Non-Native Amino Acid Click Chemistry-Based Technology for Site-Specific Polysaccharide Conjugation to a Bacterial Protein Serving as Both Carrier and Vaccine Antigen

Immunogenicity Assessment of Cell Wall Carbohydrates of Group A Streptococcus via Self-Adjuvanted Glyco-lipopeptides

(2021) Farjana Khatun et al.   ACS Infectious Diseases

Recent advances on smart glycoconjugate vaccines in infections and cancer

(2021) Marko Anderluh et al.   FEBS Journal

Non-clinical immunological comparison of a Next-Generation 24-valent pneumococcal conjugate vaccine (VAX-24) using site-specific carrier protein conjugation to the current standard of care (PCV13 and PPV23)

(2021) Jeff Fairman et al.   VACCINE

Streptolysins are the primary inflammasome activators in macrophages during Streptococcus pyogenes infection

(2021) Johanna Richter et al.   IMMUNOLOGY AND CELL BIOLOGY

Immunobiology of the Classical Lancefield Group A Streptococcal Carbohydrate Antigen

(2021) Nina J. Gao et al.   INFECTION AND IMMUNITY

Polysaccharide peptide conjugates: Chemistry, properties and applications

(2021) Tamilselvan Mohan et al.   CARBOHYDRATE POLYMERS

SLO and Steady: Role of Streptolysin O during Inflammasome Activation in Group A Streptococcus‐infected THP‐1 Macrophages

(2020) Cheldon Ann T. Alcantara et al.   FASEB JOURNAL

Vaccine-Induced Th1-Type Response Protects against Invasive Group A Streptococcus Infection in the Absence of Opsonizing Antibodies

(2020) Tania Rivera-Hernandez et al.   mBio

Gold nanoparticles morphology does not affect the multivalent presentation and antibody recognition of Group A Streptococcus synthetic oligorhamnans

(2020) Olimpia Pitirollo et al.   BIOORGANIC CHEMISTRY

An Experimental Group A Streptococcus Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model

(2019) Tania Rivera-Hernandez et al.   mBio

Group A Streptococcus Cell Wall Oligosaccharide-Streptococcal C5a Peptidase Conjugates as Effective Antibacterial Vaccines

(2019) Subo Wang et al.   ACS Infectious Diseases

Malaria Derived Glycosylphosphatidylinositol Anchor Enhances Anti-Pfs25 Functional Antibodies That Block Malaria Transmission

(2018) Neeraj Kapoor et al.   BIOCHEMISTRY

Diversity-Generating Machines: Genetics of Bacterial Sugar-Coating

(2018) Rafał J. Mostowy et al.   TRENDS IN MICROBIOLOGY

On the mechanisms of conjugate vaccines

(2018) Rino Rappuoli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Investigating the candidacy of the serotype specific rhamnan polysaccharide based glycoconjugates to prevent disease caused by the dental pathogen Streptococcus mutans

(2017) Frank St. Michael et al.   GLYCOCONJUGATE JOURNAL

A Red Blood Cell Membrane-Camouflaged Nanoparticle Counteracts Streptolysin O-Mediated Virulence Phenotypes of Invasive Group A Streptococcus

(2017) Tamara Escajadillo et al.   Frontiers in Pharmacology

Differing Efficacies of Lead Group A Streptococcal Vaccine Candidates and Full-Length M Protein in Cutaneous and Invasive Disease Models

(2016) Tania Rivera-Hernandez et al.   mBio

Anti-Group B Streptococcus Glycan-Conjugate Vaccines Using Pilus Protein GBS80 As Carrier and Antigen: Comparing Lysine and Tyrosine-directed Conjugation

(2015) Alberto Nilo et al.   ACS Chemical Biology

Exploring the Effect of Conjugation Site and Chemistry on the Immunogenicity of an anti-Group B Streptococcus Glycoconjugate Vaccine Based on GBS67 Pilus Protein and Type V Polysaccharide

(2015) Alberto Nilo et al.   BIOCONJUGATE CHEMISTRY

Interactions of conjugate vaccines and co-administered vaccines

(2015) H Findlow et al.   Human Vaccines & Immunotherapeutics

Streptolysin O Rapidly Impairs Neutrophil Oxidative Burst and Antibacterial Responses to Group A Streptococcus

(2015) Satoshi Uchiyama et al.   Frontiers in Immunology

Tyrosine-Directed Conjugation of Large Glycans to Proteins via Copper-Free Click Chemistry

(2014) Alberto Nilo et al.   BIOCONJUGATE CHEMISTRY

The Classical Lancefield Antigen of Group A Streptococcus Is a Virulence Determinant with Implications for Vaccine Design

(2014) Nina M. van Sorge et al.   Cell Host & Microbe

Targeted Amino Acid Substitutions Impair Streptolysin O Toxicity and Group A Streptococcus Virulence

(2013) E. Chiarot et al.   mBio

Protein carriers of conjugate vaccines: Characteristics, development and clinical trials

(2013) Michael E Pichichero   Human Vaccines & Immunotherapeutics

Reduction of Streptolysin O (SLO) Pore-Forming Activity Enhances Inflammasome Activation

(2013) Peter Keyel et al.   Toxins

Microscale to manufacturing scale-up of cell-free cytokine production-a new approach for shortening protein production development timelines

(2011) James F. Zawada et al.   BIOTECHNOLOGY AND BIOENGINEERING

Evaluation of a Group A Streptococcus synthetic oligosaccharide as vaccine candidate

(2010) Anna Kabanova et al.   VACCINE

Glycoconjugate vaccines and immune interference: A review

(2010) Ron Dagan et al.   VACCINE

Activation of the Nlrp3 Inflammasome by Streptococcus pyogenes Requires Streptolysin O and NF- B Activation but Proceeds Independently of TLR Signaling and P2X7 Receptor

(2009) J. Harder et al.   JOURNAL OF IMMUNOLOGY

Streptolysin O Promotes Group AStreptococcusImmune Evasion by Accelerated Macrophage Apoptosis

(2008) Anjuli M. Timmer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY