyte Subsets

(2019) Anja A. Wolf et al.   Frontiers in Immunology

Immunosenescence and Its Hallmarks: How to Oppose Aging Strategically? A Review of Potential Options for Therapeutic Intervention

(2019) Anna Aiello et al.   Frontiers in Immunology

Aging promotes reorganization of the CD4 T cell landscape toward extreme regulatory and effector phenotypes

(2019) Yehezqel Elyahu et al.   Science Advances

Single-Cell Chromatin Modification Profiling Reveals Increased Epigenetic Variations with Aging

(2018) Peggie Cheung et al.   CELL

Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction

(2018) Netusha Thevaranjan et al.   Cell Host & Microbe

Aging impairs mitochondrial respiratory capacity in classical monocytes

(2018) Brandt D. Pence et al.   EXPERIMENTAL GERONTOLOGY

Population snapshots predict early haematopoietic and erythroid hierarchies

(2018) Betsabeh Khoramian Tusi et al.   NATURE

Developmental and Functional Heterogeneity of Monocytes

(2018) Martin Guilliams et al.   IMMUNITY

Granulocyte-Monocyte Progenitors and Monocyte-Dendritic Cell Progenitors Independently Produce Functionally Distinct Monocytes

(2017) Alberto Yáñez et al.   IMMUNITY

Human Monocyte Subsets Are Transcriptionally and Functionally Altered in Aging in Response to Pattern Recognition Receptor Agonists

(2017) Talibah U. Metcalf et al.   JOURNAL OF IMMUNOLOGY

Aging Impairs Alveolar Macrophage Phagocytosis and Increases Influenza-Induced Mortality in Mice

(2017) Christine K. Wong et al.   JOURNAL OF IMMUNOLOGY

Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells

(2016) Amit Grover et al.   Nature Communications

TNF Drives Monocyte Dysfunction with Age and Results in Impaired Anti-pneumococcal Immunity

(2016) Alicja Puchta et al.   PLoS Pathogens

Age-related variations in the methylome associated with gene expression in human monocytes and T cells

(2014) Lindsay M. Reynolds et al.   Nature Communications

Nr4a1-Dependent Ly6Clow Monocytes Monitor Endothelial Cells and Orchestrate Their Disposal

(2013) Leo M. Carlin et al.   CELL

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells

(2011) Brad Dykstra et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

(2011) Saul A. Villeda et al.   NATURE