Isoform-selective inhibitory profile of 2-imidazoline-substituted benzene sulfonamides against a panel of human carbonic anhydrases

Dual Cyclooxygenase and Carbonic Anhydrase Inhibition by Nonsteroidal Anti-Inflammatory Drugs for the Treatment of Cancer

(2015) Celeste Monte et al.   CURRENT MEDICINAL CHEMISTRY

Probing the ‘bipolar’ nature of the carbonic anhydrase active site: Aromatic sulfonamides containing 1,3-oxazol-5-yl moiety as picomolar inhibitors of cytosolic CA I and CA II isoforms

(2015) Mikhail Krasavin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A Key Opinion Leader interview: insight into the research and career of Prof. Claudiu T Supuran

(2015) Claudia Palmer et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

How many carbonic anhydrase inhibition mechanisms exist?

(2015) Claudiu T. Supuran   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Carbonic Anhydrase Inhibitors with Dual-Tail Moieties To Match the Hydrophobic and Hydrophilic Halves of the Carbonic Anhydrase Active Site

(2015) Rajendra P. Tanpure et al.   JOURNAL OF MEDICINAL CHEMISTRY

Facile Pd-catalyzed amination of imidazolin-1-yl chloroazines under microwave irradiation: toward a new kinase-inhibitory chemotype

(2015) Prashant Mujumdar et al.   TETRAHEDRON LETTERS

Recent Developments in Targeting Carbonic Anhydrase IX for Cancer Therapeutics

(2015) Paul C. McDonald et al.   Oncotarget

Potent, orally available, selective COX-2 inhibitors based on 2-imidazoline core

(2014) Pakornwit Sarnpitak et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Pd-Catalyzed N-arylation of 2-imidazolines Provides Convenient Access to Selective Cyclooxygenase-2 Inhibitors

(2013) Mikhail Krasavin   LETTERS IN ORGANIC CHEMISTRY

Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?

(2012) Vincenzo Alterio et al.   CHEMICAL REVIEWS

Secondary/tertiary benzenesulfonamides with inhibitory action against the cytosolic human carbonic anhydrase isoforms I and II

(2012) Cemalettin Alp et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Structure-based drug discovery of carbonic anhydrase inhibitors

(2012) Claudiu T. Supuran   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Novel diversely substituted 1-heteroaryl-2-imidazolines for fragment-based drug discovery

(2012) Mikhail Krasavin   TETRAHEDRON LETTERS

Carbonic anhydrase inhibitors: inhibition of human and bovine isoenzymes by benzenesulphonamides, cyclitols and phenolic compounds

(2011) Deniz Ekinci et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Carbonic anhydrase inhibitors:in vitroinhibition of α isoforms (hCA I, hCA II, bCA III, hCA IV) by flavonoids

(2011) Derya Ekinci et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Dithiocarbamates strongly inhibit the β-class carbonic anhydrases fromMycobacterium tuberculosis

(2011) Alfonso Maresca et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Interfering with pH regulation in tumours as a therapeutic strategy

(2011) Dario Neri et al.   NATURE REVIEWS DRUG DISCOVERY

Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency

(2010) Fabio Pacchiano et al.   CHEMICAL COMMUNICATIONS

Design of Zinc Binding Functions for Carbonic Anhydrase Inhibitors

(2008) Jean-Louis Montero et al.   CURRENT PHARMACEUTICAL DESIGN

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

(2008) Claudiu T. Supuran   NATURE REVIEWS DRUG DISCOVERY