Exercise-derived peptide protects against pathological cardiac remodeling

DYRK1B-STAT3 Drives Cardiac Hypertrophy and Heart Failure by Impairing Mitochondrial Bioenergetics

(2022) Lingfang Zhuang et al.   CIRCULATION

Consensus Transcriptional Landscape of Human End‐Stage Heart Failure

(2021) Ricardo O. Ramirez Flores et al.   Journal of the American Heart Association

Identification of candidate biomarkers and therapeutic agents for heart failure by bioinformatics analysis

(2021) Vijayakrishna Kolur et al.   BMC Cardiovascular Disorders

Regulation of STAT3 and its role in cardioprotection by conditioning: focus on non-genomic roles targeting mitochondrial function

(2021) Stefano Comità et al.   BASIC RESEARCH IN CARDIOLOGY

Mechanisms Involved in Cardioprotection Induced by Physical Exercise

(2020) Claudia Penna et al.   ANTIOXIDANTS & REDOX SIGNALING

Intermittent hypoxia mediated by TSP1 dependent on STAT3 induces cardiac fibroblast activation and cardiac fibrosis

(2020) Qiankun Bao et al.   eLife

Molecular Choreography of Acute Exercise

(2020) Kévin Contrepois et al.   CELL

VSMC-Specific Deletion of FAM3A Attenuated AngII-Promoted Hypertension and Cardiovascular Hypertrophy

(2020) Rui Xiang et al.   CIRCULATION RESEARCH

Celastrol Attenuates Angiotensin II–Induced Cardiac Remodeling by Targeting STAT3

(2020) Shiju Ye et al.   CIRCULATION RESEARCH

Extracellular vesicles and cardiovascular system: Biomarkers and Cardioprotective Effectors

(2020) Saveria Femminò et al.   VASCULAR PHARMACOLOGY

Longterm Exercise-Derived Exosomal miR-342-5p: A Novel Exerkine for Cardioprotection

(2019) Zuoxu Hou et al.   CIRCULATION RESEARCH

Sedentary Behavior, Exercise, and Cardiovascular Health

(2019) Carl J. Lavie et al.   CIRCULATION RESEARCH

Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association

(2019) Emelia J. Benjamin et al.   CIRCULATION

Endothelial Cells Regulate Physiological Cardiomyocyte Growth via VEGFR2 -Mediated Paracrine Signaling

(2019) Riikka Kivelä et al.   CIRCULATION

miR-431-5p Knockdown Protects Against Angiotensin II–Induced Hypertension and Vascular Injury

(2019) Ku-Geng Huo et al.   HYPERTENSION

Molecular Mechanisms of Cardiac Remodeling and Regeneration in Physical Exercise

(2019) Dominik Schüttler et al.   Cells

Metabolic Coordination of Physiological and Pathological Cardiac Remodeling

(2018) Andrew A. Gibb et al.   CIRCULATION RESEARCH

Multiplex quantification identifies novel exercise-regulated myokines/cytokines in plasma and in glycolytic and oxidative skeletal muscle

(2018) Hannah Little et al.   MOLECULAR & CELLULAR PROTEOMICS

Mechanisms of physiological and pathological cardiac hypertrophy

(2018) Michinari Nakamura et al.   Nature Reviews Cardiology

Aerobic exercise and cardiopulmonary fitness in childhood cancer survivors treated with a cardiotoxic agent: a meta-analysis

(2018) Alexander Bourdon et al.   SUPPORTIVE CARE IN CANCER

Coiled-coil domain-containing 80 accelerates atherosclerosis development through decreasing lipoprotein lipase expression via ERK1/2 phosphorylation and TET2 expression

(2018) Duo Gong et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Heart failure

(2017) Marco Metra et al.   LANCET

Multiplexed Temporal Quantification of the Exercise-regulated Plasma Peptidome

(2017) Benjamin L. Parker et al.   MOLECULAR & CELLULAR PROTEOMICS

Adipose Tissue and Serum CCDC80 in Obesity and Its Association with Related Metabolic Disease

(2017) Óscar Osorio-Conles et al.   MOLECULAR MEDICINE

miR-17-3p Contributes to Exercise-Induced Cardiac Growth and Protects against Myocardial Ischemia-Reperfusion Injury

(2017) Jing Shi et al.   Theranostics

Global mRNA sequencing of human skeletal muscle: Search for novel exercise-regulated myokines

(2017) S. Pourteymour et al.   Molecular Metabolism

The Effects of Acute and Chronic Exercise on Skeletal Muscle Proteome

(2016) Bernardo A. Petriz et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Epidemiology and aetiology of heart failure

(2016) Boback Ziaeian et al.   Nature Reviews Cardiology

The potential of endurance exercise-derived exosomes to treat metabolic diseases

(2016) Adeel Safdar et al.   Nature Reviews Endocrinology

Gp130-mediated STAT3 activation by S-propargyl-cysteine, an endogenous hydrogen sulfide initiator, prevents doxorubicin-induced cardiotoxicity

(2016) J Wu et al.   Cell Death & Disease

Comparative Transcriptome Analysis Identifies CCDC80 as a Novel Gene Associated with Pulmonary Arterial Hypertension

(2016) Shota Sasagawa et al.   Frontiers in Pharmacology

Exercise Controls Non-Coding RNAs

(2015) Shizuka Uchida et al.   Cell Metabolism

miR-222 Is Necessary for Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling

(2015) Xiaojun Liu et al.   Cell Metabolism

Revisiting Cardiac Cellular CompositionNovelty and Significance

(2015) Alexander R. Pinto et al.   CIRCULATION RESEARCH

Peptide therapeutics: current status and future directions

(2015) Keld Fosgerau et al.   DRUG DISCOVERY TODAY

Cardiosome mediated regulation of MMP9 in diabetic heart: role of mir29b and mir455 in exercise

(2015) Pankaj Chaturvedi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Meteorin-like Is a Hormone that Regulates Immune-Adipose Interactions to Increase Beige Fat Thermogenesis

(2014) Rajesh R. Rao et al.   CELL

Angiotensin II and Vascular Injury

(2014) Augusto C. Montezano et al.   CURRENT HYPERTENSION REPORTS

Proteomic Analysis of C2C12 Myoblast and Myotube Exosome-Like Vesicles: A New Paradigm for Myoblast-Myotube Cross Talk?

(2014) Alexis Forterre et al.   PLoS One

Exercise Metabolism and the Molecular Regulation of Skeletal Muscle Adaptation

(2013) Brendan Egan et al.   Cell Metabolism

Metastasis-associated protein, S100A4 mediates cardiac fibrosis potentially through the modulation of p53 in cardiac fibroblasts

(2013) Yodo Tamaki et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Identification of Steroid-Sensitive Gene-1/Ccdc80 as a JAK2-Binding Protein

(2013) Erin E. O'Leary et al.   MOLECULAR ENDOCRINOLOGY

Muscles, exercise and obesity: skeletal muscle as a secretory organ

(2012) Bente K. Pedersen et al.   Nature Reviews Endocrinology

Exercise-Induced Cardiac Remodeling

(2012) Rory B. Weiner et al.   PROGRESS IN CARDIOVASCULAR DISEASES

The Progression of Hypertensive Heart Disease

(2011) Mark H. Drazner   CIRCULATION

Mitochondrial STAT3 Activation and Cardioprotection by Ischemic Postconditioning in Pigs With Regional Myocardial Ischemia/Reperfusion

(2011) Gerd Heusch et al.   CIRCULATION RESEARCH

Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study

(2011) Chi Pang Wen et al.   LANCET

The microRNA miR-696 regulates PGC-1α in mouse skeletal muscle in response to physical activity

(2010) Wataru Aoi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

STAT3 and cardiac remodeling

(2010) Arash Haghikia et al.   HEART FAILURE REVIEWS

Bidirectional Modulation of Adipogenesis by the Secreted Protein Ccdc80/DRO1/URB

(2009) Frédéric Tremblay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

URB is abundantly expressed in adipose tissue and dysregulated in obesity

(2008) Takuya Okada et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Rapid exercise-induced changes in PGC-1α mRNA and protein in human skeletal muscle

(2008) Anila S. Mathai et al.   JOURNAL OF APPLIED PHYSIOLOGY