VSMC-Specific Deletion of FAM3A Attenuated AngII-Promoted Hypertension and Cardiovascular Hypertrophy

Status of Hypertension in China

(2018) Zengwu Wang et al.   CIRCULATION

Research Techniques Made Simple: Sample Size Estimation and Power Calculation

(2018) Sigrun A.J. Schmidt et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

HSF1 deficiency accelerates the transition from pressure overload-induced cardiac hypertrophy to heart failure through endothelial miR-195a-3p-mediated impairment of cardiac angiogenesis

(2018) Shijun Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

FAM3 gene family: A promising therapeutical target for NAFLD and type 2 diabetes

(2018) Xiaoyan Zhang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Homocysteine directly interacts and activates the angiotensin II type I receptor to aggravate vascular injury

(2018) Tuoyi Li et al.   Nature Communications

HSF1 phosphorylation by ERK/GSK3 suppresses RNF126 to sustain IGF-IIR expression for hypertension-induced cardiomyocyte hypertrophy

(2017) Chih-Yang Huang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Homocysteine and all-cause mortality in hypertensive adults without pre-existing cardiovascular conditions

(2017) Benjamin Xu et al.   MEDICINE

Regulation of heat shock transcription factors and their roles in physiology and disease

(2017) Rocio Gomez-Pastor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Associations of plasma homocysteine levels with peripheral systolic blood pressure and noninvasive central systolic blood pressure in a community-based Chinese population

(2017) Mohetaboer Momin et al.   Scientific Reports

Pioglitazone, a PPARγ agonist, attenuates PDGF-induced vascular smooth muscle cell proliferation through AMPK-dependent and AMPK-independent inhibition of mTOR/p70S6K and ERK signaling

(2016) Islam Osman et al.   BIOCHEMICAL PHARMACOLOGY

Heat shock factor-1 knockout enhances cholesterol 7α-hydroxylase (CYP7A1) and multidrug transporter (MDR1) gene expressions to attenuate atherosclerosis

(2016) Karthikeyan Krishnamurthy et al.   CARDIOVASCULAR RESEARCH

Genetic and Pharmacologic Inhibition of the Chemokine Receptor CXCR2 Prevents Experimental Hypertension and Vascular DysfunctionClinical Perspective

(2016) Lei Wang et al.   CIRCULATION

FAM3A attenuates ER stress-induced mitochondrial dysfunction and apoptosis via CHOP-Wnt pathway

(2016) Qing Song et al.   NEUROCHEMISTRY INTERNATIONAL

Angiotensin II and Vascular Injury

(2014) Augusto C. Montezano et al.   CURRENT HYPERTENSION REPORTS

Updated National and International Hypertension Guidelines: A Review of Current Recommendations

(2014) Sverre Kjeldsen et al.   DRUGS

FAM3A promotes vascular smooth muscle cell proliferation and migration and exacerbates neointima formation in rat artery after balloon injury

(2014) Shi Jia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Bnip3 mediates doxorubicin-induced cardiac myocyte necrosis and mortality through changes in mitochondrial signaling

(2014) Rimpy Dhingra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FAM3A is a target gene of peroxisome proliferator-activated receptor gamma

(2013) Yanlan Zhou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Hepatic Overexpression of ATP Synthase   Subunit Activates PI3K/Akt Pathway to Ameliorate Hyperglycemia of Diabetic Mice

(2013) C. Wang et al.   DIABETES

FAM3A activates PI3K p110α/Akt signaling to ameliorate hepatic gluconeogenesis and lipogenesis

(2013) Chunjiong Wang et al.   HEPATOLOGY

Intracellular and extracellular adenosine triphosphate in regulation of insulin secretion from pancreaticβcells (细胞内外三磷酸腺苷对胰岛β细胞胰岛素分泌的调控作用)

(2013) Chunjiong Wang et al.   Journal of Diabetes

Protective role of vascular smooth muscle cell PPARγ in angiotensin II-induced vascular disease

(2012) Chiara Marchesi et al.   CARDIOVASCULAR RESEARCH

HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers

(2012) Marc L. Mendillo et al.   CELL

Regulation of angiotensin II receptors beyond the classical pathway

(2012) Masatsugu Horiuchi et al.   CLINICAL SCIENCE

Blood pressure and water regulation: understanding sex hormone effects within and between men and women

(2012) Megan M. Wenner et al.   JOURNAL OF PHYSIOLOGY-LONDON

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Stephen S Lim et al.   LANCET

Targeted Disruption of the Prostaglandin E 2 E-Prostanoid 2 Receptor Exacerbates Vascular Neointimal Formation in Mice

(2011) Sen Zhu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Effects of PPARγ on hypertension, atherosclerosis, and chronic kidney disease

(2010) Akira Sugawara et al.   ENDOCRINE JOURNAL

Vascular Smooth Muscle Cell–Selective Peroxisome Proliferator–Activated Receptor-γ Deletion Leads to Hypotension

(2009) Lin Chang et al.   CIRCULATION

Role of NMDA receptor in homocysteine-induced activation of Mitogen-Activated Protein Kinase and Phosphatidyl Inositol 3-Kinase pathways in cultured human vascular smooth muscle cells

(2009) Gabriella Doronzo et al.   THROMBOSIS RESEARCH

Central Role of Gqin the Hypertrophic Signal Transduction of Angiotensin II in Vascular Smooth Muscle Cells

(2008) Haruhiko Ohtsu et al.   ENDOCRINOLOGY

Extracellular ATP and zinc are co-secreted with insulin and activate multiple P2X purinergic receptor channels expressed by islet beta-cells to potentiate insulin secretion

(2008) Clintoria Richards-Williams et al.   Purinergic Signalling

Adenoviral gene transfer of viral interleukin-10 protects cerebrovascular impairment induced by lysophosphatidylcholine

(2007) Hui Kang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY