MicroRNA-224 sustains Wnt/β-catenin signaling and promotes aggressive phenotype of colorectal cancer

Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer

(2015) Lukas E. Dow et al.   CELL

The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis

(2015) Hui Ling et al.   GUT

Early detection of colorectal cancer: from conventional methods to novel biomarkers

(2015) Nasimeh Vatandoost et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

MicroRNA-106b promotes colorectal cancer cell migration and invasion by directly targeting DLC1

(2015) Guang-jun Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Plasma levels of microRNA-24, microRNA-320a, and microRNA-423-5p are potential biomarkers for colorectal carcinoma

(2015) Zanxi Fang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Reduction of miR-29c enhances pancreatic cancer cell migration and stem cell-like phenotype

(2015) Jianxin Jiang et al.   Oncotarget

A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling by driving a catalytic cycle of efficient βcatenin destruction

(2015) Mira I Pronobis et al.   eLife

Regulation of Colorectal Carcinoma Stemness, Growth, and Metastasis by an miR-200c-Sox2-Negative Feedback Loop Mechanism

(2014) Y.-X. Lu et al.   CLINICAL CANCER RESEARCH

MicroRNA-301a promotes migration and invasion by targeting TGFBR2 in human colorectal cancer

(2014) Wenpeng Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Wnt3a expression is associated with epithelial-mesenchymal transition and promotes colon cancer progression

(2014) Lisha Qi et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells

(2014) Wei-Lun Hwang et al.   NATURE CELL BIOLOGY

Tissue-specific derepression of TCF/LEF controls the activity of the Wnt/β-catenin pathway

(2014) Fu-I Lu et al.   Nature Communications

MicroRNAs - A New Generation Molecular Targets for Treating Cellular Diseases

(2014) Ramasamy Paulmurugan   Theranostics

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Tumor-suppressive microRNA-145 targets catenin δ-1 to regulate Wnt/β-catenin signaling in human colon cancer cells

(2013) Nami Yamada et al.   CANCER LETTERS

MicroRNA-Antagonism Regulates Breast Cancer Stemness and Metastasis via TET-Family-Dependent Chromatin Remodeling

(2013) Su Jung Song et al.   CELL

Inhibition of GSK3B Bypass Drug Resistance of p53-Null Colon Carcinomas by Enabling Necroptosis in Response to Chemotherapy

(2013) E. Grassilli et al.   CLINICAL CANCER RESEARCH

microRNA-224 Promotes Cell Proliferation and Tumor Growth in Human Colorectal Cancer by Repressing PHLPP1 and PHLPP2

(2013) W.-T. Liao et al.   CLINICAL CANCER RESEARCH

XAV939, a tankyrase 1 inhibitior, promotes cell apoptosis in neuroblastoma cell lines by inhibiting Wnt/β-catenin signaling pathway

(2013) Xiao-Hong Tian et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

MicroRNA-30b functions as a tumour suppressor in human colorectal cancer by targetingKRAS,PIK3CDandBCL2

(2013) Wen-Ting Liao et al.   JOURNAL OF PATHOLOGY

MicroRNA-224 targets RKIP to control cell invasion and expression of metastasis genes in human breast cancer cells

(2012) Lin Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNA-224 is up-regulated in hepatocellular carcinoma through epigenetic mechanisms

(2012) Yu Wang et al.   FASEB JOURNAL

miR-574-5p negatively regulatesQki6/7to impactβ-catenin/Wnt signalling and the development of colorectal cancer

(2012) Shunlong Ji et al.   GUT

HOXB7 as a Prognostic Factor and Mediator of Colorectal Cancer Progression

(2011) W.-T. Liao et al.   CLINICAL CANCER RESEARCH

Coordinated Action of CK1 Isoforms in Canonical Wnt Signaling

(2011) B. del Valle-Perez et al.   MOLECULAR AND CELLULAR BIOLOGY

β-Catenin/LEF1 transactivates the microRNA-371-373 cluster that modulates the Wnt/β-catenin-signaling pathway

(2011) A-D Zhou et al.   ONCOGENE

Wnt Signaling Requires Sequestration of Glycogen Synthase Kinase 3 inside Multivesicular Endosomes

(2010) Vincent F. Taelman et al.   CELL

A Two-Step Model for Colon Adenoma Initiation and Progression Caused by APC Loss

(2009) Reid A. Phelps et al.   CELL

WIF1, a Wnt pathway inhibitor, regulates SKP2 and c-myc expression leading to G1 arrest and growth inhibition of human invasive urinary bladder cancer cells

(2009) Y. Tang et al.   MOLECULAR CANCER THERAPEUTICS

SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway

(2008) Ming-Tzeung Chung et al.   GYNECOLOGIC ONCOLOGY

Profiling MicroRNA Expression in Hepatocellular Carcinoma Reveals MicroRNA-224 Up-regulation and Apoptosis Inhibitor-5 as a MicroRNA-224-specific Target

(2008) Yu Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

APC Is Essential for Targeting Phosphorylated β-Catenin to the SCFβ-TrCP Ubiquitin Ligase

(2008) YunYun Su et al.   MOLECULAR CELL

B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver

(2008) K. R. Reed et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA