Rapid linkage of innate immunological signals to adaptive immunity by the brain-fat axis

Obesity- and aging-induced excess of central transforming growth factor-β potentiates diabetic development via an RNA stress response

(2014) Jingqi Yan et al.   NATURE MEDICINE

Chinese agriculture: An experiment for the world

(2013) Fusuo Zhang et al.   NATURE

Hunger-promoting hypothalamic neurons modulate effector and regulatory T-cell responses

(2013) G. Matarese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peripheral elevation of TNF-  leads to early synaptic abnormalities in the mouse somatosensory cortex in experimental autoimmune encephalomyelitis

(2013) G. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immune-neural connections: how the immune system's response to infectious agents influences behavior

(2012) R. H. McCusker et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

IKKβ/NF-κB disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes

(2012) Juxue Li et al.   NATURE CELL BIOLOGY

Neurodegenerative disease and adult neurogenesis

(2011) Beate Winner et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Defective Hypothalamic Autophagy Directs the Central Pathogenesis of Obesity via the IκB Kinase β (IKKβ)/NF-κB Pathway

(2011) Qingyuan Meng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Obesity is associated with hypothalamic injury in rodents and humans

(2011) Joshua P. Thaler et al.   JOURNAL OF CLINICAL INVESTIGATION

Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NF-κB

(2011) Sudarshana Purkayastha et al.   NATURE MEDICINE

Neural dysregulation of peripheral insulin action and blood pressure by brain endoplasmic reticulum stress

(2011) S. Purkayastha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal GPCR Controls Innate Immunity by Regulating Noncanonical Unfolded Protein Response Genes

(2011) J. Sun et al.   SCIENCE

Toll-like receptors: linking inflammation to metabolism

(2010) A. Christine Könner et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Hematopoietic Cell-Specific Deletion of Toll-like Receptor 4 Ameliorates Hepatic and Adipose Tissue Insulin Resistance in High-Fat-Fed Mice

(2009) Maziyar Saberi et al.   Cell Metabolism

Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome

(2009) Michael B Fessler et al.   CURRENT OPINION IN LIPIDOLOGY

Bacterial Endotoxin Stimulates Adipose Lipolysis via Toll-Like Receptor 4 and Extracellular Signal-regulated Kinase Pathway

(2009) Luxia Zu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

(2009) Erika L. Pearce et al.   NATURE

Human P-selectin glycoprotein ligand-1 is a functional receptor for enterovirus 71

(2009) Yorihiro Nishimura et al.   NATURE MEDICINE

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet

(2008) Kelly A. Posey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

(2008) Xiaoqing Zhang et al.   CELL

Leptin Acts in the Periphery to Protect Thymocytes from Glucocorticoid-Mediated Apoptosis in the Absence of Weight Loss

(2008) Robert N. Trotter-Mayo et al.   ENDOCRINOLOGY

Leptin controls adipose tissue lipogenesis via central, STAT3–independent mechanisms

(2008) Christoph Buettner et al.   NATURE MEDICINE

Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia

(2008) M. Rosas-Ballina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA