Molecular Mechanisms behind Safranal’s Toxicity to HepG2 Cells from Dual Omics

The regulatory role of nitric oxide in morphine‐induced analgesia in the descending path of pain from the dorsal hippocampus to the dorsolateral periaqueductal gray

(2022) Mahboobeh Hashemi et al.   EUROPEAN JOURNAL OF PAIN

Cationic amino acid transporters and their modulation by nitric oxide in cardiac muscle cells

(2021) R. Daniel Peluffo   Biophysical Reviews

Tumor-associated macrophages in classical Hodgkin lymphoma: hormetic relationship to outcome

(2020) Laura Werner et al.   Scientific Reports

NRF2 activation by reversible KEAP1 binding induces the antioxidant response in primary neurons and astrocytes of a Huntington’s disease mouse model

(2020) Daniele Moretti et al.   FREE RADICAL BIOLOGY AND MEDICINE

Attenuation of Nrf2/Keap1/ARE in Alzheimer’s Disease by Plant Secondary Metabolites: A Mechanistic Review

(2020) Sajad Fakhri et al.   MOLECULES

Role of the KEAP1-NRF2 Axis in Renal Cell Carcinoma

(2020) Sara Clerici et al.   Cancers

Evaluation of Biological Response of Lettuce (Lactuca sativa L.) and Weeds to Safranal Allelochemical of Saffron (Crocus sativus) by Using Static Exposure Method

(2019) Hossein Mardani et al.   MOLECULES

Natural compound safranal driven inhibition and dis-aggregation of α-synuclein fibrils

(2019) Shreyada S. Save et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Dihydroartemisinin potentiates antitumor activity of 5-fluorouracil against a resistant colorectal cancer cell line

(2018) Zhihan Yao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DnaJ homolog subfamily A member1 (DnaJ1) is a newly discovered anti-apoptotic protein regulated by azadirachtin in Sf9 cells

(2018) Benshui Shu et al.   BMC GENOMICS

Data processing, multi-omic pathway mapping, and metabolite activity analysis using XCMS Online

(2018) Erica M Forsberg et al.   Nature Protocols

Safranal induces DNA double-strand breakage and ER-stress-mediated cell death in hepatocellular carcinoma cells

(2018) Ala’a Al-Hrout et al.   Scientific Reports

Safranal and its analogs inhibit Escherichia coli ATP synthase and cell growth

(2017) Mason Liu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

A comprehensive review on anticancer mechanisms of the main carotenoid of saffron, crocin

(2017) Reyhane Hoshyar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Systems biology guided by XCMS Online metabolomics

(2017) Tao Huan et al.   NATURE METHODS

Safranal Inhibits HeLa Cell Viability by Perturbing the Reassembly Potential of Microtubules

(2017) Sanith Cheriyamundath et al.   PHYTOTHERAPY RESEARCH

AHSA1 regulates proliferation, apoptosis, migration, and invasion of osteosarcoma

(2016) Jianli Shao et al.   BIOMEDICINE & PHARMACOTHERAPY

Epidemiology of Hepatocellular Carcinoma in the Asia-Pacific Region

(2016) Ran Xu Zhu et al.   Gut and Liver

Depletion of the polyamines spermidine and spermine by overexpression of spermidine/spermineN1-acetyltransferase 1 (SAT1) leads to mitochondria-mediated apoptosis in mammalian cells

(2015) Swati Mandal et al.   BIOCHEMICAL JOURNAL

Treatment of Liver Cancer

(2015) Chun-Yu Liu et al.   Cold Spring Harbor Perspectives in Medicine

Interactive XCMS Online: Simplifying Advanced Metabolomic Data Processing and Subsequent Statistical Analyses

(2014) Harsha Gowda et al.   ANALYTICAL CHEMISTRY

Structure and Function of Human DnaJ Homologue Subfamily A Member 1 (DNAJA1) and Its Relationship to Pancreatic Cancer

(2014) Jaime L. Stark et al.   BIOCHEMISTRY

Anti-tumor activity of safranal against neuroblastoma cells

(2014) JabbariAzad Farahzad et al.   Pharmacognosy Magazine

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

Safranal ameliorates antioxidant enzymes and suppresses lipid peroxidation and nitric oxide formation in aged male rat liver

(2012) Seyed Kazem Farahmand et al.   BIOGERONTOLOGY

The anticancer effect of saffron in two p53 isogenic colorectal cancer cell lines

(2012) Khuloud Bajbouj et al.   BMC Complementary and Alternative Medicine

Metabolite discovery of helicidum in rat urine with XCMS based on the data of ultra performance liquid chromatography coupled to time-of-flight mass spectrometry

(2012) Qingfei Liu et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Defects in purine nucleotide metabolism lead to substantial incorporation of xanthine and hypoxanthine into DNA and RNA

(2012) B. Pang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biliverdin reductase A in the prevention of cellular senescence against oxidative stress

(2011) Sung Young Kim et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Saffron: A potential candidate for a novel anticancer drug against hepatocellular carcinoma

(2011) Amr Amin et al.   HEPATOLOGY

Mitochondrial reprogramming through cardiac oxygen sensors in ischaemic heart disease

(2010) Susana Cadenas et al.   CARDIOVASCULAR RESEARCH

Regulation of Mitochondrial Glutathione Redox Status and Protein Glutathionylation by Respiratory Substrates

(2010) Jerome Garcia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comprehensive LC−MSELipidomic Analysis using a Shotgun Approach and Its Application to Biomarker Detection and Identification in Osteoarthritis Patients

(2010) Jose M. Castro-Perez et al.   JOURNAL OF PROTEOME RESEARCH

Use of in vitro assays to assess the potential antiproliferative and cytotoxic effects of saffron (Crocus sativus L.) in human lung cancer cell line

(2010) Saeed Samarghandian et al.   Pharmacognosy Magazine

Solution structure and function of YndB, an AHSA1 protein from Bacillus subtilis

(2010) Jaime L. Stark et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS