Coordinated regulation of BACH1 and mitochondrial metabolism through tumor-targeted self-assembled nanoparticles for effective triple negative breast cancer combination therapy

Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer

(2021) Archis Bagati et al.   CANCER CELL

Berberine regulates the Notch1/PTEN/PI3K/AKT/mTOR pathway and acts synergistically with 17-AAG and SAHA in SW480 colon cancer cells

(2021) Ge Li et al.   PHARMACEUTICAL BIOLOGY

A Novel Therapeutic Target, BACH1, Regulates Cancer Metabolism

(2021) Joselyn Padilla et al.   Cells

The transcription factor BACH1 at the crossroads of cancer biology: From epithelial–mesenchymal transition to ferroptosis

(2021) Kazuhiko Igarashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Metabolism Targeted Nanoplatform for Efficient Triple‐Negative Breast Cancer Combination Therapy

(2021) Lu Lu et al.   Advanced Healthcare Materials

Targeting Chondroitin Sulfate Reduces Invasiveness of Glioma Cells by Suppressing CD44 and Integrin β1 Expression

(2021) Yin-Hung Chu et al.   Cells

BACH1 promotes pancreatic cancer metastasis by repressing epithelial genes and enhancing epithelial-mesenchymal transition

(2020) Masaki Sato et al.   CANCER RESEARCH

Nanoparticles in combating cancer: Opportunities and limitations. A brief review.

(2020) Elzbieta Pedziwiatr-Werbicka et al.   CURRENT MEDICINAL CHEMISTRY

lncRNA RMRP Prevents Mitochondrial Dysfunction and Cardiomyocyte Apoptosis via the miR-1-5p/hsp70 Axis in LPS-Induced Sepsis Mice

(2020) Ying Han et al.   INFLAMMATION

Berberine Impairs the Survival of Triple Negative Breast Cancer Cells: Cellular and Molecular Analyses

(2020) Lamyae El Khalki et al.   MOLECULES

Co-delivery of silybin and paclitaxel by dextran-based nanoparticles for effective anti-tumor treatment through chemotherapy sensitization and microenvironment modulation

(2020) Meirong Huo et al.   JOURNAL OF CONTROLLED RELEASE

Defective NADPH production in mitochondrial disease complex I causes inflammation and cell death

(2020) Eduardo Balsa et al.   Nature Communications

Targeted Heating of Mitochondria Greatly Augments Nanoparticle‐Mediated Cancer Chemotherapy

(2020) Jiangsheng Xu et al.   Advanced Healthcare Materials

Berberine diminishes cancer cell PD-L1 expression and facilitates antitumor immunity via inhibiting the deubiquitination activity of CSN5

(2020) Yang Liu et al.   Acta Pharmaceutica Sinica B

Pembrolizumab and atezolizumab in triple-negative breast cancer

(2020) Dorota Kwapisz   CANCER IMMUNOLOGY IMMUNOTHERAPY

Chondroitin sulfate conjugation facilitates tumor cell internalization of albumin nanoparticles for brain-targeted delivery of temozolomide via CD44 receptor-mediated targeting

(2020) Ritu R. Kudarha et al.   Drug Delivery and Translational Research

Triple negative breast cancer in the era of miRNA

(2020) Hussein Sabit et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Effect of Capecitabine Maintenance Therapy Using Lower Dosage and Higher Frequency vs Observation on Disease-Free Survival Among Patients With Early-Stage Triple-Negative Breast Cancer Who Had Received Standard Treatment

(2020) Xi Wang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

PGRN−/− TAMs-derived exosomes inhibit breast cancer cell invasion and migration and its mechanism exploration

(2020) Shujun Yue et al.   LIFE SCIENCES

Endogenous retroelement activation by epigenetic therapy reverses the Warburg effect and elicits mitochondrial-mediated cancer cell death

(2020) Vicente Fresquet et al.   Cancer Discovery

Olaparib monotherapy as primary treatment in unselected triple negative breast cancer

(2020) H.P. Eikesdal et al.   ANNALS OF ONCOLOGY

Cancer cell metabolism: Rewiring the mitochondrial hub

(2020) Gabriela L. Oliveira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Chondroitin sulfate-hybridized zein nanoparticles for tumor-targeted delivery of docetaxel

(2020) Han Sol Lee et al.   CARBOHYDRATE POLYMERS

Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism

(2019) Jiyoung Lee et al.   NATURE

Restraining Cancer Cells by Dual Metabolic Inhibition with a Mitochondrion-Targeted Platinum(II) Complex

(2019) Kun Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1

(2019) Luca Lignitto et al.   CELL

BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis

(2019) Clotilde Wiel et al.   CELL

Different mechanisms involved in the berberine‐induced antiproliferation effects in triple‐negative breast cancer cell lines

(2019) Yen‐Shu Lin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Hyaluronidase, TMEM2, Promotes ER Homeostasis and Longevity Independent of the UPRER

(2019) Robert Thomas Schinzel et al.   CELL

A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds

(2018) Balaraman Kalyanaraman et al.   Redox Biology

Hypoxia-induced up-regulation of VASP promotes invasiveness and metastasis of hepatocellular carcinoma

(2018) Zhikui Liu et al.   Theranostics

Plasma heme-induced renal toxicity is related to a capillary rarefaction

(2017) Nahid Tabibzadeh et al.   Scientific Reports

Cancer metabolism: a therapeutic perspective

(2016) Ubaldo E. Martinez-Outschoorn et al.   Nature Reviews Clinical Oncology

Discovery of mitochondria-targeting berberine derivatives as the inhibitors of proliferation, invasion and migration against rat C6 and human U87 glioma cells

(2015) Shengnan Fu et al.   MedChemComm