Monocytes present age‐related changes in phospholipid concentration and decreased energy metabolism

The Myeloid Cell Compartment—Cell by Cell

(2019) Kevin Bassler et al.   Annual Review of Immunology

Aging impairs mitochondrial respiratory capacity in classical monocytes

(2018) Brandt D. Pence et al.   EXPERIMENTAL GERONTOLOGY

Epigenetics of T cell aging

(2018) Jörg J. Goronzy et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human Monocyte Heterogeneity as Revealed by High-Dimensional Mass Cytometry

(2018) Anouk A.J. Hamers et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Developmental and Functional Heterogeneity of Monocytes

(2018) Martin Guilliams et al.   IMMUNITY

Non-linear patterns in age-related DNA methylation may reflect CD4+ T cell differentiation

(2017) Nicholas D. Johnson et al.   Epigenetics

Monocyte-Macrophages and T Cells in Atherosclerosis

(2017) Ira Tabas et al.   IMMUNITY

Enhancement of cutaneous immunity during aging by blocking p38 mitogen-activated protein (MAP) kinase–induced inflammation

(2017) Milica Vukmanovic-Stejic et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The chromatin accessibility signature of human immune aging stems from CD8+T cells

(2017) Duygu Ucar et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human Monocyte Subsets Are Transcriptionally and Functionally Altered in Aging in Response to Pattern Recognition Receptor Agonists

(2017) Talibah U. Metcalf et al.   JOURNAL OF IMMUNOLOGY

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

(2017) Alexandra-Chloé Villani et al.   SCIENCE

Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis

(2017) Yongmei Liu et al.   Nature Communications

Metabolism Supports Macrophage Activation

(2017) P. Kent Langston et al.   Frontiers in Immunology

Advanced Age Alters Monocyte and Macrophage Responses

(2016) Joslyn M. Albright et al.   ANTIOXIDANTS & REDOX SIGNALING

Innate immune cell activation and epigenetic remodeling in symptomatic and asymptomatic atherosclerosis in humans in vivo

(2016) Siroon Bekkering et al.   ATHEROSCLEROSIS

Inflammation increases pyruvate dehydrogenase kinase 4 (PDK4) expression via the Jun N-Terminal Kinase (JNK) pathway in C2C12 cells

(2016) Hana Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Macrophages in Tissue Repair, Regeneration, and Fibrosis

(2016) Thomas A. Wynn et al.   IMMUNITY

ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases

(2016) Pierpaola Davalli et al.   Oxidative Medicine and Cellular Longevity

A RhoA and Rnd3 cycle regulates actin reassembly during membrane blebbing

(2016) Kana Aoki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease

(2016) P. S. Pillai et al.   SCIENCE

The role of the ribosome in the regulation of longevity and lifespan extension

(2016) Alyson W. MacInnes   Wiley Interdisciplinary Reviews-RNA

Defective Signaling in the JAK-STAT Pathway Tracks with Chronic Inflammation and Cardiovascular Risk in Aging Humans

(2016) Shai S. Shen-Orr et al.   Cell Systems

How sex and age affect immune responses, susceptibility to infections, and response to vaccination

(2015) Carmen Giefing-Kröll et al.   AGING CELL

Transcriptomic profiles of aging in purified human immune cells

(2015) Lindsay M Reynolds et al.   BMC GENOMICS

Peroxisome proliferator-activated receptor (PPAR) gamma in cardiovascular disorders and cardiovascular surgery

(2015) Ekaterina A. Ivanova et al.   Journal of Cardiology

The transcriptional landscape of age in human peripheral blood

(2015) Marjolein J. Peters et al.   Nature Communications

Age-related profiling of DNA methylation in CD8+ T cells reveals changes in immune response and transcriptional regulator genes

(2015) Liina Tserel et al.   Scientific Reports

Mitohormesis

(2014) Jeanho Yun et al.   Cell Metabolism

mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity

(2014) S.-C. Cheng et al.   SCIENCE

mTORC1 signaling controls multiple steps in ribosome biogenesis

(2014) Valentina Iadevaia et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Age-related variations in the methylome associated with gene expression in human monocytes and T cells

(2014) Lindsay M. Reynolds et al.   Nature Communications

Meta-analysis on blood transcriptomic studies identifies consistently coexpressed protein-protein interaction modules as robust markers of human aging

(2013) Erik B. van den Akker et al.   AGING CELL

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Methylomics of gene expression in human monocytes

(2013) Yongmei Liu et al.   HUMAN MOLECULAR GENETICS

The role of mitochondria in aging

(2013) Ana Bratic et al.   JOURNAL OF CLINICAL INVESTIGATION

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

Methylation ofELOVL2gene as a new epigenetic marker of age

(2012) Paolo Garagnani et al.   AGING CELL

Human serum metabolic profiles are age dependent

(2012) Zhonghao Yu et al.   AGING CELL

Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects

(2012) Kristel R van Eijk et al.   BMC GENOMICS

Ly6Chi Monocytes in the Inflamed Colon Give Rise to Proinflammatory Effector Cells and Migratory Antigen-Presenting Cells

(2012) Ehud Zigmond et al.   IMMUNITY

Age-associated changes in gene expression in human brain and isolated neurons

(2012) Azad Kumar et al.   NEUROBIOLOGY OF AGING

Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks

(2011) Brian Magnuson et al.   BIOCHEMICAL JOURNAL

Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control

(2011) Robbie Loewith et al.   GENETICS

Control of Macrophage Activation and Function by PPARs

(2010) Ajay Chawla   CIRCULATION RESEARCH

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

(2010) Shomit Sengupta et al.   MOLECULAR CELL

CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival

(2008) L. Landsman et al.   BLOOD

The immune system in extreme longevity

(2007) P. Sansoni et al.   EXPERIMENTAL GERONTOLOGY

Modulator Recognition Factor-2 Is Required for Adipogenesis in Mouse Embryo Fibroblasts and 3T3-L1 Cells

(2007) Takahiro Yamakawa et al.   MOLECULAR ENDOCRINOLOGY