Nanospermidine in Combination with Nanofenretinide Induces Cell Death in Neuroblastoma Cell Lines

YAP/TAZ drives cell proliferation and tumour growth via a polyamine–eIF5A hypusination–LSD1 axis

(2022) Hongde Li et al.   NATURE CELL BIOLOGY

Polyamine import and accumulation causes immunomodulation in macrophages engulfing apoptotic cells

(2022) Alexandra L. McCubbrey et al.   Cell Reports

RARE-08. POTENTIAL NEW THERAPIES FOR DIFFUSE INTRINSIC PONTINE GLIOMAS IDENTIFIED THROUGH HIGH THROUGHPUT DRUG SCREENING

(2021) Dannielle Upton et al.   NEURO-ONCOLOGY

The role of polyamines in gastric cancer

(2021) Kara M. McNamara et al.   ONCOGENE

Protective Role of Spermidine in Colitis and Colon Carcinogenesis

(2021) Alain P. Gobert et al.   GASTROENTEROLOGY

The mitochondrial PKCδ/retinol signal complex exerts real-time control on energy homeostasis

(2020) Youn-Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

ROS in cancer therapy: the bright side of the moon

(2020) Bruno Perillo et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Spermidine as a target for cancer therapy

(2020) Jingjing Fan et al.   PHARMACOLOGICAL RESEARCH

Cell Motility and Cancer

(2020) Ildefonso M. De la Fuente et al.   Cancers

Nanomicellar Lenalidomide–Fenretinide Combination Suppresses Tumor Growth in an MYCN Amplified Neuroblastoma Tumor

(2020) Isabella Orienti et al.   International Journal of Nanomedicine

DIPG-07. HIGH THROUGHPUT DRUG SCREENING IDENTIFIES POTENTIAL NEW THERAPIES FOR DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPGs)

(2020) Dannielle Upton et al.   NEURO-ONCOLOGY

The role of polyamines in the regulation of macrophage polarization and function

(2019) Yvonne L. Latour et al.   AMINO ACIDS

Image deconvolution for confocal laser scanning microscopy using constrained total variation with a gradient field

(2019) Tao He et al.   APPLIED OPTICS

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation

(2019) Daniel J. Puleston et al.   Cell Metabolism

Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence

(2019) Hanlin Zhang et al.   MOLECULAR CELL

A Novel Nanomicellar Combination of Fenretinide and Lenalidomide Shows Marked Antitumor Activity in a Neuroblastoma Xenograft Model

(2019) Isabella Orienti et al.   Drug Design Development and Therapy

The old and new biochemistry of polyamines

(2018) Dong-Hun Bae et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Spermidine‑induced growth inhibition and apoptosis via autophagic activation in cervical cancer

(2018) Yu Chen et al.   ONCOLOGY REPORTS

Oil for the cancer engine: The cross-talk between oncogenic signaling and polyamine metabolism

(2018) Amaia Arruabarrena-Aristorena et al.   Science Advances

Polyamine catabolism and oxidative damage

(2018) Tracy Murray Stewart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Polyamine Catabolism by N1,N11-Diethylnorspermine in Hepatic HepaRG Cells Induces Dedifferentiation and Mesenchymal-Like Phenotype

(2018) Olga N. Ivanova et al.   Cells

Characterising live cell behaviour: Traditional label-free and quantitative phase imaging approaches

(2017) Richard Kasprowicz et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Reactive Oxygen Species–Mediated Synergism of Fenretinide and Romidepsin in Preclinical Models of T-cell Lymphoid Malignancies

(2017) Monish R. Makena et al.   MOLECULAR CANCER THERAPEUTICS

Label-free imaging to study phenotypic behavioural traits of cells in complex co-cultures

(2016) Rakesh Suman et al.   Scientific Reports

Current Approaches for Improving Intratumoral Accumulation and Distribution of Nanomedicines

(2015) Mikhail O Durymanov et al.   Theranostics

Digital Holographic Microscopy: A Quantitative Label-Free Microscopy Technique for Phenotypic Screening

(2014) Benjamin Rappaz et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Live-cell mass profiling: an emerging approach in quantitative biophysics

(2014) Thomas A Zangle et al.   NATURE METHODS

Autophagy is a critical regulator of memory CD8+ T cell formation

(2014) Daniel J Puleston et al.   eLife

Challenges and Key Considerations of the Enhanced Permeability and Retention Effect for Nanomedicine Drug Delivery in Oncology

(2013) U. Prabhakar et al.   CANCER RESEARCH

Ptychography – a label free, high-contrast imaging technique for live cells using quantitative phase information

(2013) Joanne Marrison et al.   Scientific Reports

The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo

(2012) Hiroshi Maeda et al.   ADVANCED DRUG DELIVERY REVIEWS

A Water Soluble CoQ10 Formulation Improves Intracellular Distribution and Promotes Mitochondrial Respiration in Cultured Cells

(2012) Christian Bergamini et al.   PLoS One

Generalized cell morphological parameters based on interferometric phase microscopy and their application to cell life cycle characterization

(2012) Pinhas Girshovitz et al.   Biomedical Optics Express

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

(2010) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS

Delivering nanomedicine to solid tumors

(2010) Rakesh K. Jain et al.   Nature Reviews Clinical Oncology

Optical ptychography: a practical implementation with useful resolution

(2010) Andrew M. Maiden et al.   OPTICS LETTERS

Why are tumour blood vessels abnormal and why is it important to know?

(2009) J A Nagy et al.   BRITISH JOURNAL OF CANCER

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY