A Toolbox for the Generation of Chemical Probes for Baculovirus IAP Repeat Containing Proteins

Hallmarks of Cancer: New Dimensions

(2022) Douglas Hanahan   Cancer Discovery

Interactive Tree Of Life (iTOL) v5: an online tool for phylogenetic tree display and annotation

(2021) Ivica Letunic et al.   NUCLEIC ACIDS RESEARCH

Evolution of Our Understanding of XIAP Deficiency

(2021) Anne C. A. Mudde et al.   Frontiers in Pediatrics

Future Therapeutic Directions for Smac-Mimetics

(2020) Emma Morrish et al.   Cells

Survivin at a glance

(2019) Sally P. Wheatley et al.   JOURNAL OF CELL SCIENCE

Negative regulation of autophagy by UBA6-BIRC6–mediated ubiquitination of LC3

(2019) Rui Jia et al.   eLife

The anti-apoptotic ubiquitin conjugating enzyme BIRC6/BRUCE regulates autophagosome-lysosome fusion

(2018) Fumiyo Ikeda   Autophagy

Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling

(2018) Matous Hrdinka et al.   EMBO JOURNAL

Synthesis and biological evaluation of indole-based UC-112 analogs as potent and selective survivin inhibitors

(2018) Qinghui Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms

(2018) Sudhir Kumar et al.   MOLECULAR BIOLOGY AND EVOLUTION

Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling

(2018) Tatiana Goncharov et al.   MOLECULAR CELL

In VivoKnockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs)

(2017) Nobumichi Ohoka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The NAIP/NLRC4 inflammasomes

(2015) Russell E Vance   CURRENT OPINION IN IMMUNOLOGY

Discovery of a Novel Class of Dimeric Smac Mimetics as Potent IAP Antagonists Resulting in a Clinical Candidate for the Treatment of Cancer (AZD5582)

(2013) Edward J. Hennessy et al.   JOURNAL OF MEDICINAL CHEMISTRY

Regulation of Apoptosis by Inhibitors of Apoptosis (IAPs)

(2013) Jean Berthelet et al.   Cells

Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism

(2012) Jennifer L. Allensworth et al.   BREAST CANCER RESEARCH AND TREATMENT

Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)

(2012) John A. Flygare et al.   JOURNAL OF MEDICINAL CHEMISTRY

IAPS : More than just inhibitors of apoptosis proteins

(2011) Laurence Dubrez-Daloz et al.   CELL CYCLE

Antagonists Induce a Conformational Change in cIAP1 That Promotes Autoubiquitination

(2011) E. C. Dueber et al.   SCIENCE

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

TRAF2-binding BIR1 domain of c-IAP2/MALT1 fusion protein is essential for activation of NF-κB

(2009) J B Garrison et al.   ONCOGENE

SM-164: A Novel, Bivalent Smac Mimetic That Induces Apoptosis and Tumor Regression by Concurrent Removal of the Blockade of cIAP-1/2 and XIAP

(2008) J. Lu et al.   CANCER RESEARCH

The evolution of BIR domain and its containing proteins

(2008) Lihuan Cao et al.   FEBS LETTERS