High-dimensional single-cell analysis reveals the immune signature of narcolepsy

Vaccine-associated inflammatory diseases of the central nervous system

(2016) Xuan-Hung Nguyen et al.   CURRENT OPINION IN NEUROLOGY

Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour

(2016) Anthony J. Filiano et al.   NATURE

The cellular composition of the human immune system is shaped by age and cohabitation

(2016) Edward J Carr et al.   NATURE IMMUNOLOGY

Autoantibody-boosted T-cell reactivation in the target organ triggers manifestation of autoimmune CNS disease

(2016) Anne-Christine Flach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection, phenotyping, and quantification of antigen-specific T cells using a peptide-MHC dodecamer

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CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice

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Narcolepsy-Associated HLA Class I Alleles Implicate Cell-Mediated Cytotoxicity

(2016) Mehdi Tafti et al.   SLEEP

Narcolepsy-Associated HLA Class I Alleles Implicate Cell-Mediated Cytotoxicity

(2016) Mehdi Tafti et al.   SLEEP

HLA-DPB1 and HLA Class I Confer Risk of and Protection from Narcolepsy

(2015) Hanna M. Ollila et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Effect of long-term sleep restriction and subsequent recovery sleep on the diurnal rhythms of white blood cell subpopulations

(2015) Julie Lasselin et al.   BRAIN BEHAVIOR AND IMMUNITY

Cerebrospinal fluid cytokine levels in type 1 narcolepsy patients very close to onset

(2015) Birgitte Rahbek Kornum et al.   BRAIN BEHAVIOR AND IMMUNITY

Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis

(2015) Jacob H. Levine et al.   CELL

FlowSOM: Using self-organizing maps for visualization and interpretation of cytometry data

(2015) Sofie Van Gassen et al.   CYTOMETRY PART A

Neurons and T cells: Understanding this interaction for inflammatory neurological diseases

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The end of gating? An introduction to automated analysis of high dimensional cytometry data

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Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8+ T Lymphocytes

(2015) Wong Yu et al.   IMMUNITY

Autoantibodies against ganglioside GM3 are associated with narcolepsy-cataplexy developing after Pandemrix vaccination against 2009 pandemic H1N1 type influenza virus

(2015) Anna-Helena Saariaho et al.   JOURNAL OF AUTOIMMUNITY

Barcoding of Live Human Peripheral Blood Mononuclear Cells for Multiplexed Mass Cytometry

(2015) Henrik E. Mei et al.   JOURNAL OF IMMUNOLOGY

Innate and adaptive immune responses in the CNS

(2015) Ari Waisman et al.   LANCET NEUROLOGY

Hypocretin (orexin) biology and the pathophysiology of narcolepsy with cataplexy

(2015) Roland S Liblau et al.   LANCET NEUROLOGY

T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection

(2015) Eoin F. McKinney et al.   NATURE

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

Rapid linkage of innate immunological signals to adaptive immunity by the brain-fat axis

(2015) Min Soo Kim et al.   NATURE IMMUNOLOGY

Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm

(2015) Eli R Zunder et al.   Nature Protocols

Narcolepsy

(2015) Thomas E. Scammell   NEW ENGLAND JOURNAL OF MEDICINE

An interactive reference framework for modeling a dynamic immune system

(2015) M. H. Spitzer et al.   SCIENCE

Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2

(2015) Syed Sohail Ahmed et al.   Science Translational Medicine

Mass Cytometric Functional Profiling of Acute Myeloid Leukemia Defines Cell-Cycle and Immunophenotypic Properties That Correlate with Known Responses to Therapy

(2015) G. K. Behbehani et al.   Cancer Discovery

Cerebrospinal fluid and serum cytokine profiles in narcolepsy with cataplexy: A case-control study

(2014) Yves Dauvilliers et al.   BRAIN BEHAVIOR AND IMMUNITY

Increased plasma IL-6, IL-8, TNF-alpha, and G-CSF in Japanese narcolepsy

(2014) Susumu Tanaka et al.   HUMAN IMMUNOLOGY

Narcolepsy patients have antibodies that stain distinct cell populations in rat brain and influence sleep patterns

(2014) P. Bergman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical recovery from surgery correlates with single-cell immune signatures

(2014) B. Gaudilliere et al.   Science Translational Medicine

DQB1 Locus Alone Explains Most of the Risk and Protection in Narcolepsy with Cataplexy in Europe

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Normalization of mass cytometry data with bead standards

(2013) Rachel Finck et al.   CYTOMETRY PART A

viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia

(2013) El-ad David Amir et al.   NATURE BIOTECHNOLOGY

Partial Sleep Restriction Activates Immune Response-Related Gene Expression Pathways: Experimental and Epidemiological Studies in Humans

(2013) Vilma Aho et al.   PLoS One

Childhood narcolepsy with cataplexy: comparison between post-H1N1 vaccination and sporadic cases

(2013) Fabio Pizza et al.   SLEEP MEDICINE

Genome Wide Analysis of Narcolepsy in China Implicates Novel Immune Loci and Reveals Changes in Association Prior to Versus After the 2009 H1N1 Influenza Pandemic

(2013) Fang Han et al.   PLoS Genetics

A platinum-based covalent viability reagent for single-cell mass cytometry

(2012) Harris G. Fienberg et al.   CYTOMETRY PART A

Hiding under the skin: Interleukin-17–producing γδ T cells go under the skin?

(2012) Burkhard Becher et al.   NATURE MEDICINE

B cells and antibodies in multiple sclerosis pathogenesis and therapy

(2012) Markus Krumbholz et al.   Nature Reviews Neurology

Diurnal Rhythms in Blood Cell Populations and the Effect of Acute Sleep Deprivation in Healthy Young Men

(2012) Katrin Ackermann et al.   SLEEP

A deep profiler's guide to cytometry

(2012) Sean C. Bendall et al.   TRENDS IN IMMUNOLOGY

Multiobjective evolutionary algorithms to identify highly autocorrelated areas: the case of spatial distribution in financially compromised farms

(2011) Carlos R. García-Alonso et al.   ANNALS OF OPERATIONS RESEARCH

Psoriasis

(2011) Gayathri K. Perera et al.   Annual Review of Pathology-Mechanisms of Disease

Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum

(2011) S. C. Bendall et al.   SCIENCE

Elevated Tribbles homolog 2–specific antibody levels in narcolepsy patients

(2010) Vesna Cvetkovic-Lopes et al.   JOURNAL OF CLINICAL INVESTIGATION

How does multiple testing correction work?

(2009) William S Noble   NATURE BIOTECHNOLOGY

Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells

(2009) Marion Pepper et al.   NATURE IMMUNOLOGY

Feeding Our Immune System: Impact on Metabolism

(2008) Isabelle Wolowczuk et al.   Clinical & Developmental Immunology