A Fast and Robust Strategy to Remove Variant-Level Artifacts in Alzheimer Disease Sequencing Project Data

Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer’s disease

(2021) Liang He et al.   Translational Psychiatry

Whole‐genome sequencing reveals new Alzheimer's disease–associated rare variants in loci related to synaptic function and neuronal development

(2021) Dmitry Prokopenko et al.   Alzheimers & Dementia

Impact of variant-level batch effects on identification of genetic risk factors in large sequencing studies

(2021) Daniel P. Wickland et al.   PLoS One

A novel age-informed approach for genetic association analysis in Alzheimer’s disease

(2021) Yann Le Guen et al.   Alzheimers Research & Therapy

Novel Alzheimer’s disease risk variants identified based on whole-genome sequencing of APOE ε4 carriers

(2021) Jong-Ho Park et al.   Translational Psychiatry

Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores

(2021) Itziar de Rojas et al.   Nature Communications

Identification of putative causal loci in whole-genome sequencing data via knockoff statistics

(2021) Zihuai He et al.   Nature Communications

Interpretation of risk loci from genome-wide association studies of Alzheimer's disease

(2020) Shea J Andrews et al.   LANCET NEUROLOGY

The multiplex model of the genetics of Alzheimer’s disease

(2020) Rebecca Sims et al.   NATURE NEUROSCIENCE

The mutational constraint spectrum quantified from variation in 141,456 humans

(2020) Konrad J. Karczewski et al.   NATURE

Non‐coding variants in MYH11 , FZD3 , and SORCS3 are associated with dementia in women

(2020) Elizabeth E. Blue et al.   Alzheimers & Dementia

The Role of Age-Related Clonal Hematopoiesis in Genetic Sequencing Studies

(2020) Henne Holstege et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Translating genetic risk of Alzheimer’s disease into mechanistic insight and drug targets

(2020) Annerieke Sierksma et al.   SCIENCE

Cauchy combination test: a powerful test with analytic p-value calculation under arbitrary dependency structures

(2019) Yaowu Liu et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

(2019) Iris E. Jansen et al.   NATURE GENETICS

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

(2019) Brian W. Kunkle et al.   NATURE GENETICS

Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype

(2019) Yiyi Ma et al.   JAMA Neurology

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

(2018) Joshua C. Bis et al.   MOLECULAR PSYCHIATRY

VCPA: genomic variant calling pipeline and data management tool for Alzheimer’s Disease Sequencing Project

(2018) Yuk Yee Leung et al.   BIOINFORMATICS

Allele balance bias identifies systematic genotyping errors and false disease associations

(2018) Francesc Muyas et al.   HUMAN MUTATION

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Robust Inference of Population Structure for Ancestry Prediction and Correction of Stratification in the Presence of Relatedness

(2015) Matthew P. Conomos et al.   GENETIC EPIDEMIOLOGY

Contactin-4 Mediates Axon-Target Specificity and Functional Development of the Accessory Optic System

(2015) Jessica A. Osterhout et al.   NEURON

Effective filtering strategies to improve data quality from population-based whole exome sequencing studies

(2014) Andrew R Carson et al.   BMC BIOINFORMATICS

Improved ancestry inference using weights from external reference panels

(2013) Chia-Yen Chen et al.   BIOINFORMATICS

Simultaneous Genotype Calling and Haplotype Phasing Improves Genotype Accuracy and Reduces False-Positive Associations for Genome-wide Association Studies

(2009) Brian L. Browning et al.   AMERICAN JOURNAL OF HUMAN GENETICS