Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1

SLAM family receptors in normal immunity and immune pathologies

(2016) Ning Wu et al.   CURRENT OPINION IN IMMUNOLOGY

A hematopoietic cell–driven mechanism involving SLAMF6 receptor, SAP adaptors and SHP-1 phosphatase regulates NK cell education

(2016) Ning Wu et al.   NATURE IMMUNOLOGY

Roles of natural killer cells in antiviral immunity

(2016) Stephen N Waggoner et al.   Current Opinion in Virology

XLP: Clinical Features and Molecular Etiology due to Mutations in SH2D1A Encoding SAP

(2014) Stuart G Tangye   JOURNAL OF CLINICAL IMMUNOLOGY

EAT-2, a SAP-like adaptor, controls NK cell activation through phospholipase Cγ, Ca++, and Erk, leading to granule polarization

(2014) Luis-Alberto Pérez-Quintero et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A signaling network stimulated by  2 integrin promotes the polarization of lytic granules in cytotoxic cells

(2014) M. Zhang et al.   Science Signaling

X-linked lymphoproliferative syndromes and related autosomal recessive disorders

(2013) André Veillette et al.   Current Opinion in Allergy and Clinical Immunology

Macrophage Fusion Is Controlled by the Cytoplasmic Protein Tyrosine Phosphatase PTP-PEST/PTPN12

(2013) I. Rhee et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of Mouse NK Cell Development and Function by Cytokines

(2013) Antoine Marçais et al.   Frontiers in Immunology

Tuning the threshold of natural killer cell responses

(2012) Emilie Narni-Mancinelli et al.   CURRENT OPINION IN IMMUNOLOGY

The Adaptor SAP Controls NK Cell Activation by Regulating the Enzymes Vav-1 and SHIP-1 and by Enhancing Conjugates with Target Cells

(2012) Zhongjun Dong et al.   IMMUNITY

Positive and Negative Signaling through SLAM Receptors Regulate Synapse Organization and Thresholds of Cytolysis

(2012) Fang Zhao et al.   IMMUNITY

The Receptor Ly108 Functions as a SAP Adaptor-Dependent On-Off Switch for T Cell Help to B Cells and NKT Cell Development

(2012) Robin Kageyama et al.   IMMUNITY

Evolving role of 2B4/CD244 in T and NK cell responses during virus infection

(2012) Stephen N. Waggoner et al.   Frontiers in Immunology

SLAM Family Receptors and SAP Adaptors in Immunity

(2011) Jennifer L. Cannons et al.   Annual Review of Immunology

Cutting Edge: A Dual Role for Type I IFNs during Polyinosinic-Polycytidylic Acid-Induced NK Cell Activation

(2011) H. Beuneu et al.   JOURNAL OF IMMUNOLOGY

Natural killer cells act as rheostats modulating antiviral T cells

(2011) Stephen N. Waggoner et al.   NATURE

Unifying concepts of MHC-dependent natural killer cell education

(2011) Julie M. Elliott et al.   TRENDS IN IMMUNOLOGY

Natural Killer Cell Education and Tolerance

(2010) Mark T. Orr et al.   CELL

Absence of mouse 2B4 promotes NK cell–mediated killing of activated CD8+ T cells, leading to prolonged viral persistence and altered pathogenesis

(2010) Stephen N. Waggoner et al.   JOURNAL OF CLINICAL INVESTIGATION

Tethering of Intercellular Adhesion Molecule on Target Cells Is Required for LFA-1-Dependent NK Cell Adhesion and Granule Polarization

(2010) C. C. Gross et al.   JOURNAL OF IMMUNOLOGY

SLAM-Family Receptors: Immune Regulators with or without SAP-Family Adaptors

(2010) A. Veillette   Cold Spring Harbor Perspectives in Biology

Essential function for SAP family adaptors in the surveillance of hematopoietic cells by natural killer cells

(2009) Zhongjun Dong et al.   NATURE IMMUNOLOGY

Cytokine-induced memory-like natural killer cells

(2009) Megan A. Cooper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NKG2D-Deficient Mice Are Defective in Tumor Surveillance in Models of Spontaneous Malignancy

(2008) Nadia Guerra et al.   IMMUNITY

DNAM-1 promotes activation of cytotoxic lymphocytes by nonprofessional antigen-presenting cells and tumors

(2008) Susan Gilfillan et al.   JOURNAL OF EXPERIMENTAL MEDICINE